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MAPK1 MAPK1 LOC108524569 LOC108524569 PCSK4 PCSK4 YBX1 YBX1 LOC108545049 LOC108545049 FURIN FURIN RBL1 RBL1 HDAC1 HDAC1 ENSRBIP00000021679 ENSRBIP00000021679 CCNQ CCNQ ENSRBIP00000020228 ENSRBIP00000020228 CCNT1 CCNT1 CCNT2 CCNT2 SMAD4 SMAD4 CCNC CCNC ENSRBIP00000018271 ENSRBIP00000018271 WWTR1 WWTR1 LOC108527145 LOC108527145 MEN1 MEN1 TFDP1 TFDP1 ENSRBIP00000012514 ENSRBIP00000012514 SMAD2 SMAD2 RPS27A RPS27A ENSRBIP00000000704 ENSRBIP00000000704 ENSRBIP00000001317 ENSRBIP00000001317 ENSRBIP00000029173 ENSRBIP00000029173 SMAD7 SMAD7 ENSRBIP00000027645 ENSRBIP00000027645 LOC108529358 LOC108529358 ENSRBIP00000008820 ENSRBIP00000008820 COL1A2 COL1A2 UBA52 UBA52 TFDP2 TFDP2 SMAD3 SMAD3 TFDP3 TFDP3 LOC108529634 LOC108529634 TGIF1 TGIF1 LOC108540530 LOC108540530 ENSRBIP00000004747 ENSRBIP00000004747 ENSRBIP00000004187 ENSRBIP00000004187 ENSRBIP00000003802 ENSRBIP00000003802 CCNK CCNK E2F5 E2F5 EP300 EP300 E2F4 E2F4 CDK8 CDK8 SP1 SP1 TGIF2 TGIF2 RNF111 RNF111 MYC MYC CDK9 CDK9 SERPINE1 SERPINE1 MAPK3 MAPK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (724 aa)
YBX1CSD_1 domain-containing protein. (282 aa)
LOC108545049CYCLIN domain-containing protein; Belongs to the cyclin family. (264 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (787 aa)
RBL1RB transcriptional corepressor like 1. (1069 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
ENSRBIP00000021679Uncharacterized protein. (269 aa)
CCNQCyclin N-terminal domain-containing protein. (186 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (725 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (721 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CCNCCyclin C; Belongs to the cyclin family. (265 aa)
ENSRBIP00000018271Hist_deacetyl domain-containing protein. (180 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
LOC108527145Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
MEN1Menin 1. (610 aa)
TFDP1Transcription factor. (410 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSRBIP00000000704Uncharacterized protein. (92 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
SMAD7Mothers against decapentaplegic homolog. (431 aa)
ENSRBIP00000027645Homeobox domain-containing protein. (270 aa)
LOC108529358CSD_1 domain-containing protein. (284 aa)
ENSRBIP00000008820Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (470 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
TFDP2Transcription factor. (429 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
TFDP3Transcription factor. (408 aa)
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
TGIF1TGFB induced factor homeobox 1. (367 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
CCNKCyclin K; Belongs to the cyclin family. (542 aa)
E2F5E2F transcription factor 5. (345 aa)
EP300E1A binding protein p300. (2296 aa)
E2F4E2F transcription factor 4. (415 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (482 aa)
SP1Sp1 transcription factor. (769 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
RNF111Ring finger protein 111. (994 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (429 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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