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CDKN1C | Uncharacterized protein. (142 aa) | ||||
CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) | ||||
YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (241 aa) | ||||
ESPL1 | Extra spindle pole bodies like 1, separase. (2120 aa) | ||||
STAG1 | Stromal antigen 1. (1219 aa) | ||||
CDC14A | Cell division cycle 14A. (619 aa) | ||||
ORC6 | Origin recognition complex subunit 6. (252 aa) | ||||
RBL2 | RB transcriptional corepressor like 2. (1127 aa) | ||||
E2F5 | E2F transcription factor 5. (345 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) | ||||
CDC20 | Cell division cycle 20. (499 aa) | ||||
LOC108544295 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) | ||||
CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) | ||||
SMC1A | Structural maintenance of chromosomes protein. (1233 aa) | ||||
ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) | ||||
YWHAQ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (253 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
CDC16 | Cell division cycle 16. (620 aa) | ||||
TFDP2 | Transcription factor. (429 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1149 aa) | ||||
BUB1 | BUB1 mitotic checkpoint serine/threonine kinase. (1096 aa) | ||||
ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (184 aa) | ||||
CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) | ||||
DBF4 | DBF4 zinc finger. (648 aa) | ||||
CCNB3 | Uncharacterized protein; Belongs to the cyclin family. (223 aa) | ||||
MAD1L1 | Mitotic arrest deficient 1 like 1. (766 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog. (467 aa) | ||||
BUB3 | WD_REPEATS_REGION domain-containing protein. (328 aa) | ||||
TFDP1 | Transcription factor. (410 aa) | ||||
CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) | ||||
PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa) | ||||
SMC1B | Structural maintenance of chromosomes protein. (1193 aa) | ||||
WEE2 | Wee1-like protein kinase. (567 aa) | ||||
ZBTB17 | Zinc finger and BTB domain containing 17. (803 aa) | ||||
CCNB1 | Cyclin B1; Belongs to the cyclin family. (433 aa) | ||||
LOC108527145 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) | ||||
PKMYT1 | Protein kinase, membrane associated tyrosine/threonine 1. (568 aa) | ||||
ORC2 | Origin recognition complex subunit 2. (575 aa) | ||||
SMAD4 | Mothers against decapentaplegic homolog. (552 aa) | ||||
CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
RB1 | RB transcriptional corepressor 1. (815 aa) | ||||
ENSRBIP00000020047 | Uncharacterized protein; Belongs to the SKP1 family. (162 aa) | ||||
CCNB2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3026 aa) | ||||
MCM2 | DNA helicase; Belongs to the MCM family. (907 aa) | ||||
CDC25B | Cell division cycle 25B. (580 aa) | ||||
HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) | ||||
MAD2L1 | HORMA domain-containing protein. (205 aa) | ||||
LOC108522364 | Uncharacterized protein. (389 aa) | ||||
GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) | ||||
RBL1 | RB transcriptional corepressor like 1. (1069 aa) | ||||
MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) | ||||
YWHAZ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (151 aa) | ||||
CDC23 | Cell division cycle 23. (597 aa) | ||||
HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) | ||||
CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa) | ||||
GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) | ||||
MCM3 | DNA helicase; Belongs to the MCM family. (828 aa) | ||||
CCND1 | Cyclin D1. (156 aa) | ||||
CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) | ||||
ANAPC5 | Anaphase promoting complex subunit 5. (755 aa) | ||||
ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2578 aa) | ||||
MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) | ||||
ORC5 | Origin recognition complex subunit 5. (424 aa) | ||||
CCND3 | Cyclin D3; Belongs to the cyclin family. (286 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) | ||||
CCNH | Cyclin H; Belongs to the cyclin family. (325 aa) | ||||
MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) | ||||
ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (435 aa) | ||||
CREBBP | CREB binding protein. (2422 aa) | ||||
SKP2 | S-phase kinase associated protein 2. (424 aa) | ||||
YWHAE | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa) | ||||
E2F2 | E2F transcription factor 2. (437 aa) | ||||
CDC14B | Cell division cycle 14B. (498 aa) | ||||
CDC14C | Cell division cycle 14C. (551 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) | ||||
FZR1 | Fizzy and cell division cycle 20 related 1. (496 aa) | ||||
EP300 | E1A binding protein p300. (2296 aa) | ||||
E2F4 | E2F transcription factor 4. (415 aa) | ||||
CDC7 | Cell division cycle 7. (574 aa) | ||||
CCNE2 | Cyclin E2; Belongs to the cyclin family. (403 aa) | ||||
ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) | ||||
CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) | ||||
CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa) | ||||
BUB1B | BUB1 N-terminal domain-containing protein. (1050 aa) | ||||
GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) | ||||
CCND2 | Uncharacterized protein; Belongs to the cyclin family. (244 aa) | ||||
E2F3 | E2F transcription factor 3. (465 aa) | ||||
RBX1 | Ring-box 1. (108 aa) | ||||
ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (807 aa) | ||||
SMC3 | Structural maintenance of chromosomes protein. (1208 aa) | ||||
CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) | ||||
ANAPC1 | Anaphase promoting complex subunit 1. (1944 aa) | ||||
CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) | ||||
ANAPC7 | Anaphase promoting complex subunit 7. (498 aa) | ||||
CDC26 | Cell division cycle 26. (85 aa) |