STRINGSTRING
CDS1 CDS1 CALML3 CALML3 PI4KA PI4KA PRKCG PRKCG IMPA1 IMPA1 PIK3R1 PIK3R1 PIK3R3 PIK3R3 DGKK DGKK MTMR8 MTMR8 CALML4 CALML4 PLCD1 PLCD1 ITPKB ITPKB IPMK IPMK PIK3C2B PIK3C2B INPP4B INPP4B PLCB1 PLCB1 MTMR1 MTMR1 MTMR2 MTMR2 CALM1 CALM1 MTMR6 MTMR6 IP6K3 IP6K3 PI4KB PI4KB INPP5E INPP5E DGKD DGKD PPIP5K2 PPIP5K2 PLCD4 PLCD4 ITPKA ITPKA IP6K2 IP6K2 INPP5F INPP5F DGKH DGKH PIP4K2B PIP4K2B ENSRBIP00000013200 ENSRBIP00000013200 PLCG2 PLCG2 INPP4A INPP4A PIK3C3 PIK3C3 ENSRBIP00000017741 ENSRBIP00000017741 PIK3CA PIK3CA IP6K1 IP6K1 DGKG DGKG INPP5D INPP5D PRKCA PRKCA SYNJ1 SYNJ1 MTMR3 MTMR3 PIK3C2G PIK3C2G ITPR2 ITPR2 PIP4K2C PIP4K2C ITPR1 ITPR1 INPP5B INPP5B PLCD3 PLCD3 DGKA DGKA MTM1 MTM1 HOGA1 HOGA1 SACM1L SACM1L IMPA2 IMPA2 PIK3C2A PIK3C2A INPP5A INPP5A MTMR4 MTMR4 PIP4P1 PIP4P1 CALM3 CALM3 INPPL1 INPPL1 DGKE DGKE IPPK IPPK PIP5K1A PIP5K1A CDS2 CDS2 PTEN PTEN PIK3CD PIK3CD OCRL OCRL PIP5K1B PIP5K1B PLCB2 PLCB2 PLCB4 PLCB4 PLCG1 PLCG1 MTMR14 MTMR14 DGKB DGKB MTMR7 MTMR7 DGKZ DGKZ CDIPT CDIPT PIKFYVE PIKFYVE SYNJ2 SYNJ2 ITPR3 ITPR3 DGKI DGKI PIP5K1C PIP5K1C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDS1Phosphatidate cytidylyltransferase; Belongs to the CDS family. (488 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2100 aa)
PRKCGProtein kinase C. (726 aa)
IMPA1Inositol-1-monophosphatase. (310 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
DGKKDiacylglycerol kinase. (1235 aa)
MTMR8Myotubularin related protein 8. (485 aa)
CALML4Calmodulin like 4. (192 aa)
PLCD1Phosphoinositide phospholipase C. (777 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (948 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (938 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
MTMR1Myotubularin related protein 1. (650 aa)
MTMR2Myotubularin related protein 2. (645 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
MTMR6Myotubularin related protein 6. (659 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (410 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (835 aa)
INPP5EInositol polyphosphate-5-phosphatase E. (537 aa)
DGKDDiacylglycerol kinase. (1216 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1285 aa)
PLCD4Phosphoinositide phospholipase C. (799 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (453 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (422 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1126 aa)
DGKHDiacylglycerol kinase. (1220 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
ENSRBIP00000013200Uncharacterized protein. (81 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (977 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (911 aa)
ENSRBIP00000017741Uncharacterized protein. (193 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
DGKGDiacylglycerol kinase. (791 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1194 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
SYNJ1Synaptojanin 1. (1614 aa)
MTMR3Myotubularin related protein 3. (1208 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1344 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (968 aa)
PLCD3Phosphoinositide phospholipase C. (785 aa)
DGKADiacylglycerol kinase. (749 aa)
MTM1Myotubularin 1. (534 aa)
HOGA1PI3K/PI4K domain-containing protein. (449 aa)
SACM1LSAC1 like phosphatidylinositide phosphatase. (587 aa)
IMPA2Inositol-1-monophosphatase. (292 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1635 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (412 aa)
MTMR4Myotubularin related protein 4. (1194 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)
CALM3Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1257 aa)
DGKEDiacylglycerol kinase. (566 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (491 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa)
PTENUncharacterized protein. (555 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (890 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (540 aa)
PLCB2Phosphoinositide phospholipase C. (991 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
MTMR14Myotubularin related protein 14. (650 aa)
DGKBDiacylglycerol kinase. (804 aa)
MTMR7Myotubularin related protein 7. (660 aa)
DGKZDiacylglycerol kinase. (1102 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (213 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2095 aa)
SYNJ2Synaptojanin 2. (1467 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
DGKIDiacylglycerol kinase. (944 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (376 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.