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GNB4 GNB4 ADCY6 ADCY6 RAPGEF5 RAPGEF5 GNA11 GNA11 CACNA1A CACNA1A KCNJ11 KCNJ11 RAP1A RAP1A PRKAR2A PRKAR2A KCNG2 KCNG2 GNB2 GNB2 AHCYL1 AHCYL1 GNB3 GNB3 GNG4 GNG4 GNG5 GNG5 THAP1 THAP1 GNG11 GNG11 LOC108522831 LOC108522831 THAP7 THAP7 RAPGEFL1 RAPGEFL1 PRKCA PRKCA SLC2A1 SLC2A1 CACNB2 CACNB2 CACNA1D CACNA1D GNG2 GNG2 ITPR2 ITPR2 ITPR1 ITPR1 PRKAR2B PRKAR2B KCNB1 KCNB1 PLCB3 PLCB3 ADCY8 ADCY8 SNAP25 SNAP25 KCNC2 KCNC2 SYT5 SYT5 GNA15 GNA15 GNG3 GNG3 CACNA2D1 CACNA2D1 GCG GCG FAP FAP GLP1R GLP1R GNAI2 GNAI2 ENSRBIP00000030120 ENSRBIP00000030120 CACNA1E CACNA1E GNG12 GNG12 THAP6 THAP6 GNB1 GNB1 GNG8 GNG8 STX1A STX1A ENSRBIP00000034184 ENSRBIP00000034184 INS INS KCNS3 KCNS3 CACNA1F CACNA1F STXBP1 STXBP1 ADRA2A ADRA2A CACNA1C CACNA1C GNAS GNAS PRKACA PRKACA ENSRBIP00000013012 ENSRBIP00000013012 FFAR1 FFAR1 ENSRBIP00000011770 ENSRBIP00000011770 ACSL3 ACSL3 GNG13 GNG13 GNG7 GNG7 CD36 CD36 GNA14 GNA14 ABCC8 ABCC8 GNAQ GNAQ VAMP2 VAMP2 ITPR3 ITPR3 GNG10 GNG10 RAPGEF4 RAPGEF4 PLCB2 PLCB2 GNGT2 GNGT2 PRKAR1B PRKAR1B CACNB3 CACNB3 CACNA2D2 CACNA2D2 ENSRBIP00000007423 ENSRBIP00000007423 PRKAR1A PRKAR1A IQGAP1 IQGAP1 SLC2A2 SLC2A2 GNB5 GNB5 PRKACB PRKACB ADCY5 ADCY5 PLCB1 PLCB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNB4G protein subunit beta 4. (340 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (638 aa)
GNA11G protein subunit alpha 11. (354 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2305 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (376 aa)
KCNG2Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (427 aa)
GNB2G protein subunit beta 2. (368 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
GNB3G protein subunit beta 3. (340 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
THAP1THAP domain containing 1. (167 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
LOC108522831PH_14 domain-containing protein. (199 aa)
THAP7THAP domain containing 7. (309 aa)
RAPGEFL1Rap guanine nucleotide exchange factor like 1. (667 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (102 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (412 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1210 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
KCNC2Ion_trans domain-containing protein; Belongs to the potassium channel family. (240 aa)
SYT5Synaptotagmin 5. (386 aa)
GNA15G protein subunit alpha 15. (312 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
GCGGlucagon. (180 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
GNAI2G protein subunit alpha i2. (355 aa)
ENSRBIP00000030120Uncharacterized protein. (294 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2298 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
THAP6THAP domain containing 6. (221 aa)
GNB1G protein subunit beta 1. (340 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
ENSRBIP00000034184G protein gamma domain-containing protein. (68 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1818 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (600 aa)
ADRA2AAdrenoceptor alpha 2A. (400 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2066 aa)
GNASGNAS complex locus. (1041 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (235 aa)
ENSRBIP00000013012Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
ENSRBIP00000011770Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (704 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
GNA14G protein subunit alpha 14. (355 aa)
ABCC8ATP binding cassette subfamily C member 8. (1585 aa)
GNAQG protein subunit alpha q. (359 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (62 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (882 aa)
PLCB2Phosphoinositide phospholipase C. (991 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (452 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (485 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1140 aa)
ENSRBIP00000007423Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1630 aa)
SLC2A2MFS domain-containing protein. (115 aa)
GNB5G protein subunit beta 5. (403 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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