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VAV2 VAV2 LOC108530360 LOC108530360 ELMO1 ELMO1 SRC SRC HCK HCK ARPC4 ARPC4 ACTB ACTB ARPC1B ARPC1B BRK1 BRK1 ABI1 ABI1 ACTRT1 ACTRT1 ENSRBIP00000005991 ENSRBIP00000005991 FYN FYN MYO5A MYO5A CD3G CD3G ABL1 ABL1 ARPC5 ARPC5 PTK2 PTK2 CYFIP1 CYFIP1 ACTL7B ACTL7B ARPC3 ARPC3 NCK1 NCK1 LOC108520315 LOC108520315 ENSRBIP00000000419 ENSRBIP00000000419 MAPK3 MAPK3 CD247 CD247 CRK CRK NCKIPSD NCKIPSD WIPF2 WIPF2 ENSRBIP00000015347 ENSRBIP00000015347 ENSRBIP00000016224 ENSRBIP00000016224 GRB2 GRB2 ENSRBIP00000016723 ENSRBIP00000016723 WASL WASL NCKAP1L NCKAP1L WASF3 WASF3 ENSRBIP00000019284 ENSRBIP00000019284 WIPF3 WIPF3 ACTR3 ACTR3 ENSRBIP00000021960 ENSRBIP00000021960 MYO9B MYO9B ENSRBIP00000022666 ENSRBIP00000022666 SYK SYK ARPC2 ARPC2 BAIAP2 BAIAP2 ENSRBIP00000024420 ENSRBIP00000024420 ENSRBIP00000024768 ENSRBIP00000024768 MAPK1 MAPK1 ENSRBIP00000026615 ENSRBIP00000026615 ACTL7A ACTL7A ENSRBIP00000027876 ENSRBIP00000027876 ENSRBIP00000028717 ENSRBIP00000028717 ENSRBIP00000029649 ENSRBIP00000029649 ENSRBIP00000031488 ENSRBIP00000031488 FGR FGR MYO10 MYO10 YES1 YES1 ACTG1 ACTG1 MYO1C MYO1C ACTR2 ACTR2 LOC108516810 LOC108516810 WASF1 WASF1 VAV1 VAV1 NCKAP1 NCKAP1 WIPF1 WIPF1 ENSRBIP00000035213 ENSRBIP00000035213 LYN LYN VAV3 VAV3 ENSRBIP00000036977 ENSRBIP00000036977 WASF2 WASF2 ELMO2 ELMO2 CDC42 CDC42 CYFIP2 CYFIP2 ENSRBIP00000037737 ENSRBIP00000037737 MYH9 MYH9 DOCK1 DOCK1 BTK BTK WAS WAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VAV2Vav guanine nucleotide exchange factor 2. (783 aa)
LOC108530360Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
ELMO1Engulfment and cell motility 1. (692 aa)
SRCTyrosine-protein kinase. (627 aa)
HCKTyrosine-protein kinase. (517 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (189 aa)
ACTBActin beta. (379 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (375 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
ABI1Abl interactor 1. (508 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
ENSRBIP00000005991Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (170 aa)
FYNTyrosine-protein kinase. (537 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1765 aa)
CD3GCD3g molecule. (181 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
PTK2Protein tyrosine kinase 2. (1078 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
ACTL7BActin like 7B; Belongs to the actin family. (399 aa)
ARPC3Uncharacterized protein. (134 aa)
NCK1NCK adaptor protein 1. (371 aa)
LOC108520315Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1900 aa)
ENSRBIP00000000419Uncharacterized protein. (191 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
CD247CD247 molecule. (165 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
NCKIPSDNCK interacting protein with SH3 domain. (722 aa)
WIPF2WAS/WASL interacting protein family member 2. (439 aa)
ENSRBIP00000015347Uncharacterized protein. (182 aa)
ENSRBIP00000016224Uncharacterized protein. (184 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSRBIP00000016723Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (164 aa)
WASLWASP like actin nucleation promoting factor. (504 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
WASF3WASP family member 3. (502 aa)
ENSRBIP00000019284Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (169 aa)
WIPF3WAS/WASL interacting protein family member 3. (423 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (368 aa)
ENSRBIP00000021960Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (137 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2161 aa)
ENSRBIP00000022666Uncharacterized protein. (379 aa)
SYKUncharacterized protein. (331 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
BAIAP2BAI1 associated protein 2. (605 aa)
ENSRBIP00000024420Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa)
ENSRBIP00000024768Uncharacterized protein; Belongs to the actin family. (156 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
ENSRBIP00000026615Uncharacterized protein. (185 aa)
ACTL7AActin like 7A; Belongs to the actin family. (395 aa)
ENSRBIP00000027876Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (353 aa)
ENSRBIP00000028717Uncharacterized protein. (173 aa)
ENSRBIP00000029649DH domain-containing protein. (251 aa)
ENSRBIP00000031488Uncharacterized protein. (67 aa)
FGRTyrosine-protein kinase. (529 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2009 aa)
YES1Tyrosine-protein kinase. (480 aa)
ACTG1Actin gamma 1. (377 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1051 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
LOC108516810Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (330 aa)
WASF1WASP family member 1. (559 aa)
VAV1Vav guanine nucleotide exchange factor 1. (843 aa)
NCKAP1NCK associated protein 1. (1112 aa)
WIPF1WAS/WASL interacting protein family member 1. (500 aa)
ENSRBIP00000035213Uncharacterized protein; Belongs to the actin family. (362 aa)
LYNTyrosine-protein kinase. (512 aa)
VAV3Uncharacterized protein. (287 aa)
ENSRBIP00000036977Protein kinase domain-containing protein. (68 aa)
WASF2WASP family member 2. (498 aa)
ELMO2Engulfment and cell motility 2. (718 aa)
CDC42Uncharacterized protein. (191 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
ENSRBIP00000037737annotation not available (191 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1930 aa)
BTKTyrosine-protein kinase. (673 aa)
WASWASP actin nucleation promoting factor. (455 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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