85 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PLXNC1	Plexin C1. (1568 aa)
	CFL2	Cofilin 2; Belongs to the actin-binding proteins ADF family. (165 aa)
	RND1	Rho family GTPase 1. (232 aa)
	CFL1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (189 aa)
	SEMA3G	Semaphorin 3G; Belongs to the semaphorin family. (782 aa)
	RHOB	Ras homolog family member B. (196 aa)
	HSP90AB1-2	HATPase_c domain-containing protein. (724 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	ENSRBIP00000006659	Protein kinase domain-containing protein. (275 aa)
	PLXNB3	Plexin B3. (1909 aa)
	SEMA4B	Semaphorin 4B; Belongs to the semaphorin family. (845 aa)
	MYL9	Myosin light chain 9. (172 aa)
	DSTN	Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (146 aa)
	ENSRBIP00000009632	Uncharacterized protein. (60 aa)
	ENSRBIP00000009998	Uncharacterized protein. (131 aa)
	LIMK1	LIM domain kinase 1. (677 aa)
	ROCK1	Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1341 aa)
	DPYSL4	Dihydropyrimidinase like 4. (675 aa)
	MYL6	Uncharacterized protein. (226 aa)
	LOC108515802	Uncharacterized protein. (139 aa)
	PLXNB2	Plexin B2. (1591 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (307 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1281 aa)
	SEMA6B	Semaphorin 6B; Belongs to the semaphorin family. (649 aa)
	DPYSL5	Dihydropyrimidinase like 5. (565 aa)
	PLXNA1	Plexin A1. (1864 aa)
	SEMA3B	Semaphorin 3B; Belongs to the semaphorin family. (754 aa)
	FARP2	FERM, ARH/RhoGEF and pleckstrin domain protein 2. (602 aa)
	LOC108522676	Protein kinase domain-containing protein. (299 aa)
	ENSRBIP00000018225	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (125 aa)
	SEMA7A	Semaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa)
	SEMA5A	Semaphorin 5A. (1035 aa)
	MYH14	Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1869 aa)
	LOC108537061	HATPase_c domain-containing protein. (384 aa)
	PAK1	Non-specific serine/threonine protein kinase. (555 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (862 aa)
	PAK2	Non-specific serine/threonine protein kinase. (539 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (937 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	PLXND1	Plexin D1. (1884 aa)
	MYH10	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
	SEMA3E	Semaphorin 3E; Belongs to the semaphorin family. (741 aa)
	PLXNA3	Plexin A3. (1876 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	ENSRBIP00000022670	Uncharacterized protein. (281 aa)
	PLXNA2	Plexin A2. (1894 aa)
	ITGA1	Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	ARHGEF11	Rho guanine nucleotide exchange factor 11. (1561 aa)
	LIMK2	LIM domain kinase 2. (639 aa)
	ARHGEF12	Rho guanine nucleotide exchange factor 12. (1536 aa)
	PLXNA4	Plexin A4. (1894 aa)
	ENSRBIP00000024991	HATPase_c domain-containing protein. (571 aa)
	SEMA4A	Semaphorin 4A; Belongs to the semaphorin family. (760 aa)
	PKHD1L1	PKHD1 like 1. (4190 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (231 aa)
	DPYSL2	Dihydropyrimidinase like 2. (677 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	ENSRBIP00000032374	Uncharacterized protein. (151 aa)
	ENSRBIP00000032475	Myosin N-terminal SH3-like domain-containing protein. (161 aa)
	HSP90AA1	Heat shock protein 90 alpha family class A member 1. (686 aa)
	MET	MET proto-oncogene, receptor tyrosine kinase. (1383 aa)
	ENSRBIP00000034107	HATPase_c domain-containing protein. (638 aa)
	RHOC	Ras homolog family member C. (193 aa)
	CD72	CD72 molecule. (359 aa)
	CRMP1	Collapsin response mediator protein 1. (668 aa)
	PLXNB1	Plexin B1. (2130 aa)
	SEMA6C	Semaphorin 6C; Belongs to the semaphorin family. (961 aa)
	HSP90AB1	HATPase_c domain-containing protein. (701 aa)
	SEMA3A	Semaphorin 3A; Belongs to the semaphorin family. (774 aa)
	ENSRBIP00000038008	HATPase_c domain-containing protein. (695 aa)
	MYH9	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
	MYH11	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2018 aa)
	DPYSL3	Dihydropyrimidinase like 3. (682 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1310 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (1047 aa)
	TYROBP	TYRO protein tyrosine kinase binding protein. (112 aa)
	TLN1	Talin 1. (2562 aa)
	SEMA6D	Semaphorin 6D; Belongs to the semaphorin family. (1086 aa)
	PIP5K1C	Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (376 aa)
	RRAS	RAS related. (218 aa)
	PKHD1	PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4094 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1387 aa)
	TLN2	Talin 2. (2536 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP35	FYN	ENSRBIP00000012649	ENSRBIP00000006312	Rho GTPase activating protein 35.	Tyrosine-protein kinase.	0.579
ARHGAP35	MET	ENSRBIP00000012649	ENSRBIP00000033873	Rho GTPase activating protein 35.	MET proto-oncogene, receptor tyrosine kinase.	0.695
ARHGAP35	PLXNB1	ENSRBIP00000012649	ENSRBIP00000035689	Rho GTPase activating protein 35.	Plexin B1.	0.421
ARHGAP35	PLXNB2	ENSRBIP00000012649	ENSRBIP00000011304	Rho GTPase activating protein 35.	Plexin B2.	0.403
ARHGAP35	RHOB	ENSRBIP00000012649	ENSRBIP00000005292	Rho GTPase activating protein 35.	Ras homolog family member B.	0.919
ARHGAP35	RHOC	ENSRBIP00000012649	ENSRBIP00000034378	Rho GTPase activating protein 35.	Ras homolog family member C.	0.955
ARHGAP35	RND1	ENSRBIP00000012649	ENSRBIP00000001719	Rho GTPase activating protein 35.	Rho family GTPase 1.	0.867
ARHGAP35	ROCK1	ENSRBIP00000012649	ENSRBIP00000010192	Rho GTPase activating protein 35.	Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.426
ARHGAP35	SEMA4D	ENSRBIP00000012649	ENSRBIP00000021331	Rho GTPase activating protein 35.	Semaphorin 4D; Belongs to the semaphorin family.	0.564
ARHGEF11	ARHGEF12	ENSRBIP00000024851	ENSRBIP00000024903	Rho guanine nucleotide exchange factor 11.	Rho guanine nucleotide exchange factor 12.	0.941
ARHGEF11	ERBB2	ENSRBIP00000024851	ENSRBIP00000032145	Rho guanine nucleotide exchange factor 11.	Receptor protein-tyrosine kinase.	0.435
ARHGEF11	MET	ENSRBIP00000024851	ENSRBIP00000033873	Rho guanine nucleotide exchange factor 11.	MET proto-oncogene, receptor tyrosine kinase.	0.452
ARHGEF11	PLXNB1	ENSRBIP00000024851	ENSRBIP00000035689	Rho guanine nucleotide exchange factor 11.	Plexin B1.	0.856
ARHGEF11	PLXNB2	ENSRBIP00000024851	ENSRBIP00000011304	Rho guanine nucleotide exchange factor 11.	Plexin B2.	0.954
ARHGEF11	PLXNB3	ENSRBIP00000024851	ENSRBIP00000006772	Rho guanine nucleotide exchange factor 11.	Plexin B3.	0.709
ARHGEF11	RHOB	ENSRBIP00000024851	ENSRBIP00000005292	Rho guanine nucleotide exchange factor 11.	Ras homolog family member B.	0.813
ARHGEF11	RHOC	ENSRBIP00000024851	ENSRBIP00000034378	Rho guanine nucleotide exchange factor 11.	Ras homolog family member C.	0.934
ARHGEF11	RND1	ENSRBIP00000024851	ENSRBIP00000001719	Rho guanine nucleotide exchange factor 11.	Rho family GTPase 1.	0.717
ARHGEF11	ROCK1	ENSRBIP00000024851	ENSRBIP00000010192	Rho guanine nucleotide exchange factor 11.	Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.485
ARHGEF11	ROCK2	ENSRBIP00000024851	ENSRBIP00000042918	Rho guanine nucleotide exchange factor 11.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.550