STRINGSTRING
ENSRBIP00000000419 ENSRBIP00000000419 CFL2 CFL2 LOC108530360 LOC108530360 SRC SRC EPHB4 EPHB4 CFL1 CFL1 ARPC4 ARPC4 ACTB ACTB EFNB1 EFNB1 EFNB3 EFNB3 ARPC1B ARPC1B ACTRT1 ACTRT1 ENSRBIP00000005991 ENSRBIP00000005991 FYN FYN ACTR3B ACTR3B DSTN DSTN ARPC5 ARPC5 LIMK1 LIMK1 ROCK1 ROCK1 PTK2 PTK2 ACTL7B ACTL7B EPHB3 EPHB3 FNDC3B FNDC3B ARPC3 ARPC3 FMN2 FMN2 ENSRBIP00000015006 ENSRBIP00000015006 ENSRBIP00000015347 ENSRBIP00000015347 ENSRBIP00000016224 ENSRBIP00000016224 ENSRBIP00000016723 ENSRBIP00000016723 WASL WASL ACTL8 ACTL8 ENSRBIP00000018225 ENSRBIP00000018225 TIAM1 TIAM1 ENSRBIP00000019284 ENSRBIP00000019284 ARPC1A ARPC1A FNDC3A FNDC3A PAK1 PAK1 HRAS HRAS ACTR3 ACTR3 ENSRBIP00000021960 ENSRBIP00000021960 ENSRBIP00000022666 ENSRBIP00000022666 ARPC2 ARPC2 ENSRBIP00000023765 ENSRBIP00000023765 ENSRBIP00000024420 ENSRBIP00000024420 ENSRBIP00000024768 ENSRBIP00000024768 LIMK2 LIMK2 EFNB2 EFNB2 RASA1 RASA1 ENSRBIP00000026615 ENSRBIP00000026615 ACTL7A ACTL7A ENSRBIP00000027876 ENSRBIP00000027876 ENSRBIP00000028717 ENSRBIP00000028717 ITSN1 ITSN1 YES1 YES1 ACTG1 ACTG1 FMN1 FMN1 ACTR2 ACTR2 ENSRBIP00000035173 ENSRBIP00000035173 ENSRBIP00000035213 ENSRBIP00000035213 ENSRBIP00000035373 ENSRBIP00000035373 LYN LYN ENSRBIP00000036977 ENSRBIP00000036977 ARHGEF28 ARHGEF28 CDC42 CDC42 ENSRBIP00000037737 ENSRBIP00000037737 GRIN1 GRIN1 ARPC5L ARPC5L GRIN2B GRIN2B SDC2 SDC2 EPHB6 EPHB6 ROCK2 ROCK2 EPHB1 EPHB1 EPHB2 EPHB2 KALRN KALRN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSRBIP00000000419Uncharacterized protein. (191 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (165 aa)
LOC108530360Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
SRCTyrosine-protein kinase. (627 aa)
EPHB4EPH receptor B4. (987 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (189 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (189 aa)
ACTBActin beta. (379 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (375 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
ENSRBIP00000005991Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (170 aa)
FYNTyrosine-protein kinase. (537 aa)
ACTR3BActin related protein 3B; Belongs to the actin family. (423 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (146 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
LIMK1LIM domain kinase 1. (677 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1341 aa)
PTK2Protein tyrosine kinase 2. (1078 aa)
ACTL7BActin like 7B; Belongs to the actin family. (399 aa)
EPHB3EPH receptor B3. (1008 aa)
FNDC3BFibronectin type III domain containing 3B. (1178 aa)
ARPC3Uncharacterized protein. (134 aa)
FMN2Formin 2. (1620 aa)
ENSRBIP00000015006Uncharacterized protein. (131 aa)
ENSRBIP00000015347Uncharacterized protein. (182 aa)
ENSRBIP00000016224Uncharacterized protein. (184 aa)
ENSRBIP00000016723Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (164 aa)
WASLWASP like actin nucleation promoting factor. (504 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
ENSRBIP00000018225ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (125 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1591 aa)
ENSRBIP00000019284Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (169 aa)
ARPC1AActin related protein 2/3 complex subunit 1A. (279 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (368 aa)
ENSRBIP00000021960Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (137 aa)
ENSRBIP00000022666Uncharacterized protein. (379 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
ENSRBIP00000023765Uncharacterized protein. (330 aa)
ENSRBIP00000024420Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa)
ENSRBIP00000024768Uncharacterized protein; Belongs to the actin family. (156 aa)
LIMK2LIM domain kinase 2. (639 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (312 aa)
RASA1RAS p21 protein activator 1. (1016 aa)
ENSRBIP00000026615Uncharacterized protein. (185 aa)
ACTL7AActin like 7A; Belongs to the actin family. (395 aa)
ENSRBIP00000027876Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (353 aa)
ENSRBIP00000028717Uncharacterized protein. (173 aa)
ITSN1Intersectin 1. (1720 aa)
YES1Tyrosine-protein kinase. (480 aa)
ACTG1Actin gamma 1. (377 aa)
FMN1Formin 1. (1256 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
ENSRBIP00000035173Uncharacterized protein. (96 aa)
ENSRBIP00000035213Uncharacterized protein; Belongs to the actin family. (362 aa)
ENSRBIP00000035373Uncharacterized protein. (225 aa)
LYNTyrosine-protein kinase. (512 aa)
ENSRBIP00000036977Protein kinase domain-containing protein. (68 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1685 aa)
CDC42Uncharacterized protein. (191 aa)
ENSRBIP00000037737annotation not available (191 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
EPHB6EPH receptor B6. (1018 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1387 aa)
EPHB1EPH receptor B1. (984 aa)
EPHB2EPH receptor B2. (1082 aa)
KALRNKalirin RhoGEF kinase. (2940 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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