Your Input: | |||||
AURKC | Aurora kinase C; Belongs to the protein kinase superfamily. (195 aa) | ||||
WRN | WRN RecQ like helicase. (1394 aa) | ||||
TAF7L | TATA-box binding protein associated factor 7 like. (464 aa) | ||||
RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa) | ||||
ENSRBIP00000018144 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (366 aa) | ||||
ENSRBIP00000018276 | Uncharacterized protein. (194 aa) | ||||
RECQL4 | RecQ like helicase 4. (1197 aa) | ||||
RAD50 | Zinc-hook domain-containing protein. (1281 aa) | ||||
ENSRBIP00000019958 | Uncharacterized protein. (231 aa) | ||||
SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) | ||||
ENSRBIP00000020228 | Uncharacterized protein. (132 aa) | ||||
PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3026 aa) | ||||
RFC2 | Replication factor C subunit 2. (352 aa) | ||||
ENSRBIP00000021229 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (374 aa) | ||||
MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa) | ||||
TP53RK | TP53 regulating kinase. (253 aa) | ||||
TAF6 | TATA-box binding protein associated factor 6. (737 aa) | ||||
RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (404 aa) | ||||
CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) | ||||
RAD1 | Uncharacterized protein. (280 aa) | ||||
CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) | ||||
ENSRBIP00000025123 | Protein kinase domain-containing protein. (348 aa) | ||||
LOC108524569 | Ubiquitin-like domain-containing protein. (141 aa) | ||||
CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (340 aa) | ||||
RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) | ||||
EXO1 | Exonuclease 1. (827 aa) | ||||
PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) | ||||
NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (752 aa) | ||||
TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (241 aa) | ||||
CSNK2B | Uncharacterized protein. (298 aa) | ||||
ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2578 aa) | ||||
RFC4 | Replication factor C subunit 4. (362 aa) | ||||
HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) | ||||
NOC2L | NOC2 like nucleolar associated transcriptional repressor. (762 aa) | ||||
RMI2 | RecQ mediated genome instability 2. (150 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) | ||||
RFC5 | Replication factor C subunit 5. (309 aa) | ||||
ENSRBIP00000029173 | Ubiquitin-like domain-containing protein. (166 aa) | ||||
MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa) | ||||
AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa) | ||||
TAF4 | TATA-box binding protein associated factor 4. (1026 aa) | ||||
LOC108514681 | Uncharacterized protein. (252 aa) | ||||
TAF9B | TATA-box binding protein associated factor 9b. (251 aa) | ||||
TAF1 | TATA-box binding protein associated factor 1. (1713 aa) | ||||
CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) | ||||
TAF2 | TATA-box binding protein associated factor 2. (863 aa) | ||||
HIPK2 | Homeodomain interacting protein kinase 2. (1209 aa) | ||||
RPA3 | Replication protein A3. (121 aa) | ||||
ENSRBIP00000033808 | Uncharacterized protein. (73 aa) | ||||
MAPKAPK5 | MAPK activated protein kinase 5. (471 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (364 aa) | ||||
DNA2 | DNA replication helicase/nuclease 2. (1047 aa) | ||||
PLK3 | Serine/threonine-protein kinase PLK. (647 aa) | ||||
TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (229 aa) | ||||
CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) | ||||
NUAK1 | NUAK family kinase 1. (654 aa) | ||||
CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (362 aa) | ||||
AURKA | Protein kinase domain-containing protein. (393 aa) | ||||
LOC108522544 | Protein kinase domain-containing protein. (175 aa) | ||||
LOC108518623 | TAFII28 domain-containing protein. (193 aa) | ||||
PRKAA2 | Non-specific serine/threonine protein kinase. (539 aa) | ||||
TOPBP1 | DNA topoisomerase II binding protein 1. (1527 aa) | ||||
TAF15 | TATA-box binding protein associated factor 15. (592 aa) | ||||
TAF5 | TATA-box binding protein associated factor 5. (610 aa) | ||||
RFC3 | Replication factor C subunit 3. (356 aa) | ||||
RAD17 | RAD17 checkpoint clamp loader component. (676 aa) | ||||
BARD1 | BRCA1 associated RING domain 1. (771 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1818 aa) | ||||
ATRIP | ATR interacting protein. (790 aa) | ||||
SLF1 | SMC5-SMC6 complex localization factor 1. (1050 aa) | ||||
TAF11 | TATA-box binding protein associated factor 11. (211 aa) | ||||
RBBP8 | RB binding protein 8, endonuclease. (898 aa) | ||||
ENSRBIP00000004747 | Ubiquitin-like domain-containing protein. (128 aa) | ||||
LOC108540530 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa) | ||||
LOC108529634 | Ubiquitin-like domain-containing protein. (128 aa) | ||||
BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1226 aa) | ||||
PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (371 aa) | ||||
ENSRBIP00000006659 | Protein kinase domain-containing protein. (275 aa) | ||||
PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) | ||||
STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) | ||||
RMI1 | RecQ mediated genome instability 1. (625 aa) | ||||
UBA52 | Ubiquitin-like domain-containing protein. (232 aa) | ||||
HIPK1 | Homeodomain interacting protein kinase 1. (1417 aa) | ||||
MDM2 | MDM2 proto-oncogene. (513 aa) | ||||
TPX2 | TPX2 microtubule nucleation factor. (697 aa) | ||||
TBP | TATA-box binding protein. (338 aa) | ||||
ENSRBIP00000004187 | Ubiquitin-like domain-containing protein. (153 aa) | ||||
ENSRBIP00000003802 | Ubiquitin-like domain-containing protein. (84 aa) | ||||
TAF3 | TATA-box binding protein associated factor 3. (838 aa) | ||||
ENSRBIP00000003378 | Metallophos domain-containing protein. (233 aa) | ||||
HIPK4 | Homeodomain interacting protein kinase 4. (615 aa) | ||||
NUAK2 | NUAK family kinase 2. (672 aa) | ||||
PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) | ||||
ENSRBIP00000001317 | Ubiquitin-like domain-containing protein. (155 aa) | ||||
TAF12 | TATA-box binding protein associated factor 12. (213 aa) | ||||
TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (220 aa) | ||||
RPS27A | Ubiquitin-like domain-containing protein. (156 aa) | ||||
CDCA7L | Cell division cycle associated 7 like. (455 aa) | ||||
PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa) | ||||
HIPK3 | Homeodomain interacting protein kinase 3. (1215 aa) | ||||
HUS1B | Checkpoint protein; Belongs to the HUS1 family. (277 aa) | ||||
PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) | ||||
TAF4B | TATA-box binding protein associated factor 4b. (862 aa) | ||||
BLM | BLM RecQ like helicase. (1396 aa) | ||||
CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) | ||||
ENSRBIP00000012047 | Peptidyl-prolyl cis-trans isomerase. (154 aa) | ||||
DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (588 aa) | ||||
CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa) | ||||
MEIOB | Meiosis specific with OB-fold. (449 aa) | ||||
ENSRBIP00000012514 | Ubiquitin-like domain-containing protein. (121 aa) | ||||
RHNO1 | Uncharacterized protein. (240 aa) | ||||
ENSRBIP00000013688 | Uncharacterized protein. (232 aa) | ||||
TBPL1 | TATA-box binding protein like 1. (186 aa) | ||||
EXD2 | Exonuclease 3'-5' domain containing 2. (621 aa) | ||||
TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa) | ||||
TDRD3 | Tudor domain containing 3. (749 aa) | ||||
CHEK2 | Checkpoint kinase 2. (589 aa) | ||||
DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (595 aa) | ||||
DYRK4 | Dual specificity tyrosine phosphorylation regulated kinase 4. (636 aa) | ||||
ENSRBIP00000015197 | Uncharacterized protein. (114 aa) |