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| | LOC108541777 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | ENSRBIP00000000223 | Proteasome endopeptidase complex. (207 aa) |
| | PSME3 | Proteasome activator subunit 3. (265 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | RBBP4 | WD_REPEATS_REGION domain-containing protein. (419 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | ENSRBIP00000001251 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (167 aa) |
| | ENSRBIP00000001317 | Ubiquitin-like domain-containing protein. (155 aa) |
| | ENSRBIP00000001324 | Uncharacterized protein. (91 aa) |
| | ENSRBIP00000001425 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (158 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | ENSRBIP00000001447 | ANK_REP_REGION domain-containing protein. (152 aa) |
| | STAG1 | Stromal antigen 1. (1219 aa) |
| | GINS1 | GINS complex subunit 1. (196 aa) |
| | PSMA8 | Proteasome subunit alpha type. (256 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | ESCO2 | Establishment of sister chromatid cohesion N-acetyltransferase 2. (601 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1127 aa) |
| | E2F5 | E2F transcription factor 5. (345 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | ENSRBIP00000003285 | Uncharacterized protein. (215 aa) |
| | MCM8 | MCM domain-containing protein; Belongs to the MCM family. (880 aa) |
| | LOC108544295 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) |
| | ENSRBIP00000003802 | Ubiquitin-like domain-containing protein. (84 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1233 aa) |
| | ENSRBIP00000004187 | Ubiquitin-like domain-containing protein. (153 aa) |
| | ENSRBIP00000004747 | Ubiquitin-like domain-containing protein. (128 aa) |
| | ENSRBIP00000005036 | Cyclin N-terminal domain-containing protein. (74 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) |
| | LOC108540530 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa) |
| | LOC108529634 | Ubiquitin-like domain-containing protein. (128 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | ENSRBIP00000006126 | ANK_REP_REGION domain-containing protein. (152 aa) |
| | LOC108523335 | Ubiquitin-conjugating enzyme E2 C. (179 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (570 aa) |
| | CDC16 | Cell division cycle 16. (620 aa) |
| | TFDP2 | Transcription factor. (429 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1140 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | CDCA5 | Cell division cycle associated 5. (288 aa) |
| | UBA52 | Ubiquitin-like domain-containing protein. (232 aa) |
| | RCBTB2 | RCC1 and BTB domain containing protein 2. (556 aa) |
| | TM4SF19 | Uncharacterized protein. (295 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (140 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | ENSRBIP00000008912 | CAF1C_H4-bd domain-containing protein. (55 aa) |
| | ENSRBIP00000009490 | Uncharacterized protein. (81 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1718 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (184 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | AKT1 | AKT serine/threonine kinase 1. (486 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (939 aa) |
| | LOC108525766 | Uncharacterized protein. (80 aa) |
| | ORC3 | ORC_WH_C domain-containing protein. (316 aa) |
| | PTK6 | Tyrosine-protein kinase. (451 aa) |
| | ENSRBIP00000012328 | CSN8_PSD8_EIF3K domain-containing protein. (235 aa) |
| | MEIOB | Meiosis specific with OB-fold. (449 aa) |
| | ENSRBIP00000012514 | Ubiquitin-like domain-containing protein. (121 aa) |
| | PSMA7 | Proteasome subunit alpha type. (247 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa) |
| | ENSRBIP00000012931 | CAF1C_H4-bd domain-containing protein. (100 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | PDS5A | PDS5 cohesin associated factor A. (1300 aa) |
| | GMNN | Geminin DNA replication inhibitor. (209 aa) |
| | ENSRBIP00000013617 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (245 aa) |
| | LOC108515681 | Proteasome subunit beta. (263 aa) |
| | WEE2 | Wee1-like protein kinase. (567 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (380 aa) |
| | ENSRBIP00000015001 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (166 aa) |
| | ENSRBIP00000015150 | Proteasome subunit alpha type. (239 aa) |
| | ANAPC11 | Anaphase promoting complex subunit 11. (180 aa) |
| | ENSRBIP00000015325 | Proteasome endopeptidase complex. (228 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | ENSRBIP00000015539 | Proteasome subunit beta. (241 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (451 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (510 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | POLD1 | DNA polymerase. (1124 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | PSMD10 | ANK_REP_REGION domain-containing protein. (226 aa) |
| | ENSRBIP00000017801 | Uncharacterized protein. (86 aa) |
| | PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa) |
| | E2F1 | E2F transcription factor 1. (423 aa) |
| | ORC2 | Origin recognition complex subunit 2. (575 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (269 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | ENSRBIP00000018676 | JAB_MPN domain-containing protein. (262 aa) |
| | ENSRBIP00000019159 | MPN domain-containing protein. (300 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (480 aa) |
| | ANAPC15 | Anaphase promoting complex subunit 15. (190 aa) |
| | RB1 | RB transcriptional corepressor 1. (815 aa) |
| | ENSRBIP00000020047 | Uncharacterized protein; Belongs to the SKP1 family. (162 aa) |
| | ENSRBIP00000020228 | Uncharacterized protein. (132 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | ENSRBIP00000020382 | ANK_REP_REGION domain-containing protein. (102 aa) |
| | UBE2E1 | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (907 aa) |
| | CDC25B | Cell division cycle 25B. (580 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | ENSRBIP00000021940 | AAA domain-containing protein. (190 aa) |
| | FAM89A | Family with sequence similarity 89 member A. (175 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2253 aa) |
| | ENSRBIP00000022388 | AAA domain-containing protein. (353 aa) |
| | LOC108522364 | Uncharacterized protein. (389 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | ENSRBIP00000022765 | Uncharacterized protein. (185 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | ENSRBIP00000022922 | Protein kinase domain-containing protein. (254 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | ENSRBIP00000023172 | Uncharacterized protein. (1181 aa) |
| | PSMB5 | Uncharacterized protein. (262 aa) |
| | CDC23 | Cell division cycle 23. (597 aa) |
| | WAPL | WAPL cohesin release factor. (1189 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (309 aa) |
| | ENSRBIP00000024800 | DOC domain-containing protein. (124 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (828 aa) |
| | POLD4 | Uncharacterized protein. (107 aa) |
| | LOC108524569 | Ubiquitin-like domain-containing protein. (141 aa) |
| | ENSRBIP00000025332 | Uncharacterized protein. (368 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (117 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | PSMA3 | Proteasome subunit alpha type. (256 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | CCND1 | Cyclin D1. (156 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (246 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (504 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (492 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (755 aa) |
| | RFC4 | Replication factor C subunit 4. (362 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | ORC5 | Origin recognition complex subunit 5. (424 aa) |
| | CDC27 | Cell division cycle 27. (803 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa) |
| | PSMB11 | Proteasome subunit beta 11. (245 aa) |
| | TCERG1L | Transcription elongation regulator 1 like. (542 aa) |
| | CDC45 | Cell division cycle 45. (552 aa) |
| | RFC5 | Replication factor C subunit 5. (309 aa) |
| | ESCO1 | Establishment of sister chromatid cohesion N-acetyltransferase 1. (827 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (325 aa) |
| | ENSRBIP00000029173 | Ubiquitin-like domain-containing protein. (166 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (435 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (556 aa) |
| | ENSRBIP00000030654 | Uncharacterized protein. (209 aa) |
| | UBE2C | Ubiquitin conjugating enzyme E2 C. (179 aa) |
| | RAD21 | RAD21 cohesin complex component. (584 aa) |
| | ENSRBIP00000030799 | Uncharacterized protein. (372 aa) |
| | SKP2 | S-phase kinase associated protein 2. (424 aa) |
| | ENSRBIP00000031680 | WD_REPEATS_REGION domain-containing protein. (408 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa) |
| | GINS3 | GINS complex subunit 3. (255 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | CDC25A | Cell division cycle 25A. (486 aa) |
| | ANAPC16 | Anaphase promoting complex subunit 16. (110 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (116 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (486 aa) |
| | ENSRBIP00000032894 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (77 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | ENSRBIP00000033359 | AAA domain-containing protein. (401 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | ENSRBIP00000033421 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (124 aa) |
| | RFC1 | Replication factor C subunit 1. (1114 aa) |
| | KIAA2012 | KIAA2012. (1180 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (496 aa) |
| | E2F4 | E2F transcription factor 4. (415 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (403 aa) |
| | AKT3 | AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa) |
| | PSME4 | Proteasome activator subunit 4. (1844 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1047 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (421 aa) |
| | ENSRBIP00000035529 | WD_REPEATS_REGION domain-containing protein. (235 aa) |
| | ENSRBIP00000036162 | WD_REPEATS_REGION domain-containing protein. (399 aa) |
| | SKP1 | Uncharacterized protein; Belongs to the SKP1 family. (154 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (362 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (529 aa) |
| | WEE1 | Wee1-like protein kinase. (588 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | ENSRBIP00000038433 | AAA domain-containing protein; Belongs to the AAA ATPase family. (425 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (319 aa) |
| | PSMB6 | Uncharacterized protein. (227 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | FAM89B | Family with sequence similarity 89 member B. (189 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | ENSRBIP00000039839 | Uncharacterized protein; Belongs to the SKP1 family. (129 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | ENSRBIP00000040220 | Uncharacterized protein. (112 aa) |
| | MAX | MYC associated factor X. (162 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (360 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | LIG1 | DNA ligase. (928 aa) |
| | ENSRBIP00000040579 | Sld5 domain-containing protein. (151 aa) |
| | RBX1 | Ring-box 1. (108 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (807 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1208 aa) |
| | PDS5B | PDS5 cohesin associated factor B. (1430 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1944 aa) |
| | POLD3 | Uncharacterized protein. (454 aa) |
| | LOC108532656 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (172 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (498 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (512 aa) |
