STRINGSTRING
RIPK1 RIPK1 SPPL2A SPPL2A TNFRSF1A TNFRSF1A RNF31 RNF31 MADD MADD CLIP3 CLIP3 ULK1 ULK1 ENSRBIP00000006697 ENSRBIP00000006697 RACK1 RACK1 UBA52 UBA52 NFATC4 NFATC4 ENSRBIP00000009378 ENSRBIP00000009378 CFLAR CFLAR SPATA2 SPATA2 TRAF1 TRAF1 STUB1 STUB1 TNF TNF BIRC2 BIRC2 ENSRBIP00000012514 ENSRBIP00000012514 SPPL2B SPPL2B LOC108529634 LOC108529634 LOC108540530 LOC108540530 ENSRBIP00000004747 ENSRBIP00000004747 IKBKE IKBKE ENSRBIP00000004187 ENSRBIP00000004187 ENSRBIP00000003802 ENSRBIP00000003802 BIRC3 BIRC3 OTULIN OTULIN ENSRBIP00000001317 ENSRBIP00000001317 RPS27A RPS27A OTUD7B OTUD7B UBE2D3 UBE2D3 IKBKG IKBKG UBE2D1 UBE2D1 MIB2 MIB2 UBE2D2 UBE2D2 TRADD TRADD TAX1BP1 TAX1BP1 TNFAIP3 TNFAIP3 ENSRBIP00000020228 ENSRBIP00000020228 ENSRBIP00000022961 ENSRBIP00000022961 NAIP NAIP CHUK CHUK ENSRBIP00000024469 ENSRBIP00000024469 CYLD CYLD USP2 USP2 LOC108524569 LOC108524569 FADD FADD IKBKB IKBKB USP4 USP4 ENSRBIP00000029173 ENSRBIP00000029173 TBK1 TBK1 OTULINL OTULINL TRAF2 TRAF2 ULK2 ULK2 OPTN OPTN USP21 USP21 RBCK1 RBCK1 WDR31 WDR31 MAPKAPK2 MAPKAPK2 SHARPIN SHARPIN BIRC7 BIRC7 CLIP4 CLIP4 TMEM198 TMEM198 CASP8 CASP8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIPK1Receptor interacting serine/threonine kinase 1. (672 aa)
SPPL2ASignal peptide peptidase like 2A. (422 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
RNF31Uncharacterized protein. (1072 aa)
MADDMAP kinase activating death domain. (1632 aa)
CLIP3CAP-Gly domain containing linker protein 3. (547 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1044 aa)
ENSRBIP00000006697UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
RACK1Receptor for activated C kinase 1. (330 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
NFATC4Nuclear factor of activated T cells 4. (909 aa)
ENSRBIP00000009378Uncharacterized protein. (115 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
SPATA2Spermatogenesis associated 2. (520 aa)
TRAF1TNF receptor-associated factor. (416 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
SPPL2BSignal peptide peptidase like 2B. (511 aa)
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (352 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
OTUD7BOTU deubiquitinase 7B. (838 aa)
UBE2D3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (960 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
TRADDTNFRSF1A associated via death domain. (248 aa)
TAX1BP1Tax1 binding protein 1. (813 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
ENSRBIP00000022961UBIQUITIN_CONJUGAT_2 domain-containing protein. (122 aa)
NAIPNLR family apoptosis inhibitory protein. (1395 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
ENSRBIP00000024469UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (128 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (948 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (605 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
TBK1TANK binding kinase 1. (681 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (356 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
ULK2Unc-51 like autophagy activating kinase 2. (593 aa)
OPTNOptineurin. (574 aa)
USP21Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (565 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
WDR31WD repeat domain 31. (367 aa)
MAPKAPK2MAPK activated protein kinase 2. (392 aa)
SHARPINSHANK associated RH domain interactor. (384 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
CLIP4CAP-Gly domain containing linker protein family member 4. (705 aa)
TMEM198Transmembrane protein 198. (360 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (542 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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