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REXO1 REXO1 POP7 POP7 POP1 POP1 NHP2 NHP2 GAR1 GAR1 NOB1 NOB1 UTP6 UTP6 NXT1 NXT1 LOC108517067 LOC108517067 SNU13 SNU13 IMP3 IMP3 WDR43 WDR43 MDN1 MDN1 UTP4 UTP4 DKC1 DKC1 GTPBP4 GTPBP4 NAT10 NAT10 LSG1 LSG1 FBL FBL CSNK2A2 CSNK2A2 RIOK2 RIOK2 NOP56 NOP56 RPP25L RPP25L EMG1 EMG1 GNL3 GNL3 MPHOSPH10 MPHOSPH10 SPATA5 SPATA5 NVL NVL DROSHA DROSHA EIF6 EIF6 RBM28 RBM28 PWP2 PWP2 AK6 AK6 FCF1 FCF1 BMS1 BMS1 LOC108520077 LOC108520077 SBDS SBDS RPP40 RPP40 RCL1 RCL1 XRN2 XRN2 RIOK1 RIOK1 WDR75 WDR75 RPP30 RPP30 CSNK2B CSNK2B REXO2 REXO2 RPP38 RPP38 GNL2 GNL2 WDR3 WDR3 UTP18 UTP18 HEATR1 HEATR1 NMD3 NMD3 NXF3 NXF3 EFL1 EFL1 WDR36 WDR36 GNL3L GNL3L XRN1 XRN1 NXF1 NXF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
REXO1RNA exonuclease 1 homolog. (1159 aa)
POP7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (1024 aa)
NHP2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa)
GAR1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (217 aa)
NOB1RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (412 aa)
UTP6UTP6 small subunit processome component. (598 aa)
NXT1Nuclear transport factor 2 like export factor 1. (140 aa)
LOC108517067Uncharacterized protein. (64 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (132 aa)
IMP3IMP U3 small nucleolar ribonucleoprotein 3. (184 aa)
WDR43WD repeat domain 43. (678 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5542 aa)
UTP4UTP4 small subunit processome component. (792 aa)
DKC1Dyskerin pseudouridine synthase 1. (597 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa)
LSG1Large 60S subunit nuclear export GTPase 1. (657 aa)
FBLFibrillarin. (320 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
RIOK2RIO kinase 2. (552 aa)
NOP56NOP56 ribonucleoprotein. (517 aa)
RPP25LRibonuclease P/MRP subunit p25 like. (163 aa)
EMG1EMG1 N1-specific pseudouridine methyltransferase. (244 aa)
GNL3G protein nucleolar 3. (549 aa)
MPHOSPH10U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (679 aa)
SPATA5Spermatogenesis associated 5. (892 aa)
NVLUncharacterized protein. (857 aa)
DROSHADrosha ribonuclease III. (1365 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
RBM28RNA binding motif protein 28. (763 aa)
PWP2Uncharacterized protein. (918 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
FCF1PINc domain-containing protein. (198 aa)
BMS1DUF663 domain-containing protein. (428 aa)
LOC108520077Uncharacterized protein. (523 aa)
SBDSSBDS ribosome maturation factor. (250 aa)
RPP40Ribonuclease P/MRP subunit p40. (363 aa)
RCL1RNA terminal phosphate cyclase like 1. (372 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (817 aa)
RIOK1Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (567 aa)
WDR75WD repeat domain 75. (830 aa)
RPP30Ribonuclease P/MRP subunit p30. (299 aa)
CSNK2BUncharacterized protein. (298 aa)
REXO2RNA exonuclease 2. (237 aa)
RPP38Uncharacterized protein. (144 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (731 aa)
WDR3WD repeat domain 3. (972 aa)
UTP18UTP18 small subunit processome component. (585 aa)
HEATR1HEAT repeat containing 1. (2142 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (492 aa)
NXF3Nuclear RNA export factor 3. (530 aa)
EFL1Elongation factor like GTPase 1. (1120 aa)
WDR36WD repeat domain 36. (922 aa)
GNL3LG protein nucleolar 3 like. (582 aa)
XRN15'-3' exoribonuclease 1. (1705 aa)
NXF1Nuclear RNA export factor 1. (619 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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