STRINGSTRING
ENSRBIP00000026615 ENSRBIP00000026615 CLTA CLTA SRC SRC EPHB4 EPHB4 CFL1 CFL1 EFNA4 EFNA4 ARPC4 ARPC4 ACTB ACTB EFNB1 EFNB1 EFNA3 EFNA3 PSEN1 PSEN1 CLTB CLTB EPHA6 EPHA6 EFNB3 EFNB3 MMP9 MMP9 ARPC1B ARPC1B ENSRBIP00000005444 ENSRBIP00000005444 NGEF NGEF ACTRT1 ACTRT1 ENSRBIP00000005991 ENSRBIP00000005991 FYN FYN EFNA2 EFNA2 MYL9 MYL9 ACTR3B ACTR3B DSTN DSTN SDCBP2 SDCBP2 ARPC5 ARPC5 ENSRBIP00000009998 ENSRBIP00000009998 LIMK1 LIMK1 ROCK1 ROCK1 PTK2 PTK2 ACTL7B ACTL7B EPHB3 EPHB3 AP2A2 AP2A2 MYL6 MYL6 LOC108515802 LOC108515802 FNDC3B FNDC3B ADAM10 ADAM10 ENSRBIP00000012040 ENSRBIP00000012040 ARPC3 ARPC3 FMN2 FMN2 ENSRBIP00000015006 ENSRBIP00000015006 NCSTN NCSTN ENSRBIP00000015347 ENSRBIP00000015347 SDCBP SDCBP AP2B1 AP2B1 ENSRBIP00000016224 ENSRBIP00000016224 ENSRBIP00000016723 ENSRBIP00000016723 WASL WASL ACTL8 ACTL8 EPHA10 EPHA10 AP2A1 AP2A1 LOC108522676 LOC108522676 ENSRBIP00000018225 ENSRBIP00000018225 ENSRBIP00000018229 ENSRBIP00000018229 EPHA2 EPHA2 TIAM1 TIAM1 APH1B APH1B ENSRBIP00000019284 ENSRBIP00000019284 ARPC1A ARPC1A FNDC3A FNDC3A EPHA4 EPHA4 MYH14 MYH14 MMP2 MMP2 PAK1 PAK1 MYL12B MYL12B PSENEN PSENEN PAK2 PAK2 HRAS HRAS MYH10 MYH10 ACTR3 ACTR3 ENSRBIP00000021960 ENSRBIP00000021960 ENSRBIP00000022666 ENSRBIP00000022666 ARPC2 ARPC2 EFNA5 EFNA5 ENSRBIP00000023765 ENSRBIP00000023765 APH1A APH1A ARHGEF7 ARHGEF7 ENSRBIP00000024420 ENSRBIP00000024420 ENSRBIP00000024768 ENSRBIP00000024768 LIMK2 LIMK2 GIT1 GIT1 EFNB2 EFNB2 RASA1 RASA1 ENSRBIP00000026776 ENSRBIP00000026776 ACTL7A ACTL7A ENSRBIP00000027876 ENSRBIP00000027876 ENSRBIP00000028717 ENSRBIP00000028717 ENSRBIP00000029649 ENSRBIP00000029649 ITSN1 ITSN1 CLTCL1 CLTCL1 ELSPBP1 ELSPBP1 EPHA1 EPHA1 ENSRBIP00000032374 ENSRBIP00000032374 ENSRBIP00000032475 ENSRBIP00000032475 EPHA7 EPHA7 PSEN2 PSEN2 YES1 YES1 ACTG1 ACTG1 FMN1 FMN1 ACTR2 ACTR2 DNM1 DNM1 NCK2 NCK2 ENSRBIP00000035163 ENSRBIP00000035163 ENSRBIP00000035173 ENSRBIP00000035173 ENSRBIP00000035213 ENSRBIP00000035213 ENSRBIP00000035373 ENSRBIP00000035373 AP2S1 AP2S1 LYN LYN EPHA3 EPHA3 VAV3 VAV3 EPHA8 EPHA8 ENSRBIP00000036977 ENSRBIP00000036977 ARHGEF28 ARHGEF28 CDC42 CDC42 ENSRBIP00000037737 ENSRBIP00000037737 MYH9 MYH9 CLTC CLTC GRIN1 GRIN1 ARPC5L ARPC5L MYH11 MYH11 EPHA5 EPHA5 GRIN2B GRIN2B EFNA1 EFNA1 SDC2 SDC2 EPHB6 EPHB6 ROCK2 ROCK2 EPHB1 EPHB1 EPHB2 EPHB2 KALRN KALRN LOC108526895 LOC108526895 ENSRBIP00000000419 ENSRBIP00000000419 LOC108533552 LOC108533552 CFL2 CFL2 VAV2 VAV2 LOC108530360 LOC108530360 AP2M1 AP2M1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSRBIP00000026615Uncharacterized protein. (185 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
SRCTyrosine-protein kinase. (627 aa)
EPHB4EPH receptor B4. (987 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (189 aa)
EFNA4Ephrin A4; Belongs to the ephrin family. (201 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (189 aa)
ACTBActin beta. (379 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
EFNA3Ephrin A3; Belongs to the ephrin family. (238 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (432 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
EPHA6EPH receptor A6. (1130 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
MMP9Matrix metallopeptidase 9. (703 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (375 aa)
ENSRBIP00000005444PDZ domain-containing protein. (212 aa)
NGEFNeuronal guanine nucleotide exchange factor. (704 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
ENSRBIP00000005991Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (170 aa)
FYNTyrosine-protein kinase. (537 aa)
EFNA2Uncharacterized protein. (159 aa)
MYL9Myosin light chain 9. (172 aa)
ACTR3BActin related protein 3B; Belongs to the actin family. (423 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (146 aa)
SDCBP2Syndecan binding protein 2. (292 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ENSRBIP00000009998Uncharacterized protein. (131 aa)
LIMK1LIM domain kinase 1. (677 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1341 aa)
PTK2Protein tyrosine kinase 2. (1078 aa)
ACTL7BActin like 7B; Belongs to the actin family. (399 aa)
EPHB3EPH receptor B3. (1008 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (894 aa)
MYL6Uncharacterized protein. (226 aa)
LOC108515802Uncharacterized protein. (139 aa)
FNDC3BFibronectin type III domain containing 3B. (1178 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
ENSRBIP00000012040PDZ domain-containing protein. (305 aa)
ARPC3Uncharacterized protein. (134 aa)
FMN2Formin 2. (1620 aa)
ENSRBIP00000015006Uncharacterized protein. (131 aa)
NCSTNNicastrin. (709 aa)
ENSRBIP00000015347Uncharacterized protein. (182 aa)
SDCBPSyndecan binding protein. (329 aa)
AP2B1AP complex subunit beta. (951 aa)
ENSRBIP00000016224Uncharacterized protein. (184 aa)
ENSRBIP00000016723Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (164 aa)
WASLWASP like actin nucleation promoting factor. (504 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
EPHA10EPH receptor A10. (974 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
LOC108522676Protein kinase domain-containing protein. (299 aa)
ENSRBIP00000018225ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (125 aa)
ENSRBIP00000018229Uncharacterized protein. (145 aa)
EPHA2EPH receptor A2. (1036 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1591 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
ENSRBIP00000019284Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (169 aa)
ARPC1AActin related protein 2/3 complex subunit 1A. (279 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
EPHA4EPH receptor A4. (978 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1869 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
MYL12BUncharacterized protein. (172 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
PAK2Non-specific serine/threonine protein kinase. (539 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (368 aa)
ENSRBIP00000021960Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (137 aa)
ENSRBIP00000022666Uncharacterized protein. (379 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
ENSRBIP00000023765Uncharacterized protein. (330 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (755 aa)
ENSRBIP00000024420Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa)
ENSRBIP00000024768Uncharacterized protein; Belongs to the actin family. (156 aa)
LIMK2LIM domain kinase 2. (639 aa)
GIT1GIT ArfGAP 1. (817 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (312 aa)
RASA1RAS p21 protein activator 1. (1016 aa)
ENSRBIP00000026776Uncharacterized protein. (147 aa)
ACTL7AActin like 7A; Belongs to the actin family. (395 aa)
ENSRBIP00000027876Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (353 aa)
ENSRBIP00000028717Uncharacterized protein. (173 aa)
ENSRBIP00000029649DH domain-containing protein. (251 aa)
ITSN1Intersectin 1. (1720 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1583 aa)
ELSPBP1Epididymal sperm binding protein 1. (223 aa)
EPHA1EPH receptor A1. (963 aa)
ENSRBIP00000032374Uncharacterized protein. (151 aa)
ENSRBIP00000032475Myosin N-terminal SH3-like domain-containing protein. (161 aa)
EPHA7EPH receptor A7. (985 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
YES1Tyrosine-protein kinase. (480 aa)
ACTG1Actin gamma 1. (377 aa)
FMN1Formin 1. (1256 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (863 aa)
NCK2Cytoplasmic protein. (380 aa)
ENSRBIP00000035163B2-adapt-app_C domain-containing protein. (224 aa)
ENSRBIP00000035173Uncharacterized protein. (96 aa)
ENSRBIP00000035213Uncharacterized protein; Belongs to the actin family. (362 aa)
ENSRBIP00000035373Uncharacterized protein. (225 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
LYNTyrosine-protein kinase. (512 aa)
EPHA3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (303 aa)
VAV3Uncharacterized protein. (287 aa)
EPHA8EPH receptor A8. (987 aa)
ENSRBIP00000036977Protein kinase domain-containing protein. (68 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1685 aa)
CDC42Uncharacterized protein. (191 aa)
ENSRBIP00000037737annotation not available (191 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1681 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2018 aa)
EPHA5EPH receptor A5. (1038 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (156 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
EPHB6EPH receptor B6. (1018 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1387 aa)
EPHB1EPH receptor B1. (984 aa)
EPHB2EPH receptor B2. (1082 aa)
KALRNKalirin RhoGEF kinase. (2940 aa)
LOC108526895Eph LBD domain-containing protein. (271 aa)
ENSRBIP00000000419Uncharacterized protein. (191 aa)
LOC108533552Uncharacterized protein. (177 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (165 aa)
VAV2Vav guanine nucleotide exchange factor 2. (783 aa)
LOC108530360Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (458 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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