59 items (Rhinopithecus bieti) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	LOC108527145	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
	ENSRBIP00000015709	Uncharacterized protein. (205 aa)
	LOC108532627	Hist_deacetyl domain-containing protein. (210 aa)
	MOBP	Myelin associated oligodendrocyte basic protein. (196 aa)
	CAMK4	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (472 aa)
	TNRC6B	Trinucleotide repeat containing adaptor 6B. (1832 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	IRAK1	Interleukin 1 receptor associated kinase 1. (702 aa)
	PTPN4	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa)
	HTT	Huntingtin. (3068 aa)
	NCOR2	Nuclear receptor corepressor 2. (2488 aa)
	ENSRBIP00000029999	Protein kinase domain-containing protein. (335 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
	GRIA2	Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
	TRPC3	Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
	AGO4	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (848 aa)
	HIPK2	Homeodomain interacting protein kinase 2. (1209 aa)
	AGO2	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (879 aa)
	ENSRBIP00000008820	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (470 aa)
	TBL1X	Transducin beta like 1 X-linked. (586 aa)
	CAMK2D	Protein kinase domain-containing protein. (533 aa)
	BDNF	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (312 aa)
	TNRC6C	Trinucleotide repeat containing adaptor 6C. (1935 aa)
	TBL1XR1	Transducin beta like 1 X-linked receptor 1. (514 aa)
	FOXG1	Forkhead box G1. (445 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (748 aa)
	GPS2	G protein pathway suppressor 2. (327 aa)
	FKBP5	Peptidylprolyl isomerase. (457 aa)
	DGCR8	DGCR8 microprocessor complex subunit. (773 aa)
	TNRC6A	Trinucleotide repeat containing adaptor 6A. (1951 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (435 aa)
	CRH	Corticotropin releasing hormone. (196 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	SGK1	Non-specific serine/threonine protein kinase. (526 aa)
	AGO1	Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
	MET	MET proto-oncogene, receptor tyrosine kinase. (1383 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	MOV10	Mov10 RISC complex RNA helicase. (1003 aa)
	CAMK2A	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
	SIN3A	SIN3 transcription regulator family member A. (1228 aa)
	PTEN	Uncharacterized protein. (555 aa)
	NCOR1	Nuclear receptor corepressor 1. (2441 aa)
	PVALB	Parvalbumin; Belongs to the parvalbumin family. (110 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (298 aa)
	GAD1	Glutamate decarboxylase 1. (594 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma. (547 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
	LBR	Lamin B receptor. (609 aa)
	AGO3	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
	GAD2	Glutamate decarboxylase 2. (585 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
	RBFOX1	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events. (414 aa)
	SST	Somatostatin. (116 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	GAMT	Guanidinoacetate N-methyltransferase. (251 aa)
	ENSRBIP00000018271	Hist_deacetyl domain-containing protein. (180 aa)
	PPARG-2	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (217 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO1	AGO2	ENSRBIP00000017207	ENSRBIP00000009252	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.976
AGO1	AGO3	ENSRBIP00000017207	ENSRBIP00000040746	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	0.745
AGO1	AGO4	ENSRBIP00000017207	ENSRBIP00000032803	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	0.794
AGO1	DGCR8	ENSRBIP00000017207	ENSRBIP00000003216	Argonaute RISC component 1; Belongs to the argonaute family.	DGCR8 microprocessor complex subunit.	0.675
AGO1	ENSRBIP00000015709	ENSRBIP00000017207	ENSRBIP00000015709	Argonaute RISC component 1; Belongs to the argonaute family.	Uncharacterized protein.	0.624
AGO1	MOV10	ENSRBIP00000017207	ENSRBIP00000034177	Argonaute RISC component 1; Belongs to the argonaute family.	Mov10 RISC complex RNA helicase.	0.711
AGO1	TNRC6A	ENSRBIP00000017207	ENSRBIP00000003046	Argonaute RISC component 1; Belongs to the argonaute family.	Trinucleotide repeat containing adaptor 6A.	0.985
AGO1	TNRC6B	ENSRBIP00000017207	ENSRBIP00000023375	Argonaute RISC component 1; Belongs to the argonaute family.	Trinucleotide repeat containing adaptor 6B.	0.878
AGO1	TNRC6C	ENSRBIP00000017207	ENSRBIP00000007799	Argonaute RISC component 1; Belongs to the argonaute family.	Trinucleotide repeat containing adaptor 6C.	0.868
AGO2	AGO1	ENSRBIP00000009252	ENSRBIP00000017207	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Argonaute RISC component 1; Belongs to the argonaute family.	0.976
AGO2	AGO3	ENSRBIP00000009252	ENSRBIP00000040746	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	0.904
AGO2	AGO4	ENSRBIP00000009252	ENSRBIP00000032803	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	0.906
AGO2	DGCR8	ENSRBIP00000009252	ENSRBIP00000003216	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	DGCR8 microprocessor complex subunit.	0.730
AGO2	ENSRBIP00000015709	ENSRBIP00000009252	ENSRBIP00000015709	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Uncharacterized protein.	0.859
AGO2	HTT	ENSRBIP00000009252	ENSRBIP00000029230	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Huntingtin.	0.608
AGO2	IRAK1	ENSRBIP00000009252	ENSRBIP00000026395	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Interleukin 1 receptor associated kinase 1.	0.497
AGO2	MOV10	ENSRBIP00000009252	ENSRBIP00000034177	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Mov10 RISC complex RNA helicase.	0.798
AGO2	TNRC6A	ENSRBIP00000009252	ENSRBIP00000003046	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Trinucleotide repeat containing adaptor 6A.	0.990
AGO2	TNRC6B	ENSRBIP00000009252	ENSRBIP00000023375	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Trinucleotide repeat containing adaptor 6B.	0.939
AGO2	TNRC6C	ENSRBIP00000009252	ENSRBIP00000007799	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Trinucleotide repeat containing adaptor 6C.	0.938