44 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSRBIP00000008820	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (470 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	ENSRBIP00000012514	Ubiquitin-like domain-containing protein. (121 aa)
	LOC108525288	Homeobox domain-containing protein. (242 aa)
	NEDD4L	NEDD4 like E3 ubiquitin protein ligase. (1227 aa)
	ENSRBIP00000027645	Homeobox domain-containing protein. (270 aa)
	SMAD7	Mothers against decapentaplegic homolog. (431 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
	ENSRBIP00000029173	Ubiquitin-like domain-containing protein. (166 aa)
	NCOR2	Nuclear receptor corepressor 2. (2488 aa)
	ENSRBIP00000030441	SKIP_SNW domain-containing protein. (530 aa)
	SKIL	SKI like proto-oncogene. (692 aa)
	NCOR1	Nuclear receptor corepressor 1. (2441 aa)
	SNW1	SKIP_SNW domain-containing protein. (536 aa)
	STAT1	Signal transducer and activator of transcription. (787 aa)
	ENSRBIP00000037879	PPM-type phosphatase domain-containing protein. (342 aa)
	LOC108519608	Uncharacterized protein. (246 aa)
	SMAD3	Mothers against decapentaplegic homolog. (480 aa)
	LOC108529634	Ubiquitin-like domain-containing protein. (128 aa)
	TGIF1	TGFB induced factor homeobox 1. (367 aa)
	UBE2D1	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC108527145	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
	WWTR1	WW domain containing transcription regulator 1. (400 aa)
	ENSRBIP00000018271	Hist_deacetyl domain-containing protein. (180 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	ENSRBIP00000020228	Uncharacterized protein. (132 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	SKI	SKI proto-oncogene. (637 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
	LOC108540530	Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	LOC108524569	Ubiquitin-like domain-containing protein. (141 aa)
	UBA52	Ubiquitin-like domain-containing protein. (232 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
	TGIF2	TGFB induced factor homeobox 2. (237 aa)
	TRIM33	Tripartite motif containing 33. (1123 aa)
	RNF111	Ring finger protein 111. (994 aa)
	ENSRBIP00000004747	Ubiquitin-like domain-containing protein. (128 aa)
	ENSRBIP00000004187	Ubiquitin-like domain-containing protein. (153 aa)
	ENSRBIP00000003802	Ubiquitin-like domain-containing protein. (84 aa)
	ENSRBIP00000001317	Ubiquitin-like domain-containing protein. (155 aa)
	SMURF2	SMAD specific E3 ubiquitin protein ligase 2. (719 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1B4	ENSRBIP00000030441	ENSRBIP00000028500	ENSRBIP00000030441	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SKIP_SNW domain-containing protein.	0.681
ATP1B4	MAPK1	ENSRBIP00000028500	ENSRBIP00000026426	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.900
ATP1B4	MAPK3	ENSRBIP00000028500	ENSRBIP00000000532	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.900
ATP1B4	SNW1	ENSRBIP00000028500	ENSRBIP00000036300	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SKIP_SNW domain-containing protein.	0.681
ENSRBIP00000001317	ENSRBIP00000004747	ENSRBIP00000001317	ENSRBIP00000004747	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.803
ENSRBIP00000001317	ENSRBIP00000012514	ENSRBIP00000001317	ENSRBIP00000012514	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.806
ENSRBIP00000001317	ENSRBIP00000020228	ENSRBIP00000001317	ENSRBIP00000020228	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.812
ENSRBIP00000001317	LOC108519608	ENSRBIP00000001317	ENSRBIP00000041012	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.441
ENSRBIP00000001317	LOC108524569	ENSRBIP00000001317	ENSRBIP00000025262	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.810
ENSRBIP00000001317	LOC108529634	ENSRBIP00000001317	ENSRBIP00000005412	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.803
ENSRBIP00000001317	LOC108540530	ENSRBIP00000001317	ENSRBIP00000005159	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.978
ENSRBIP00000001317	NEDD4L	ENSRBIP00000001317	ENSRBIP00000027479	Ubiquitin-like domain-containing protein.	NEDD4 like E3 ubiquitin protein ligase.	0.653
ENSRBIP00000001317	PARP1	ENSRBIP00000001317	ENSRBIP00000043459	Ubiquitin-like domain-containing protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.400
ENSRBIP00000001317	RNF111	ENSRBIP00000001317	ENSRBIP00000042449	Ubiquitin-like domain-containing protein.	Ring finger protein 111.	0.535
ENSRBIP00000001317	RPS27A	ENSRBIP00000001317	ENSRBIP00000000621	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.900
ENSRBIP00000001317	SMURF2	ENSRBIP00000001317	ENSRBIP00000001230	Ubiquitin-like domain-containing protein.	SMAD specific E3 ubiquitin protein ligase 2.	0.761
ENSRBIP00000001317	UBA52	ENSRBIP00000001317	ENSRBIP00000008282	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.986
ENSRBIP00000001317	UBE2D1	ENSRBIP00000001317	ENSRBIP00000015790	Ubiquitin-like domain-containing protein.	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.	0.671
ENSRBIP00000003802	ENSRBIP00000004747	ENSRBIP00000003802	ENSRBIP00000004747	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.801
ENSRBIP00000003802	ENSRBIP00000012514	ENSRBIP00000003802	ENSRBIP00000012514	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.804