Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATM | COP1 | ENSRBIP00000020338 | ENSRBIP00000041867 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | COP1 E3 ubiquitin ligase. | 0.699 |
| ATM | ENSRBIP00000001317 | ENSRBIP00000020338 | ENSRBIP00000001317 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Ubiquitin-like domain-containing protein. | 0.409 |
| ATM | ENSRBIP00000003802 | ENSRBIP00000020338 | ENSRBIP00000003802 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Ubiquitin-like domain-containing protein. | 0.409 |
| ATM | ENSRBIP00000004187 | ENSRBIP00000020338 | ENSRBIP00000004187 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Ubiquitin-like domain-containing protein. | 0.409 |
| ATM | ENSRBIP00000020228 | ENSRBIP00000020338 | ENSRBIP00000020228 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Uncharacterized protein. | 0.717 |
| ATM | ENSRBIP00000029173 | ENSRBIP00000020338 | ENSRBIP00000029173 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Ubiquitin-like domain-containing protein. | 0.409 |
| ATM | RPS27A | ENSRBIP00000020338 | ENSRBIP00000000621 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Ubiquitin-like domain-containing protein. | 0.409 |
| ATM | TP53 | ENSRBIP00000020338 | ENSRBIP00000028632 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.998 |
| COP1 | ATM | ENSRBIP00000041867 | ENSRBIP00000020338 | COP1 E3 ubiquitin ligase. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.699 |
| COP1 | ENSRBIP00000001317 | ENSRBIP00000041867 | ENSRBIP00000001317 | COP1 E3 ubiquitin ligase. | Ubiquitin-like domain-containing protein. | 0.413 |
| COP1 | ENSRBIP00000003802 | ENSRBIP00000041867 | ENSRBIP00000003802 | COP1 E3 ubiquitin ligase. | Ubiquitin-like domain-containing protein. | 0.413 |
| COP1 | ENSRBIP00000004187 | ENSRBIP00000041867 | ENSRBIP00000004187 | COP1 E3 ubiquitin ligase. | Ubiquitin-like domain-containing protein. | 0.413 |
| COP1 | ENSRBIP00000020228 | ENSRBIP00000041867 | ENSRBIP00000020228 | COP1 E3 ubiquitin ligase. | Uncharacterized protein. | 0.617 |
| COP1 | ENSRBIP00000029173 | ENSRBIP00000041867 | ENSRBIP00000029173 | COP1 E3 ubiquitin ligase. | Ubiquitin-like domain-containing protein. | 0.413 |
| COP1 | PSME4 | ENSRBIP00000041867 | ENSRBIP00000035051 | COP1 E3 ubiquitin ligase. | Proteasome activator subunit 4. | 0.445 |
| COP1 | RPS27A | ENSRBIP00000041867 | ENSRBIP00000000621 | COP1 E3 ubiquitin ligase. | Ubiquitin-like domain-containing protein. | 0.413 |
| COP1 | TP53 | ENSRBIP00000041867 | ENSRBIP00000028632 | COP1 E3 ubiquitin ligase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.881 |
| ENSRBIP00000000223 | ENSRBIP00000001317 | ENSRBIP00000000223 | ENSRBIP00000001317 | Proteasome endopeptidase complex. | Ubiquitin-like domain-containing protein. | 0.675 |
| ENSRBIP00000000223 | ENSRBIP00000001324 | ENSRBIP00000000223 | ENSRBIP00000001324 | Proteasome endopeptidase complex. | Uncharacterized protein. | 0.983 |
| ENSRBIP00000000223 | ENSRBIP00000003285 | ENSRBIP00000000223 | ENSRBIP00000003285 | Proteasome endopeptidase complex. | Uncharacterized protein. | 0.819 |
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