STRINGSTRING
SYK SYK FURIN FURIN ADCY4 ADCY4 ITPR2 ITPR2 GNG2 GNG2 ADCY3 ADCY3 RHBDF1 RHBDF1 ADCY9 ADCY9 GNG11 GNG11 GNG5 GNG5 GNG4 GNG4 GNB3 GNB3 AHCYL1 AHCYL1 GNB2 GNB2 ADCY7 ADCY7 GNAI1 GNAI1 ADAM17 ADAM17 CD163 CD163 PLCG2 PLCG2 PRKX PRKX ENSRBIP00000013012 ENSRBIP00000013012 ENSRBIP00000011770 ENSRBIP00000011770 GNAT3 GNAT3 DPEP2 DPEP2 GNG13 GNG13 GNG7 GNG7 ENSRBIP00000009458 ENSRBIP00000009458 GNAZ GNAZ RHBDF2 RHBDF2 CD3G CD3G ENSRBIP00000007423 ENSRBIP00000007423 GNB4 GNB4 SCART1 SCART1 FYN FYN GGT5 GGT5 ADCY6 ADCY6 GNG3 GNG3 HCK HCK SRC SRC CD247 CD247 PRKAR1A PRKAR1A PRKAR2A PRKAR2A DPEP1 DPEP1 ADCY2 ADCY2 ADCY8 ADCY8 PRKAR2B PRKAR2B ITPR1 ITPR1 DPEP3 DPEP3 ITPR3 ITPR3 IL6 IL6 IL10 IL10 GNAI3 GNAI3 GNG10 GNG10 PLCG1 PLCG1 MYH9 MYH9 GNGT2 GNGT2 ENSRBIP00000036977 ENSRBIP00000036977 PRKAR1B PRKAR1B GNAS GNAS LYN LYN ADCY1 ADCY1 GNB5 GNB5 PRKACB PRKACB ADORA2B ADORA2B ADCY5 ADCY5 CREB1 CREB1 LOC108516810 LOC108516810 YES1 YES1 GNG8 GNG8 GNB1 GNB1 FGR FGR GGTLC2 GGTLC2 GNG12 GNG12 GNAI2 GNAI2 LOC108538696 LOC108538696 PLK2 PLK2 MAPK14 MAPK14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYKUncharacterized protein. (331 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (787 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (102 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
RHBDF1Rhomboid 5 homolog 1. (890 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNB3G protein subunit beta 3. (340 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
GNB2G protein subunit beta 2. (368 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
GNAI1G protein subunit alpha i1. (331 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
CD163CD163 molecule. (1155 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PRKXProtein kinase X-linked. (261 aa)
ENSRBIP00000013012Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSRBIP00000011770Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
DPEP2Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (484 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSRBIP00000009458Uncharacterized protein. (297 aa)
GNAZG protein subunit alpha z. (355 aa)
RHBDF2Rhomboid 5 homolog 2. (891 aa)
CD3GCD3g molecule. (181 aa)
ENSRBIP00000007423Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GNB4G protein subunit beta 4. (340 aa)
SCART1Scavenger receptor family member expressed on T cells 1. (943 aa)
FYNTyrosine-protein kinase. (537 aa)
GGT5Gamma-glutamyltransferase 5. (448 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
HCKTyrosine-protein kinase. (517 aa)
SRCTyrosine-protein kinase. (627 aa)
CD247CD247 molecule. (165 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (376 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (411 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (412 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
DPEP3Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (513 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
IL6Interleukin 6. (214 aa)
IL10Interleukin 10. (178 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (62 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
ENSRBIP00000036977Protein kinase domain-containing protein. (68 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (452 aa)
GNASGNAS complex locus. (1041 aa)
LYNTyrosine-protein kinase. (512 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
GNB5G protein subunit beta 5. (403 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (394 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
LOC108516810Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (330 aa)
YES1Tyrosine-protein kinase. (480 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNB1G protein subunit beta 1. (340 aa)
FGRTyrosine-protein kinase. (529 aa)
GGTLC2Uncharacterized protein. (225 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNAI2G protein subunit alpha i2. (355 aa)
LOC108538696Uncharacterized protein. (351 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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