STRINGSTRING
PCNA PCNA MSH6 MSH6 ENSRBIP00000000510 ENSRBIP00000000510 POLD3 POLD3 LIG1 LIG1 RPA3 RPA3 PMS2 PMS2 POLD2 POLD2 EXO1 EXO1 RPA1 RPA1 POLD4 POLD4 PMS1 PMS1 POLD1 POLD1 MSH2 MSH2 ENSRBIP00000013617 ENSRBIP00000013617 MEIOB MEIOB MLH1 MLH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1305 aa)
ENSRBIP00000000510Uncharacterized protein. (105 aa)
POLD3Uncharacterized protein. (454 aa)
LIG1DNA ligase. (928 aa)
RPA3Replication protein A3. (121 aa)
PMS2PMS1 homolog 2, mismatch repair system component. (572 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
EXO1Exonuclease 1. (827 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
POLD4Uncharacterized protein. (107 aa)
PMS1PMS1 homolog 1, mismatch repair system component. (933 aa)
POLD1DNA polymerase. (1124 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (932 aa)
ENSRBIP00000013617Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (245 aa)
MEIOBMeiosis specific with OB-fold. (449 aa)
MLH1MutL homolog 1. (754 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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