STRINGSTRING
CSDE1-2 CSDE1-2 UHMK1 UHMK1 ENSRBIP00000042195 ENSRBIP00000042195 IGF1R IGF1R SHC1 SHC1 GNAI3 GNAI3 ENSRBIP00000040717 ENSRBIP00000040717 GNG10 GNG10 NRAS NRAS GNGT2 GNGT2 EGFR EGFR PRKCZ PRKCZ AREG AREG GNB5 GNB5 FOXO3 FOXO3 AKT3 AKT3 ENSRBIP00000034184 ENSRBIP00000034184 NOS3 NOS3 ENSRBIP00000034107 ENSRBIP00000034107 ZDHHC21 ZDHHC21 AKT2 AKT2 CREB1 CREB1 HSP90AA1 HSP90AA1 GNG8 GNG8 GNB1 GNB1 PRMT8 PRMT8 GNG12 GNG12 CSDE1 CSDE1 GNAI2 GNAI2 HBEGF HBEGF ZDHHC7 ZDHHC7 BTC BTC PRMT1 PRMT1 ESR2 ESR2 CAV2 CAV2 KRAS KRAS MAPK1 MAPK1 GNG3 GNG3 CCND1 CCND1 SPHK1 SPHK1 FOS FOS MMP7 MMP7 STRN STRN ENSRBIP00000022670 ENSRBIP00000022670 GNG2 GNG2 HRAS HRAS MMP2 MMP2 LOC108537061 LOC108537061 STRN3 STRN3 GNG11 GNG11 GNG5 GNG5 GNG4 GNG4 PIK3CA PIK3CA GNB3 GNB3 GNB2 GNB2 EGF EGF CAV1 CAV1 ENSRBIP00000015185 ENSRBIP00000015185 PDPK1 PDPK1 GNAI1 GNAI1 TGFA TGFA PIK3R2 PIK3R2 STRN4 STRN4 ENSRBIP00000013453 ENSRBIP00000013453 EPGN EPGN ENSRBIP00000013012 ENSRBIP00000013012 HSPB1 HSPB1 ENSRBIP00000011770 ENSRBIP00000011770 GNAT3 GNAT3 XPO1 XPO1 BCL2 BCL2 AKT1 AKT1 GNG13 GNG13 PTK2 PTK2 GNG7 GNG7 EREG EREG ENSRBIP00000007423 ENSRBIP00000007423 ENSRBIP00000007140 ENSRBIP00000007140 GNB4 GNB4 ELK1 ELK1 ERAS ERAS ENSRBIP00000005036 ENSRBIP00000005036 MMP9 MMP9 MMP3 MMP3 S1PR3 S1PR3 PIK3R3 PIK3R3 SRC SRC ESR1 ESR1 PIK3R1 PIK3R1 WDR64 WDR64 CDKN1B CDKN1B MAPK3 MAPK3 ENSRBIP00000000203 ENSRBIP00000000203 SRF SRF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSDE1-2Uncharacterized protein. (820 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
ENSRBIP00000042195Uncharacterized protein. (122 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
SHC1SHC adaptor protein 1. (584 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ENSRBIP00000040717Uncharacterized protein. (100 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (62 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
AREGAmphiregulin. (264 aa)
GNB5G protein subunit beta 5. (403 aa)
FOXO3Forkhead box O3. (672 aa)
AKT3AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
ENSRBIP00000034184G protein gamma domain-containing protein. (68 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
ENSRBIP00000034107HATPase_c domain-containing protein. (638 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (686 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNB1G protein subunit beta 1. (340 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
CSDE1Uncharacterized protein. (818 aa)
GNAI2G protein subunit alpha i2. (355 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (336 aa)
BTCBetacellulin. (129 aa)
PRMT1Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
ESR2Estrogen receptor 2. (530 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CCND1Cyclin D1. (156 aa)
SPHK1Sphingosine kinase 1. (384 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MMP7Matrix metallopeptidase 7. (270 aa)
STRNStriatin. (751 aa)
ENSRBIP00000022670Uncharacterized protein. (281 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (102 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
LOC108537061HATPase_c domain-containing protein. (384 aa)
STRN3Striatin 3. (797 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
GNB3G protein subunit beta 3. (340 aa)
GNB2G protein subunit beta 2. (368 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
ENSRBIP00000015185ETS domain-containing protein. (421 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (351 aa)
GNAI1G protein subunit alpha i1. (331 aa)
TGFATransforming growth factor alpha. (166 aa)
PIK3R2Uncharacterized protein. (626 aa)
STRN4Striatin 4. (672 aa)
ENSRBIP00000013453SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (173 aa)
EPGNEpithelial mitogen. (156 aa)
ENSRBIP00000013012Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
ENSRBIP00000011770Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
XPO1Exportin 1. (1030 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
AKT1AKT serine/threonine kinase 1. (486 aa)
GNG13G protein subunit gamma 13. (67 aa)
PTK2Protein tyrosine kinase 2. (1078 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
EREGEpiregulin. (169 aa)
ENSRBIP00000007423Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ENSRBIP00000007140Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (307 aa)
GNB4G protein subunit beta 4. (340 aa)
ELK1ETS domain-containing protein. (428 aa)
ERASES cell expressed Ras. (233 aa)
ENSRBIP00000005036Cyclin N-terminal domain-containing protein. (74 aa)
MMP9Matrix metallopeptidase 9. (703 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
SRCTyrosine-protein kinase. (627 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
WDR64WD repeat domain 64. (1068 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
ENSRBIP00000000203Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (250 aa)
SRFSerum response factor. (508 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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