STRINGSTRING
POLD2 POLD2 POLE2 POLE2 POLK POLK ENSRBIP00000027334 ENSRBIP00000027334 RFC4 RFC4 RFC5 RFC5 ENSRBIP00000029173 ENSRBIP00000029173 RPA3 RPA3 RFC1 RFC1 PARP3 PARP3 CUL4A CUL4A GTF2H2 GTF2H2 RFC3 RFC3 LOC108529634 LOC108529634 PCNA PCNA ERCC3 ERCC3 GTF2H1 GTF2H1 UBA52 UBA52 RCBTB2 RCBTB2 GTF2H4 GTF2H4 LOC108540530 LOC108540530 ENSRBIP00000004747 ENSRBIP00000004747 LOC108521487 LOC108521487 PARP1 PARP1 POLD3 POLD3 RPS27A RPS27A ENSRBIP00000001317 ENSRBIP00000001317 ENSRBIP00000003802 ENSRBIP00000003802 ENSRBIP00000004187 ENSRBIP00000004187 ENSRBIP00000034253 ENSRBIP00000034253 CHD1L CHD1L POLE3 POLE3 GTF2H3 GTF2H3 ERCC1 ERCC1 RBX1 RBX1 PARP2 PARP2 ENSRBIP00000012514 ENSRBIP00000012514 GTF2H5 GTF2H5 ENSRBIP00000013617 ENSRBIP00000013617 ERCC4 ERCC4 ERCC2 ERCC2 ENSRBIP00000015804 ENSRBIP00000015804 POLD1 POLD1 DDB1 DDB1 ENSRBIP00000020228 ENSRBIP00000020228 RCBTB1 RCBTB1 RFC2 RFC2 POLE POLE DDB2 DDB2 POLD4 POLD4 LOC108524569 LOC108524569 POLE4 POLE4 RPA1 RPA1 XPA XPA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (492 aa)
POLKDNA polymerase kappa. (866 aa)
ENSRBIP00000027334CULLIN_2 domain-containing protein; Belongs to the cullin family. (299 aa)
RFC4Replication factor C subunit 4. (362 aa)
RFC5Replication factor C subunit 5. (309 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
RPA3Replication protein A3. (121 aa)
RFC1Replication factor C subunit 1. (1114 aa)
PARP3Poly [ADP-ribose] polymerase. (531 aa)
CUL4ACullin 4A; Belongs to the cullin family. (722 aa)
GTF2H2C2H2-type domain-containing protein. (328 aa)
RFC3Replication factor C subunit 3. (356 aa)
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
GTF2H1General transcription factor IIH subunit 1. (558 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (556 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
LOC108521487BIVM-ERCC5 readthrough. (1654 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
POLD3Uncharacterized protein. (454 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
ENSRBIP00000034253BSD domain-containing protein. (465 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (899 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (289 aa)
RBX1Ring-box 1. (108 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
ENSRBIP00000013617Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (245 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (907 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (675 aa)
ENSRBIP00000015804Cullin domain-containing protein; Belongs to the cullin family. (280 aa)
POLD1DNA polymerase. (1124 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
RFC2Replication factor C subunit 2. (352 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2253 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
POLD4Uncharacterized protein. (107 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (117 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
XPAXPA, DNA damage recognition and repair factor. (303 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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