STRINGSTRING
ENSRBIP00000001317 ENSRBIP00000001317 LOC108532799 LOC108532799 FANCM FANCM ENSRBIP00000003802 ENSRBIP00000003802 ENSRBIP00000004187 ENSRBIP00000004187 ENSRBIP00000004747 ENSRBIP00000004747 NUTF2 NUTF2 LOC108540530 LOC108540530 LOC108529634 LOC108529634 FANCA FANCA FANCD2 FANCD2 PROSER1 PROSER1 FANCG FANCG UBA52 UBA52 ENSRBIP00000008844 ENSRBIP00000008844 ENSRBIP00000010861 ENSRBIP00000010861 MEIOB MEIOB ENSRBIP00000012514 ENSRBIP00000012514 ERCC4 ERCC4 EME2 EME2 DCLRE1B DCLRE1B DCLRE1A DCLRE1A WDR48 WDR48 EME1 EME1 FAN1 FAN1 ENSRBIP00000020228 ENSRBIP00000020228 SLX1A SLX1A CENPX CENPX FANCL FANCL LOC108524569 LOC108524569 RPA1 RPA1 ATR ATR UBE2T UBE2T FAAP100 FAAP100 ENSRBIP00000029173 ENSRBIP00000029173 FANCB FANCB SLX4 SLX4 RPA3 RPA3 MUS81 MUS81 USP1 USP1 FAAP24 FAAP24 ERCC1 ERCC1 ATRIP ATRIP FANCE FANCE FANCC FANCC RPS27A RPS27A FANCI FANCI POLN POLN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
LOC108532799FANCA_interact domain-containing protein. (135 aa)
FANCMFA complementation group M. (2047 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
NUTF2NTF2 domain-containing protein. (127 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
FANCAFA complementation group A. (1375 aa)
FANCD2Uncharacterized protein. (1422 aa)
PROSER1Proline and serine rich 1. (932 aa)
FANCGFA complementation group G. (622 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
ENSRBIP00000008844NTF2 domain-containing protein. (108 aa)
ENSRBIP00000010861NTF2 domain-containing protein. (127 aa)
MEIOBMeiosis specific with OB-fold. (449 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (907 aa)
EME2Essential meiotic structure-specific endonuclease subunit 2. (377 aa)
DCLRE1BDNA cross-link repair 1B. (532 aa)
DCLRE1ADNA cross-link repair 1A. (1040 aa)
WDR48WD repeat domain 48. (644 aa)
EME1Essential meiotic structure-specific endonuclease 1. (571 aa)
FAN1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1017 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
SLX1AStructure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (275 aa)
CENPXCentromere protein X. (133 aa)
FANCLFA complementation group L. (383 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2578 aa)
UBE2TUbiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (240 aa)
FAAP100FA core complex associated protein 100. (881 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
FANCBFA complementation group B. (516 aa)
SLX4SLX4 structure-specific endonuclease subunit. (1814 aa)
RPA3Replication protein A3. (121 aa)
MUS81MUS81 structure-specific endonuclease subunit. (551 aa)
USP1Ubiquitin specific peptidase 1; Belongs to the peptidase C19 family. (773 aa)
FAAP24FA core complex associated protein 24. (215 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (289 aa)
ATRIPATR interacting protein. (790 aa)
FANCEFA complementation group E. (536 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (558 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
FANCIFA complementation group I. (1288 aa)
POLNDNA polymerase nu. (892 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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