STRINGSTRING
SMAD7 SMAD7 ENSRBIP00000027645 ENSRBIP00000027645 NEDD4L NEDD4L IRX5 IRX5 MAPK1 MAPK1 CCNT2 CCNT2 SMAD4 SMAD4 CCNC CCNC ENSRBIP00000018271 ENSRBIP00000018271 IRX6 IRX6 LOC108524569 LOC108524569 PPM1A PPM1A PCSK4 PCSK4 YBX1 YBX1 LOC108545049 LOC108545049 WWTR1 WWTR1 FURIN FURIN RBL1 RBL1 SKI SKI HDAC1 HDAC1 LOC108527145 LOC108527145 UBE2D1 UBE2D1 IRX2 IRX2 MEN1 MEN1 LOC108525288 LOC108525288 TFDP1 TFDP1 MEIS1 MEIS1 ENSRBIP00000012514 ENSRBIP00000012514 SMAD2 SMAD2 LOC108529358 LOC108529358 ENSRBIP00000008820 ENSRBIP00000008820 UBA52 UBA52 TFDP2 TFDP2 MEIS3 MEIS3 SMAD3 SMAD3 IRX4 IRX4 TFDP3 TFDP3 LOC108529634 LOC108529634 TGIF1 TGIF1 MKX MKX IRX3 IRX3 LOC108540530 LOC108540530 ENSRBIP00000004747 ENSRBIP00000004747 ENSRBIP00000004187 ENSRBIP00000004187 ENSRBIP00000003802 ENSRBIP00000003802 CCNK CCNK E2F5 E2F5 COL1A2 COL1A2 ENSRBIP00000001317 ENSRBIP00000001317 SMURF2 SMURF2 IRX1 IRX1 ENSRBIP00000000704 ENSRBIP00000000704 RPS27A RPS27A MAPK3 MAPK3 SERPINE1 SERPINE1 ENSRBIP00000021679 ENSRBIP00000021679 CCNQ CCNQ ENSRBIP00000020228 ENSRBIP00000020228 CCNT1 CCNT1 PARP1 PARP1 RNF111 RNF111 TRIM33 TRIM33 TGIF2 TGIF2 LOC108519608 LOC108519608 ENSRBIP00000037879 ENSRBIP00000037879 STAT1 STAT1 SNW1 SNW1 NCOR1 NCOR1 SP1 SP1 CDK8 CDK8 E2F4 E2F4 EP300 EP300 MYC MYC SKIL SKIL CDK9 CDK9 ENSRBIP00000030441 ENSRBIP00000030441 NCOR2 NCOR2 ENSRBIP00000029173 ENSRBIP00000029173 ATP1B4 ATP1B4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD7Mothers against decapentaplegic homolog. (431 aa)
ENSRBIP00000027645Homeobox domain-containing protein. (270 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1227 aa)
IRX5Iroquois homeobox 5. (483 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (721 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CCNCCyclin C; Belongs to the cyclin family. (265 aa)
ENSRBIP00000018271Hist_deacetyl domain-containing protein. (180 aa)
IRX6Iroquois homeobox 6. (444 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (724 aa)
YBX1CSD_1 domain-containing protein. (282 aa)
LOC108545049CYCLIN domain-containing protein; Belongs to the cyclin family. (264 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (787 aa)
RBL1RB transcriptional corepressor like 1. (1069 aa)
SKISKI proto-oncogene. (637 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
LOC108527145Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
IRX2Iroquois homeobox 2. (446 aa)
MEN1Menin 1. (610 aa)
LOC108525288Homeobox domain-containing protein. (242 aa)
TFDP1Transcription factor. (410 aa)
MEIS1Meis homeobox 1. (398 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
LOC108529358CSD_1 domain-containing protein. (284 aa)
ENSRBIP00000008820Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (470 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
TFDP2Transcription factor. (429 aa)
MEIS3Meis homeobox 3. (460 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
IRX4Iroquois homeobox 4. (515 aa)
TFDP3Transcription factor. (408 aa)
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
TGIF1TGFB induced factor homeobox 1. (367 aa)
MKXMohawk homeobox. (352 aa)
IRX3Iroquois homeobox 3. (502 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
CCNKCyclin K; Belongs to the cyclin family. (542 aa)
E2F5E2F transcription factor 5. (345 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (719 aa)
IRX1Iroquois homeobox 1. (466 aa)
ENSRBIP00000000704Uncharacterized protein. (92 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (429 aa)
ENSRBIP00000021679Uncharacterized protein. (269 aa)
CCNQCyclin N-terminal domain-containing protein. (186 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (725 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
RNF111Ring finger protein 111. (994 aa)
TRIM33Tripartite motif containing 33. (1123 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
LOC108519608Uncharacterized protein. (246 aa)
ENSRBIP00000037879PPM-type phosphatase domain-containing protein. (342 aa)
STAT1Signal transducer and activator of transcription. (787 aa)
SNW1SKIP_SNW domain-containing protein. (536 aa)
NCOR1Nuclear receptor corepressor 1. (2441 aa)
SP1Sp1 transcription factor. (769 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (482 aa)
E2F4E2F transcription factor 4. (415 aa)
EP300E1A binding protein p300. (2296 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
SKILSKI like proto-oncogene. (692 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
ENSRBIP00000030441SKIP_SNW domain-containing protein. (530 aa)
NCOR2Nuclear receptor corepressor 2. (2488 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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