60 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RXRA	Retinoid X receptor alpha. (492 aa)
	NRBP1	Nuclear receptor binding protein 1. (543 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (298 aa)
	ENSRBIP00000037171	Uncharacterized protein. (260 aa)
	HNF4G	Hepatocyte nuclear factor 4 gamma. (455 aa)
	C1orf56	Chromosome 1 open reading frame 56. (342 aa)
	NR0B1	Nuclear receptor subfamily 0 group B member 1. (470 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (441 aa)
	NR1I2	Nuclear receptor subfamily 1 group I member 2. (472 aa)
	NCOR1	Nuclear receptor corepressor 1. (2441 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (613 aa)
	RORB	RAR related orphan receptor B. (475 aa)
	NR1I3	Nuclear receptor subfamily 1 group I member 3. (357 aa)
	NR2E3	Nuclear receptor subfamily 2 group E member 3. (425 aa)
	ENSRBIP00000033019	Uncharacterized protein. (252 aa)
	RXRB	Retinoid X receptor beta. (508 aa)
	RXRG	Retinoid X receptor gamma. (463 aa)
	PGR	Progesterone receptor. (935 aa)
	NCOR2	Nuclear receptor corepressor 2. (2488 aa)
	ENSRBIP00000028880	Uncharacterized protein. (375 aa)
	THRA	Thyroid hormone receptor alpha. (524 aa)
	CEP55	Centrosomal protein 55. (487 aa)
	NR0B2	Nuclear receptor subfamily 0 group B member 2. (257 aa)
	ESR2	Estrogen receptor 2. (530 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (729 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	NR4A3	Nuclear receptor subfamily 4 group A member 3. (637 aa)
	NR2C2AP	Nuclear receptor 2C2 associated protein. (167 aa)
	ENSRBIP00000023025	Uncharacterized protein. (387 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (461 aa)
	NR5A1	Nuclear receptor subfamily 5 group A member 1. (461 aa)
	ESRRA	Uncharacterized protein. (400 aa)
	NR6A1	Nuclear receptor subfamily 6 group A member 1. (480 aa)
	NR2C1	Nuclear receptor subfamily 2 group C member 1. (604 aa)
	LOC108522656	NR LBD domain-containing protein. (344 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (481 aa)
	PPARG-2	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (217 aa)
	NR3C2	Nuclear receptor subfamily 3 group C member 2. (867 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2. (579 aa)
	NR2E1	Nuclear receptor subfamily 2 group E member 1. (421 aa)
	VDR	Vitamin D receptor. (477 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1547 aa)
	NR3C1	Nuclear receptor subfamily 3 group C member 1. (778 aa)
	NR4A2	Nuclear receptor subfamily 4 group A member 2. (598 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (468 aa)
	ESRRB	Estrogen related receptor beta. (500 aa)
	RARG	Uncharacterized protein. (456 aa)
	NR2C2	Nuclear receptor subfamily 2 group C member 2. (629 aa)
	ESRRG	Estrogen related receptor gamma. (470 aa)
	RARB	Retinoic acid receptor beta. (448 aa)
	RARA	Retinoic acid receptor alpha. (478 aa)
	RORC	RAR related orphan receptor C. (519 aa)
	NR5A2	Nuclear receptor subfamily 5 group A member 2. (541 aa)
	NR2F6	Nuclear receptor subfamily 2 group F member 6. (388 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (441 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	THRB	Thyroid hormone receptor beta. (476 aa)
	NRBF2	Nuclear receptor binding factor 2. (289 aa)
	RORA	RAR related orphan receptor A. (555 aa)
	CCDC134	Coiled-coil domain containing 134. (229 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSRBIP00000023025	MED1	ENSRBIP00000023025	ENSRBIP00000014931	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.649
ENSRBIP00000023025	NCOR1	ENSRBIP00000023025	ENSRBIP00000035056	Uncharacterized protein.	Nuclear receptor corepressor 1.	0.727
ENSRBIP00000023025	NCOR2	ENSRBIP00000023025	ENSRBIP00000029297	Uncharacterized protein.	Nuclear receptor corepressor 2.	0.629
ENSRBIP00000023025	NR1D2	ENSRBIP00000023025	ENSRBIP00000017218	Uncharacterized protein.	Nuclear receptor subfamily 1 group D member 2.	0.541
ENSRBIP00000023025	RARA	ENSRBIP00000023025	ENSRBIP00000012179	Uncharacterized protein.	Retinoic acid receptor alpha.	0.658
ENSRBIP00000023025	RARB	ENSRBIP00000023025	ENSRBIP00000011563	Uncharacterized protein.	Retinoic acid receptor beta.	0.468
ENSRBIP00000023025	RXRA	ENSRBIP00000023025	ENSRBIP00000038762	Uncharacterized protein.	Retinoid X receptor alpha.	0.725
ENSRBIP00000023025	RXRB	ENSRBIP00000023025	ENSRBIP00000031209	Uncharacterized protein.	Retinoid X receptor beta.	0.715
ENSRBIP00000023025	RXRG	ENSRBIP00000023025	ENSRBIP00000030991	Uncharacterized protein.	Retinoid X receptor gamma.	0.762
ENSRBIP00000028880	ESRRB	ENSRBIP00000028880	ENSRBIP00000007907	Uncharacterized protein.	Estrogen related receptor beta.	0.488
ENSRBIP00000028880	ESRRG	ENSRBIP00000028880	ENSRBIP00000009410	Uncharacterized protein.	Estrogen related receptor gamma.	0.585
ENSRBIP00000028880	MED1	ENSRBIP00000028880	ENSRBIP00000014931	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.450
ENSRBIP00000028880	NCOR1	ENSRBIP00000028880	ENSRBIP00000035056	Uncharacterized protein.	Nuclear receptor corepressor 1.	0.581
ENSRBIP00000028880	NCOR2	ENSRBIP00000028880	ENSRBIP00000029297	Uncharacterized protein.	Nuclear receptor corepressor 2.	0.538
ENSRBIP00000028880	NR0B1	ENSRBIP00000028880	ENSRBIP00000036010	Uncharacterized protein.	Nuclear receptor subfamily 0 group B member 1.	0.403
ESR1	ESR2	ENSRBIP00000002017	ENSRBIP00000026772	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor 2.	0.995
ESR1	LOC108522656	ENSRBIP00000002017	ENSRBIP00000018300	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	NR LBD domain-containing protein.	0.703
ESR1	MED1	ENSRBIP00000002017	ENSRBIP00000014931	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.992
ESR1	NCOR1	ENSRBIP00000002017	ENSRBIP00000035056	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor corepressor 1.	0.989
ESR1	NCOR2	ENSRBIP00000002017	ENSRBIP00000029297	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor corepressor 2.	0.889