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NUP133 NUP133 LOC108533747 LOC108533747 KPNB1 KPNB1 POP7 POP7 NUP85 NUP85 SAP18 SAP18 EIF1B EIF1B POP1 POP1 NUP160 NUP160 GEMIN8 GEMIN8 NUP54 NUP54 EEF1A2 EEF1A2 PABPC5 PABPC5 UBE2I UBE2I PAIP1 PAIP1 ENSRBIP00000003512 ENSRBIP00000003512 NXT1 NXT1 ELAC2 ELAC2 EIF3F EIF3F NUP210 NUP210 NUP188 NUP188 SEC13 SEC13 LOC108523611 LOC108523611 XPO5 XPO5 NUP205 NUP205 EIF5B EIF5B LOC108537469 LOC108537469 EEF1A1 EEF1A1 PNN PNN EIF1 EIF1 NUP37 NUP37 ENSRBIP00000011829 ENSRBIP00000011829 EIF4EBP1 EIF4EBP1 LOC108530816 LOC108530816 PABPC4L PABPC4L PABPC1 PABPC1 EIF3B EIF3B DDX20 DDX20 RPP25L RPP25L ACIN1 ACIN1 RAE1 RAE1 ENSRBIP00000016866 ENSRBIP00000016866 LOC108515576 LOC108515576 NUP93 NUP93 NUP43 NUP43 SEH1L SEH1L CASC3 CASC3 SUMO3 SUMO3 PYM1 PYM1 THOC7 THOC7 THOC6 THOC6 EIF4A2 EIF4A2 SUMO2 SUMO2 THOC1 THOC1 PRMT5 PRMT5 UPF3A UPF3A EIF3F-2 EIF3F-2 MAGOHB MAGOHB PABPC3 PABPC3 GEMIN2 GEMIN2 FXR2 FXR2 STRAP STRAP TARDBP TARDBP LOC108520077 LOC108520077 EIF2B1 EIF2B1 PABPC1L PABPC1L CLNS1A CLNS1A SRRM1 SRRM1 THOC5 THOC5 LOC108517966 LOC108517966 RPP40 RPP40 EIF4G3 EIF4G3 GLE1 GLE1 EIF3I EIF3I RPP30 RPP30 LOC108541157 LOC108541157 EIF4G1 EIF4G1 DDX19B DDX19B UPF2 UPF2 NUP58 NUP58 NUP155 NUP155 RPP38 RPP38 NUP214 NUP214 EIF5 EIF5 LOC108529197 LOC108529197 SNUPN SNUPN RNPS1 RNPS1 EIF4E EIF4E RBM8A RBM8A EIF4E1B EIF4E1B ENSRBIP00000030956 ENSRBIP00000030956 NUP35 NUP35 THOC3 THOC3 EIF2B4 EIF2B4 ALYREF ALYREF EIF2B3 EIF2B3 PABPC4 PABPC4 EIF2B2 EIF2B2 NUP50 NUP50 GEMIN5 GEMIN5 NMD3 NMD3 NXF3 NXF3 AAAS AAAS EIF3H EIF3H MAGOH MAGOH XPOT XPOT EIF3D EIF3D EIF3G EIF3G TGS1 TGS1 GEMIN6 GEMIN6 TACC3 TACC3 NUP98 NUP98 CYFIP2 CYFIP2 NUP153 NUP153 GEMIN4 GEMIN4 NXF1 NXF1 TRNT1 TRNT1 ELAC1 ELAC1 EIF3E EIF3E EIF3A EIF3A NCBP1 NCBP1 EIF2S1 EIF2S1 NUP88 NUP88 RANBP2 RANBP2 EIF2B5 EIF2B5 POM121C POM121C EIF4B EIF4B LOC108523672 LOC108523672 EIF3J EIF3J PHAX PHAX EIF4EBP2 EIF4EBP2 EIF4A1 EIF4A1 NUP107 NUP107 EIF4E2 EIF4E2 NDC1 NDC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUP133Nucleoporin 133. (1129 aa)
LOC108533747Uncharacterized protein. (143 aa)
KPNB1Karyopherin subunit beta 1. (877 aa)
POP7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
SAP18Sin3A associated protein 18. (172 aa)
EIF1BEukaryotic translation initiation factor 1B. (113 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (1024 aa)
NUP160Nucleoporin 160. (1436 aa)
GEMIN8Gem nuclear organelle associated protein 8. (242 aa)
NUP54Nucleoporin 54. (509 aa)
EEF1A2Eukaryotic translation elongation factor 1 alpha 2. (604 aa)
PABPC5Poly(A) binding protein cytoplasmic 5. (382 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (231 aa)
PAIP1Poly(A) binding protein interacting protein 1. (400 aa)
ENSRBIP00000003512Small ubiquitin-related modifier. (95 aa)
NXT1Nuclear transport factor 2 like export factor 1. (140 aa)
ELAC2ElaC ribonuclease Z 2. (826 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (361 aa)
NUP210Nucleoporin 210. (1862 aa)
NUP188Nucleoporin 188. (1752 aa)
SEC13WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (368 aa)
LOC108523611Uncharacterized protein. (200 aa)
XPO5Exportin 5. (1204 aa)
NUP205Nucleoporin 205. (1995 aa)
EIF5BEukaryotic translation initiation factor 5B. (1209 aa)
LOC108537469Eukaryotic translation initiation factor 1A X-linked. (151 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
PNNPinin, desmosome associated protein. (719 aa)
EIF1Eukaryotic translation initiation factor 1. (113 aa)
NUP37Nucleoporin 37. (326 aa)
ENSRBIP00000011829WD_REPEATS_REGION domain-containing protein. (376 aa)
EIF4EBP1Uncharacterized protein. (118 aa)
LOC108530816Uncharacterized protein. (904 aa)
PABPC4LPoly(A) binding protein cytoplasmic 4 like. (370 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (626 aa)
EIF3BEukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form [...] (688 aa)
DDX20DEAD-box helicase 20. (825 aa)
RPP25LRibonuclease P/MRP subunit p25 like. (163 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1334 aa)
RAE1Ribonucleic acid export 1. (368 aa)
ENSRBIP00000016866Uncharacterized protein. (101 aa)
LOC108515576Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (346 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa)
NUP43WD_REPEATS_REGION domain-containing protein. (380 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (384 aa)
CASC3CASC3 exon junction complex subunit. (779 aa)
SUMO3Small ubiquitin-related modifier. (97 aa)
PYM1PYM homolog 1, exon junction complex associated factor. (197 aa)
THOC7THO complex 7. (175 aa)
THOC6THO complex 6. (341 aa)
EIF4A2Uncharacterized protein; Belongs to the DEAD box helicase family. (407 aa)
SUMO2Ubiquitin-like domain-containing protein. (80 aa)
THOC1THO complex 1. (664 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (630 aa)
UPF3AUPF3A regulator of nonsense mediated mRNA decay. (433 aa)
EIF3F-2Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (380 aa)
MAGOHBMago homolog B, exon junction complex subunit. (148 aa)
PABPC3Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (630 aa)
GEMIN2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (269 aa)
FXR2FMR1 autosomal homolog 2. (673 aa)
STRAPSerine/threonine kinase receptor associated protein. (363 aa)
TARDBPTAR DNA binding protein. (414 aa)
LOC108520077Uncharacterized protein. (523 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (306 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
CLNS1AUncharacterized protein. (237 aa)
SRRM1Serine and arginine repetitive matrix 1. (877 aa)
THOC5THO complex 5. (683 aa)
LOC108517966Eukaryotic translation initiation factor 1A Y-linked. (94 aa)
RPP40Ribonuclease P/MRP subunit p40. (363 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3. (1670 aa)
GLE1GLE1 RNA export mediator. (698 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (326 aa)
RPP30Ribonuclease P/MRP subunit p30. (299 aa)
LOC108541157Tudor domain-containing protein. (294 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1585 aa)
DDX19BDEAD-box helicase 19B. (484 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1257 aa)
NUP58Nucleoporin 58. (599 aa)
NUP155Nucleoporin 155. (1363 aa)
RPP38Uncharacterized protein. (144 aa)
NUP214Nucleoporin 214. (2060 aa)
EIF5W2 domain-containing protein. (431 aa)
LOC108529197Tr-type G domain-containing protein. (478 aa)
SNUPNSnurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family. (360 aa)
RNPS1RNA binding protein with serine rich domain 1. (282 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (240 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (173 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
ENSRBIP00000030956Small ubiquitin-related modifier. (123 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (326 aa)
THOC3THO complex 3. (351 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (544 aa)
ALYREFAly/REF export factor. (246 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (452 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
NUP50Nucleoporin 50. (468 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1507 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (492 aa)
NXF3Nuclear RNA export factor 3. (530 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (365 aa)
MAGOHMago homolog, exon junction complex subunit. (146 aa)
XPOTExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (962 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (548 aa)
EIF3GEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (321 aa)
TGS1Trimethylguanosine synthase 1. (843 aa)
GEMIN6Gem nuclear organelle associated protein 6. (167 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (812 aa)
NUP98Nucleoporin 98. (1799 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
NUP153Nucleoporin 153. (1466 aa)
GEMIN4Gem nuclear organelle associated protein 4. (1058 aa)
NXF1Nuclear RNA export factor 1. (619 aa)
TRNT1tRNA nucleotidyl transferase 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (423 aa)
ELAC1ElaC ribonuclease Z 1. (363 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (456 aa)
EIF3AEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (1345 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
NUP88Nucleoporin 88. (741 aa)
RANBP2RAN binding protein 2. (3174 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (721 aa)
POM121CUncharacterized protein. (1230 aa)
EIF4BEukaryotic translation initiation factor 4B. (617 aa)
LOC108523672Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (953 aa)
EIF3JEukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (209 aa)
PHAXRNA_GG_bind domain-containing protein. (442 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
EIF4A1Uncharacterized protein; Belongs to the DEAD box helicase family. (406 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
EIF4E2Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (244 aa)
NDC1NDC1 transmembrane nucleoporin. (674 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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