40 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HBEGF	Heparin binding EGF like growth factor. (208 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	MATK	Tyrosine-protein kinase. (554 aa)
	ENSRBIP00000001317	Ubiquitin-like domain-containing protein. (155 aa)
	ENSRBIP00000003802	Ubiquitin-like domain-containing protein. (84 aa)
	ENSRBIP00000004187	Ubiquitin-like domain-containing protein. (153 aa)
	ENSRBIP00000004747	Ubiquitin-like domain-containing protein. (128 aa)
	NRG4	Neuregulin 4. (88 aa)
	LOC108540530	Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
	LOC108529634	Ubiquitin-like domain-containing protein. (128 aa)
	EREG	Epiregulin. (169 aa)
	UBA52	Ubiquitin-like domain-containing protein. (232 aa)
	AKT1	AKT serine/threonine kinase 1. (486 aa)
	STUB1	STIP1 homology and U-box containing protein 1. (303 aa)
	ENSRBIP00000012180	Uncharacterized protein. (348 aa)
	ENSRBIP00000012514	Ubiquitin-like domain-containing protein. (121 aa)
	CUL5	Cullin 5; Belongs to the cullin family. (774 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
	PTPN12	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (763 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1308 aa)
	ENSRBIP00000020228	Uncharacterized protein. (132 aa)
	LOC108537061	HATPase_c domain-containing protein. (384 aa)
	ENSRBIP00000022670	Uncharacterized protein. (281 aa)
	LOC108524569	Ubiquitin-like domain-containing protein. (141 aa)
	NRG2	Neuregulin 2. (729 aa)
	BTC	Betacellulin. (129 aa)
	CDC37	Cell division cycle 37. (378 aa)
	ERBB3	Erb-b2 receptor tyrosine kinase 3. (1291 aa)
	ENSRBIP00000029173	Ubiquitin-like domain-containing protein. (166 aa)
	RNF41	Ring finger protein 41. (317 aa)
	NRG1	Neuregulin 1. (713 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1105 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	HSP90AA1	Heat shock protein 90 alpha family class A member 1. (686 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	ENSRBIP00000034107	HATPase_c domain-containing protein. (638 aa)
	AKT3	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
	EGFR	Receptor protein-tyrosine kinase. (1210 aa)
	NRG3	Neuregulin 3. (402 aa)
	ERBIN	Erbb2 interacting protein. (1418 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSRBIP00000010710	ENSRBIP00000034007	AKT serine/threonine kinase 1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.708
AKT1	CDC37	ENSRBIP00000010710	ENSRBIP00000027498	AKT serine/threonine kinase 1.	Cell division cycle 37.	0.704
AKT1	EGF	ENSRBIP00000010710	ENSRBIP00000016377	AKT serine/threonine kinase 1.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.601
AKT1	EGFR	ENSRBIP00000010710	ENSRBIP00000037373	AKT serine/threonine kinase 1.	Receptor protein-tyrosine kinase.	0.417
AKT1	ENSRBIP00000012180	ENSRBIP00000010710	ENSRBIP00000012180	AKT serine/threonine kinase 1.	Uncharacterized protein.	0.588
AKT1	ENSRBIP00000022670	ENSRBIP00000010710	ENSRBIP00000022670	AKT serine/threonine kinase 1.	Uncharacterized protein.	0.762
AKT1	ENSRBIP00000034107	ENSRBIP00000010710	ENSRBIP00000034107	AKT serine/threonine kinase 1.	HATPase_c domain-containing protein.	0.762
AKT1	ERBB3	ENSRBIP00000010710	ENSRBIP00000027949	AKT serine/threonine kinase 1.	Erb-b2 receptor tyrosine kinase 3.	0.505
AKT1	HSP90AA1	ENSRBIP00000010710	ENSRBIP00000033238	AKT serine/threonine kinase 1.	Heat shock protein 90 alpha family class A member 1.	0.762
AKT1	LOC108537061	ENSRBIP00000010710	ENSRBIP00000020527	AKT serine/threonine kinase 1.	HATPase_c domain-containing protein.	0.762
AKT1	STUB1	ENSRBIP00000010710	ENSRBIP00000011071	AKT serine/threonine kinase 1.	STIP1 homology and U-box containing protein 1.	0.498
AKT1	USP8	ENSRBIP00000010710	ENSRBIP00000030657	AKT serine/threonine kinase 1.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.590
AKT2	AKT1	ENSRBIP00000034007	ENSRBIP00000010710	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	AKT serine/threonine kinase 1.	0.708
AKT2	AKT3	ENSRBIP00000034007	ENSRBIP00000034274	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily.	0.939
AKT2	CDC37	ENSRBIP00000034007	ENSRBIP00000027498	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cell division cycle 37.	0.933
AKT2	EGFR	ENSRBIP00000034007	ENSRBIP00000037373	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.407
AKT2	ENSRBIP00000022670	ENSRBIP00000034007	ENSRBIP00000022670	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.485
AKT2	ENSRBIP00000034107	ENSRBIP00000034007	ENSRBIP00000034107	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	HATPase_c domain-containing protein.	0.485
AKT2	HSP90AA1	ENSRBIP00000034007	ENSRBIP00000033238	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock protein 90 alpha family class A member 1.	0.485
AKT2	LOC108537061	ENSRBIP00000034007	ENSRBIP00000020527	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	HATPase_c domain-containing protein.	0.946