STRINGSTRING
MAPK3 MAPK3 DUSP7 DUSP7 MAPK10 MAPK10 RPS6KA2 RPS6KA2 ELK1 ELK1 PPP2R5D PPP2R5D MAPK9 MAPK9 PPP2R1B PPP2R1B VRK3 VRK3 RPS6KA1 RPS6KA1 PPP2R1A PPP2R1A ENSRBIP00000010265 ENSRBIP00000010265 MEF2A MEF2A ATF1 ATF1 RPS6KA3 RPS6KA3 ENSRBIP00000015185 ENSRBIP00000015185 DUSP3 DUSP3 PPP2CB PPP2CB ATF7 ATF7 MAPK15 MAPK15 ENSRBIP00000020927 ENSRBIP00000020927 RELCH RELCH LOC108515310 LOC108515310 FOS FOS MAPK1 MAPK1 FOSL2 FOSL2 MAPK14 MAPK14 CREB5 CREB5 MAPK8 MAPK8 DUSP4 DUSP4 MEF2C MEF2C LOC108525504 LOC108525504 CREB1 CREB1 MAPKAPK2 MAPKAPK2 MAPK11 MAPK11 DUSP6 DUSP6 ATF2 ATF2 RPS6KA5 RPS6KA5 PPP4R1 PPP4R1 PPP4R4 PPP4R4 MAPK7 MAPK7 CREM CREM FNBP4 FNBP4 PPP2CA PPP2CA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
MAPK10Mitogen-activated protein kinase. (528 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
ELK1ETS domain-containing protein. (428 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
MAPK9Mitogen-activated protein kinase. (407 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
VRK3VRK serine/threonine kinase 3. (479 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
ENSRBIP00000010265Uncharacterized protein. (161 aa)
MEF2AMyocyte enhancer factor 2A. (511 aa)
ATF1Activating transcription factor 1. (269 aa)
RPS6KA3Uncharacterized protein. (66 aa)
ENSRBIP00000015185ETS domain-containing protein. (421 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
PPP2CBSerine/threonine-protein phosphatase. (304 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (494 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
ENSRBIP00000020927Uncharacterized protein. (147 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1216 aa)
LOC108515310WRNPLPNID domain-containing protein. (954 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (503 aa)
MAPK8Mitogen-activated protein kinase 8. (383 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
LOC108525504Uncharacterized protein. (70 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MAPKAPK2MAPK activated protein kinase 2. (392 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (429 aa)
RPS6KA5Non-specific serine/threonine protein kinase. (684 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (930 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (807 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
CREMcAMP responsive element modulator. (330 aa)
FNBP4Formin binding protein 4. (925 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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