STRINGSTRING
GRB2 GRB2 TNS4 TNS4 LAMA1 LAMA1 STAM2 STAM2 GGA3 GGA3 SH3GL3 SH3GL3 COL5A1 COL5A1 LAMA4 LAMA4 LAMC3 LAMC3 ENSRBIP00000012514 ENSRBIP00000012514 STAM STAM FNDC3B FNDC3B PTK2 PTK2 ENSRBIP00000009767 ENSRBIP00000009767 ENSRBIP00000009622 ENSRBIP00000009622 COL3A1 COL3A1 ENSRBIP00000026419 ENSRBIP00000026419 DOCK7 DOCK7 LOC108524569 LOC108524569 RAPGEF1 RAPGEF1 LAMA3 LAMA3 ITGA3 ITGA3 RPS27A RPS27A FN1 FN1 CRK CRK ENSRBIP00000001317 ENSRBIP00000001317 PIK3R1 PIK3R1 COL2A1 COL2A1 ARF6 ARF6 ENSRBIP00000002079 ENSRBIP00000002079 SRC SRC PTPN1 PTPN1 COL1A2 COL1A2 HPN HPN RAP1A RAP1A ENSRBIP00000003802 ENSRBIP00000003802 ENSRBIP00000004187 ENSRBIP00000004187 LAMA5 LAMA5 ENSRBIP00000004747 ENSRBIP00000004747 LOC108540530 LOC108540530 LOC108529634 LOC108529634 HGS HGS RAP1B RAP1B COL27A1 COL27A1 HGFAC HGFAC ERAS ERAS LAMB1 LAMB1 RANBP9 RANBP9 ENSRBIP00000007280 ENSRBIP00000007280 SH3GL2 SH3GL2 LAMA2 LAMA2 TNS3 TNS3 UBA52 UBA52 STAT3 STAT3 RAB4B RAB4B COL11A2 COL11A2 LAMB2 LAMB2 ENSRBIP00000022156 ENSRBIP00000022156 SH3GL1 SH3GL1 HRAS HRAS LAMC2 LAMC2 ITGB1 ITGB1 COL11A1 COL11A1 ENSRBIP00000020228 ENSRBIP00000020228 TNS1 TNS1 EPS15 EPS15 COL5A3 COL5A3 COL5A2 COL5A2 SPINT2 SPINT2 SHC1 SHC1 ENSRBIP00000040717 ENSRBIP00000040717 HGF HGF NRAS NRAS RAB4A RAB4A LRIG1 LRIG1 FNDC3A FNDC3A CBL CBL RANBP10 RANBP10 ITGA2 ITGA2 MET MET SOS1 SOS1 COL24A1 COL24A1 SPINT1 SPINT1 MUC20 MUC20 ENSRBIP00000032719 ENSRBIP00000032719 COL1A1 COL1A1 GAB1 GAB1 PTPN2 PTPN2 USP8 USP8 LAMC1 LAMC1 CSDE1 CSDE1 LAMB3 LAMB3 CRKL CRKL ENSRBIP00000029173 ENSRBIP00000029173 PTPRJ PTPRJ CSDE1-2 CSDE1-2 PTPN11 PTPN11 ENSRBIP00000026744 ENSRBIP00000026744 KRAS KRAS SH3KBP1 SH3KBP1 PIK3CA PIK3CA ENSRBIP00000016878 ENSRBIP00000016878 MEGF11 MEGF11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRB2Growth factor receptor bound protein 2. (217 aa)
TNS4Tensin 4. (715 aa)
LAMA1Laminin subunit alpha 1. (3080 aa)
STAM2Signal transducing adaptor molecule 2. (519 aa)
GGA3Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (723 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (286 aa)
COL5A1Collagen type V alpha 1 chain. (1731 aa)
LAMA4Laminin subunit alpha 4. (1816 aa)
LAMC3Laminin subunit gamma 3. (1535 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
STAMSignal transducing adaptor molecule. (540 aa)
FNDC3BFibronectin type III domain containing 3B. (1178 aa)
PTK2Protein tyrosine kinase 2. (1078 aa)
ENSRBIP00000009767Uncharacterized protein. (546 aa)
ENSRBIP00000009622Uncharacterized protein. (329 aa)
COL3A1Collagen type III alpha 1 chain. (1333 aa)
ENSRBIP00000026419Uncharacterized protein. (249 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2049 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1095 aa)
LAMA3Laminin subunit alpha 3. (3324 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1087 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
FN1Fibronectin 1. (2477 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ENSRBIP00000002079Uncharacterized protein. (202 aa)
SRCTyrosine-protein kinase. (627 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
HPNHepsin; Belongs to the peptidase S1 family. (460 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
LAMA5Laminin subunit alpha 5. (3606 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
RAP1BUncharacterized protein. (184 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1860 aa)
HGFACHGF activator; Belongs to the peptidase S1 family. (647 aa)
ERASES cell expressed Ras. (233 aa)
LAMB1Laminin subunit beta 1. (1768 aa)
RANBP9RAN binding protein 9. (625 aa)
ENSRBIP00000007280Tyrosine-protein phosphatase non-receptor type. (354 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (315 aa)
LAMA2Laminin subunit alpha 2. (3094 aa)
TNS3Tensin 3. (1445 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
RAB4BUncharacterized protein. (221 aa)
COL11A2Collagen type XI alpha 2 chain. (1738 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
ENSRBIP00000022156Uncharacterized protein. (152 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (937 aa)
COL11A1Collagen type XI alpha 1 chain. (1745 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
TNS1Tensin 1. (1728 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (899 aa)
COL5A3Collagen type V alpha 3 chain. (1680 aa)
COL5A2Collagen type V alpha 2 chain. (1424 aa)
SPINT2Serine peptidase inhibitor, Kunitz type 2. (252 aa)
SHC1SHC adaptor protein 1. (584 aa)
ENSRBIP00000040717Uncharacterized protein. (100 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
RAB4ARAB4A, member RAS oncogene family. (220 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1090 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
CBLCbl proto-oncogene. (802 aa)
RANBP10RAN binding protein 10. (647 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1383 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1293 aa)
COL24A1Collagen type XXIV alpha 1 chain. (1630 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (530 aa)
MUC20Mucin 20, cell surface associated. (503 aa)
ENSRBIP00000032719SH2 domain-containing protein. (203 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
GAB1GRB2 associated binding protein 1. (722 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (387 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1105 aa)
LAMC1Laminin subunit gamma 1. (1587 aa)
CSDE1Uncharacterized protein. (818 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1336 aa)
CSDE1-2Uncharacterized protein. (820 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
ENSRBIP00000026744Uncharacterized protein. (153 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (372 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
ENSRBIP00000016878Uncharacterized protein. (251 aa)
MEGF11Multiple EGF like domains 11. (1140 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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