STRINGSTRING
LOC108529634 LOC108529634 ERAS ERAS UBA52 UBA52 FGF1 FGF1 ENSRBIP00000009767 ENSRBIP00000009767 PPP2R1A PPP2R1A FNDC3B FNDC3B ENSRBIP00000011319 ENSRBIP00000011319 ENSRBIP00000012514 ENSRBIP00000012514 FRS3 FRS3 GRB2 GRB2 KRAS KRAS MAPK1 MAPK1 ENSRBIP00000026419 ENSRBIP00000026419 LOC108524569 LOC108524569 FGFR4 FGFR4 HRAS HRAS BRAF BRAF ENSRBIP00000020228 ENSRBIP00000020228 FNDC3A FNDC3A LOC108512216 LOC108512216 MKNK1 MKNK1 PIK3CA PIK3CA FGF19 FGF19 ENSRBIP00000016878 ENSRBIP00000016878 PPP2CB PPP2CB FGF16 FGF16 NRAS NRAS PLCG1 PLCG1 CBL CBL FGF18 FGF18 SOS1 SOS1 ENSRBIP00000032719 ENSRBIP00000032719 FGF17 FGF17 GAB1 GAB1 FGF2 FGF2 FGF6 FGF6 CSDE1 CSDE1 FGF9 FGF9 ENSRBIP00000029173 ENSRBIP00000029173 FRS2 FRS2 FGF8 FGF8 ENSRBIP00000040717 ENSRBIP00000040717 SHC1 SHC1 PPP2CA PPP2CA CSDE1-2 CSDE1-2 FGF23 FGF23 MKNK2 MKNK2 PTPN11 PTPN11 MAPK3 MAPK3 RPS27A RPS27A ENSRBIP00000001317 ENSRBIP00000001317 PIK3R1 PIK3R1 FGF4 FGF4 ENSRBIP00000002079 ENSRBIP00000002079 SRC SRC FGF20 FGF20 ENSRBIP00000003802 ENSRBIP00000003802 ENSRBIP00000004187 ENSRBIP00000004187 KLB KLB ENSRBIP00000004747 ENSRBIP00000004747 LOC108540530 LOC108540530
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
ERASES cell expressed Ras. (233 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ENSRBIP00000009767Uncharacterized protein. (546 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
FNDC3BFibronectin type III domain containing 3B. (1178 aa)
ENSRBIP00000011319Protein kinase domain-containing protein. (265 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
FRS3Fibroblast growth factor receptor substrate 3. (491 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
ENSRBIP00000026419Uncharacterized protein. (249 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
FGFR4Fibroblast growth factor receptor. (749 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (753 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
LOC108512216Uncharacterized protein. (377 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (464 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ENSRBIP00000016878Uncharacterized protein. (251 aa)
PPP2CBSerine/threonine-protein phosphatase. (304 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
CBLCbl proto-oncogene. (802 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1293 aa)
ENSRBIP00000032719SH2 domain-containing protein. (203 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
GAB1GRB2 associated binding protein 1. (722 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (263 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CSDE1Uncharacterized protein. (818 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
FRS2Fibroblast growth factor receptor substrate 2. (522 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ENSRBIP00000040717Uncharacterized protein. (100 aa)
SHC1SHC adaptor protein 1. (584 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CSDE1-2Uncharacterized protein. (820 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (465 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
ENSRBIP00000002079Uncharacterized protein. (202 aa)
SRCTyrosine-protein kinase. (627 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
KLBKlotho beta. (947 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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