80 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NFKBIB	NFKB inhibitor beta. (338 aa)
	KHNYN	KH and NYN domain containing. (678 aa)
	ENSRBIP00000006958	TNF receptor-associated factor. (473 aa)
	NKIRAS1	NFKB inhibitor interacting Ras like 1. (192 aa)
	LOC108526191	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (112 aa)
	UBA52	Ubiquitin-like domain-containing protein. (232 aa)
	NFKB2	Nuclear factor kappa B subunit 2. (906 aa)
	LRRC14	Leucine rich repeat containing 14. (493 aa)
	LRRC34	Leucine rich repeat containing 34. (457 aa)
	NLRP9	NLR family pyrin domain containing 9. (933 aa)
	NLRP13	NLR family pyrin domain containing 13. (1044 aa)
	S100B	S_100 domain-containing protein; Belongs to the S-100 family. (94 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (969 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
	ENSRBIP00000012514	Ubiquitin-like domain-containing protein. (121 aa)
	LRRC74A	Leucine rich repeat containing 74A. (485 aa)
	S100A12	S100 calcium binding protein A12; Belongs to the S-100 family. (90 aa)
	LRRC31	Leucine rich repeat containing 31. (552 aa)
	ENSRBIP00000014363	UBIQUITIN_CONJUGAT_2 domain-containing protein. (128 aa)
	ENSRBIP00000014751	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (105 aa)
	HMGB1	Uncharacterized protein. (181 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa)
	ENSRBIP00000017090	Uncharacterized protein. (120 aa)
	MAP3K20	Mitogen-activated protein kinase kinase kinase 20. (800 aa)
	RELA	Uncharacterized protein. (282 aa)
	NLRP6	NLR family pyrin domain containing 6. (1041 aa)
	ENSRBIP00000019157	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (78 aa)
	ENSRBIP00000020228	Uncharacterized protein. (132 aa)
	LRRC71	Leucine rich repeat containing 71. (559 aa)
	N4BP1	NEDD4 binding protein 1. (895 aa)
	ENSRBIP00000022247	Uncharacterized protein. (70 aa)
	ALPK1	Alpha kinase 1. (1245 aa)
	AGER	Uncharacterized protein. (417 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
	LOC108524569	Ubiquitin-like domain-containing protein. (141 aa)
	IRAK1	Interleukin 1 receptor associated kinase 1. (702 aa)
	NLRX1	NLR family member X1. (972 aa)
	ENSRBIP00000026978	Uncharacterized protein. (179 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
	ENSRBIP00000029173	Ubiquitin-like domain-containing protein. (166 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (537 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
	ENSRBIP00000032381	Uncharacterized protein. (130 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (953 aa)
	USP14	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (542 aa)
	LRRC45	Leucine rich repeat containing 45. (669 aa)
	LOC108528435	Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa)
	NFKBIA	NFKB inhibitor alpha. (317 aa)
	ENSRBIP00000038500	RHD domain-containing protein. (112 aa)
	APP	Amyloid beta precursor protein. (770 aa)
	TAB3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (690 aa)
	LOC108524385	Uncharacterized protein. (348 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
	ENSRBIP00000035735	Uncharacterized protein. (100 aa)
	LOC108528453	Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
	NLRC5	NLR family CARD domain containing 5. (1866 aa)
	NKIRAS2	NFKB inhibitor interacting Ras like 2. (231 aa)
	ENSRBIP00000033992	Uncharacterized protein. (157 aa)
	VWC2	Von Willebrand factor C domain containing 2. (325 aa)
	CCDC71L	Coiled-coil domain containing 71 like. (235 aa)
	ENSRBIP00000033406	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	ENSRBIP00000001317	Ubiquitin-like domain-containing protein. (155 aa)
	TIFA	TRAF interacting protein with forkhead associated domain. (185 aa)
	ENSRBIP00000002911	Uncharacterized protein. (190 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1153 aa)
	TONSL	Tonsoku like, DNA repair protein. (1367 aa)
	ENSRBIP00000003802	Ubiquitin-like domain-containing protein. (84 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (443 aa)
	ENSRBIP00000004187	Ubiquitin-like domain-containing protein. (153 aa)
	ENSRBIP00000004747	Ubiquitin-like domain-containing protein. (128 aa)
	UBE2NL	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
	LOC108540530	Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
	LOC108529634	Ubiquitin-like domain-containing protein. (128 aa)
	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (512 aa)
	HMGB1-2	Uncharacterized protein. (215 aa)
	LOC108520651	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGER	APP	ENSRBIP00000023070	ENSRBIP00000038205	Uncharacterized protein.	Amyloid beta precursor protein.	0.520
AGER	ENSRBIP00000002911	ENSRBIP00000023070	ENSRBIP00000002911	Uncharacterized protein.	Uncharacterized protein.	0.431
AGER	ENSRBIP00000017090	ENSRBIP00000023070	ENSRBIP00000017090	Uncharacterized protein.	Uncharacterized protein.	0.431
AGER	ENSRBIP00000026978	ENSRBIP00000023070	ENSRBIP00000026978	Uncharacterized protein.	Uncharacterized protein.	0.431
AGER	ENSRBIP00000032381	ENSRBIP00000023070	ENSRBIP00000032381	Uncharacterized protein.	Uncharacterized protein.	0.431
AGER	ENSRBIP00000033992	ENSRBIP00000023070	ENSRBIP00000033992	Uncharacterized protein.	Uncharacterized protein.	0.431
AGER	HMGB1	ENSRBIP00000023070	ENSRBIP00000015128	Uncharacterized protein.	Uncharacterized protein.	0.431
AGER	HMGB1-2	ENSRBIP00000023070	ENSRBIP00000005571	Uncharacterized protein.	Uncharacterized protein.	0.431
AGER	S100A12	ENSRBIP00000023070	ENSRBIP00000013885	Uncharacterized protein.	S100 calcium binding protein A12; Belongs to the S-100 family.	0.713
AGER	S100B	ENSRBIP00000023070	ENSRBIP00000011863	Uncharacterized protein.	S_100 domain-containing protein; Belongs to the S-100 family.	0.932
ALPK1	ENSRBIP00000006958	ENSRBIP00000022913	ENSRBIP00000006958	Alpha kinase 1.	TNF receptor-associated factor.	0.474
ALPK1	MAP3K20	ENSRBIP00000022913	ENSRBIP00000017957	Alpha kinase 1.	Mitogen-activated protein kinase kinase kinase 20.	0.419
ALPK1	MAP3K7	ENSRBIP00000022913	ENSRBIP00000005150	Alpha kinase 1.	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.	0.544
ALPK1	TIFA	ENSRBIP00000022913	ENSRBIP00000001963	Alpha kinase 1.	TRAF interacting protein with forkhead associated domain.	0.868
ALPK1	TRAF6	ENSRBIP00000022913	ENSRBIP00000036224	Alpha kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.474
APP	AGER	ENSRBIP00000038205	ENSRBIP00000023070	Amyloid beta precursor protein.	Uncharacterized protein.	0.520
APP	LOC108524385	ENSRBIP00000038205	ENSRBIP00000036734	Amyloid beta precursor protein.	Uncharacterized protein.	0.520
APP	NFKB1	ENSRBIP00000038205	ENSRBIP00000012337	Amyloid beta precursor protein.	Nuclear factor kappa B subunit 1.	0.588
APP	NFKB2	ENSRBIP00000038205	ENSRBIP00000008363	Amyloid beta precursor protein.	Nuclear factor kappa B subunit 2.	0.482
APP	S100B	ENSRBIP00000038205	ENSRBIP00000011863	Amyloid beta precursor protein.	S_100 domain-containing protein; Belongs to the S-100 family.	0.497