STRINGSTRING
KLF4 KLF4 LOC108536266 LOC108536266 LEP LEP LOC108536264 LOC108536264 ENSRBIP00000039373 ENSRBIP00000039373 ACHE ACHE MBOAT4 MBOAT4 SEC11A SEC11A GHRL GHRL ENSRBIP00000029471 ENSRBIP00000029471 ENSRBIP00000029052 ENSRBIP00000029052 KLF2 KLF2 FAP FAP GCG GCG SPCS3 SPCS3 INS INS SPCS1 SPCS1 IGF1 IGF1 ENSRBIP00000008355 ENSRBIP00000008355 PLA2G7 PLA2G7 CRHR2 CRHR2 PCSK1 PCSK1 SEC11C SEC11C BCHE BCHE ENSRBIP00000002418 ENSRBIP00000002418 ENSRBIP00000001604 ENSRBIP00000001604
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KLF4Kruppel like factor 4. (511 aa)
LOC108536266Uncharacterized protein. (217 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
LOC108536264Uncharacterized protein. (217 aa)
ENSRBIP00000039373Uncharacterized protein. (215 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (631 aa)
MBOAT4Membrane bound O-acyltransferase domain containing 4; Belongs to the membrane-bound acyltransferase family. (439 aa)
SEC11ASignal peptidase complex catalytic subunit SEC11. (185 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
ENSRBIP00000029471Uncharacterized protein. (107 aa)
ENSRBIP00000029052Uncharacterized protein. (184 aa)
KLF2Uncharacterized protein. (194 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
GCGGlucagon. (180 aa)
SPCS3Signal peptidase complex subunit 3. (180 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
SPCS1Signal peptidase complex subunit 1. (169 aa)
IGF1Insulin like growth factor 1. (208 aa)
ENSRBIP00000008355Uncharacterized protein. (216 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (439 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa)
SEC11CSignal peptidase complex catalytic subunit SEC11. (192 aa)
BCHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (602 aa)
ENSRBIP00000002418Uncharacterized protein. (168 aa)
ENSRBIP00000001604Uncharacterized protein. (142 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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