STRINGSTRING
IL17RC IL17RC IRAK2 IRAK2 ENSRBIP00000029173 ENSRBIP00000029173 MAP3K8 MAP3K8 MAPK14 MAPK14 IKBKB IKBKB FOSL2 FOSL2 IL25 IL25 MAPK1 MAPK1 IRAK1 IRAK1 LOC108524569 LOC108524569 IL17F IL17F FOS FOS LOC108515310 LOC108515310 CHUK CHUK ENSRBIP00000023060 ENSRBIP00000023060 ENSRBIP00000022247 ENSRBIP00000022247 RELCH RELCH ENSRBIP00000020927 ENSRBIP00000020927 MAP2K6 MAP2K6 ENSRBIP00000020228 ENSRBIP00000020228 ENSRBIP00000010265 ENSRBIP00000010265 MEF2A MEF2A MAP3K20 MAP3K20 MAPKAPK3 MAPKAPK3 NFKB1 NFKB1 TAB2 TAB2 ENSRBIP00000012514 ENSRBIP00000012514 CUL1 CUL1 ATF1 ATF1 RPS6KA3 RPS6KA3 ENSRBIP00000014363 ENSRBIP00000014363 ENSRBIP00000014751 ENSRBIP00000014751 MAP2K1 MAP2K1 IKBKG IKBKG ENSRBIP00000015185 ENSRBIP00000015185 DUSP3 DUSP3 ENSRBIP00000016494 ENSRBIP00000016494 PPP2CB PPP2CB ATF7 ATF7 MAP2K3 MAP2K3 BTRC BTRC MAPK3 MAPK3 RPS27A RPS27A TNIP2 TNIP2 ENSRBIP00000001317 ENSRBIP00000001317 DUSP7 DUSP7 NOD2 NOD2 MAPK10 MAPK10 LOC108544295 LOC108544295 ENSRBIP00000003802 ENSRBIP00000003802 RIPK2 RIPK2 RPS6KA2 RPS6KA2 ENSRBIP00000004187 ENSRBIP00000004187 ENSRBIP00000004747 ENSRBIP00000004747 UBE2NL UBE2NL MAP3K7 MAP3K7 LOC108540530 LOC108540530 LOC108529634 LOC108529634 TAB1 TAB1 LOC108520651 LOC108520651 ELK1 ELK1 PPP2R5D PPP2R5D ENSRBIP00000020047 ENSRBIP00000020047 IL17C IL17C ENSRBIP00000019157 ENSRBIP00000019157 MAPK15 MAPK15 ENSRBIP00000006958 ENSRBIP00000006958 MAPK9 MAPK9 LOC108526191 LOC108526191 PPP2R1B PPP2R1B UBA52 UBA52 VRK3 VRK3 RPS6KA1 RPS6KA1 PPP2R1A PPP2R1A TRAF6 TRAF6 SKP1 SKP1 MAP2K7 MAP2K7 RPS6KA5 RPS6KA5 PPP4R1 PPP4R1 TAB3 TAB3 PPP4R4 PPP4R4 MAPK7 MAPK7 CREM CREM FNBP4 FNBP4 ENSRBIP00000039839 ENSRBIP00000039839 IL17A IL17A ATF2 ATF2 DUSP6 DUSP6 IL17RB IL17RB MAPK11 MAPK11 MAPKAPK2 MAPKAPK2 CREB1 CREB1 CCDC71L CCDC71L LOC108525504 LOC108525504 MEF2C MEF2C ENSRBIP00000033406 ENSRBIP00000033406 IL17RE IL17RE NOD1 NOD1 DUSP4 DUSP4 MAPK8 MAPK8 CREB5 CREB5 MAP2K4 MAP2K4 FBXW11 FBXW11 PPP2CA PPP2CA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL17RCInterleukin 17 receptor C. (787 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (537 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (466 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
IL25Interleukin 25. (161 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (702 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
IL17FInterleukin 17F. (163 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
LOC108515310WRNPLPNID domain-containing protein. (954 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
ENSRBIP00000023060Protein kinase domain-containing protein. (120 aa)
ENSRBIP00000022247Uncharacterized protein. (70 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1216 aa)
ENSRBIP00000020927Uncharacterized protein. (147 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
ENSRBIP00000010265Uncharacterized protein. (161 aa)
MEF2AMyocyte enhancer factor 2A. (511 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (434 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
ATF1Activating transcription factor 1. (269 aa)
RPS6KA3Uncharacterized protein. (66 aa)
ENSRBIP00000014363UBIQUITIN_CONJUGAT_2 domain-containing protein. (128 aa)
ENSRBIP00000014751UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (105 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa)
ENSRBIP00000015185ETS domain-containing protein. (421 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
ENSRBIP00000016494Protein kinase domain-containing protein. (253 aa)
PPP2CBSerine/threonine-protein phosphatase. (304 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (494 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
TNIP2CCHC NOA-type domain-containing protein. (337 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1153 aa)
MAPK10Mitogen-activated protein kinase. (528 aa)
LOC108544295Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (443 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
UBE2NLUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (512 aa)
LOC108520651UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ELK1ETS domain-containing protein. (428 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
ENSRBIP00000020047Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
IL17CInterleukin 17C. (197 aa)
ENSRBIP00000019157UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (78 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
ENSRBIP00000006958TNF receptor-associated factor. (473 aa)
MAPK9Mitogen-activated protein kinase. (407 aa)
LOC108526191UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (112 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
VRK3VRK serine/threonine kinase 3. (479 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
SKP1Uncharacterized protein; Belongs to the SKP1 family. (154 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (414 aa)
RPS6KA5Non-specific serine/threonine protein kinase. (684 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (930 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (690 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (807 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
CREMcAMP responsive element modulator. (330 aa)
FNBP4Formin binding protein 4. (925 aa)
ENSRBIP00000039839Uncharacterized protein; Belongs to the SKP1 family. (129 aa)
IL17AInterleukin 17A. (155 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (429 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
IL17RBInterleukin 17 receptor B. (490 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
MAPKAPK2MAPK activated protein kinase 2. (392 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CCDC71LCoiled-coil domain containing 71 like. (235 aa)
LOC108525504Uncharacterized protein. (70 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
ENSRBIP00000033406UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
IL17REInterleukin 17 receptor E. (673 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
MAPK8Mitogen-activated protein kinase 8. (383 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (503 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (408 aa)
FBXW11F-box and WD repeat domain containing 11. (522 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.