90 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	YWHAH	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (241 aa)
	ESPL1	Extra spindle pole bodies like 1, separase. (2120 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (310 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (524 aa)
	CDC20	Cell division cycle 20. (499 aa)
	LOC108544295	Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (758 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
	CALML4	Calmodulin like 4. (192 aa)
	YWHAQ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (253 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
	CDC16	Cell division cycle 16. (620 aa)
	PPP2R1B	Protein phosphatase 2 scaffold subunit Abeta. (667 aa)
	CAMK2D	Protein kinase domain-containing protein. (533 aa)
	IGF1	Insulin like growth factor 1. (208 aa)
	CPEB4	Uncharacterized protein. (401 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (149 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	CPEB2	Cytoplasmic polyadenylation element binding protein 2. (578 aa)
	BUB1	BUB1 mitotic checkpoint serine/threonine kinase. (1096 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (589 aa)
	ANAPC10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (184 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (520 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (766 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	PPP2R5B	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (595 aa)
	SMC1B	Structural maintenance of chromosomes protein. (1193 aa)
	RPS6KA3	Uncharacterized protein. (66 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (433 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	FBXO43	F-box protein 43. (688 aa)
	PKMYT1	Protein kinase, membrane associated tyrosine/threonine 1. (568 aa)
	LOC108522656	NR LBD domain-containing protein. (344 aa)
	ENSRBIP00000020047	Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
	CCNB2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
	PPP2R5E	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
	MAD2L1	HORMA domain-containing protein. (205 aa)
	MOS	MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (336 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
	ADCY8	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
	YWHAZ	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (151 aa)
	CDC23	Cell division cycle 23. (597 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
	ANAPC5	Anaphase promoting complex subunit 5. (755 aa)
	SLK	STE20 like kinase. (1225 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	SGO1	Shugoshin 1. (542 aa)
	PGR	Progesterone receptor. (935 aa)
	YWHAE	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa)
	FBXO5	F-box protein 5. (448 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	CALM3	Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
	SPDYC	Speedy/RINGO cell cycle regulator family member C. (293 aa)
	CCNE2	Cyclin E2; Belongs to the cyclin family. (403 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
	CAMK2A	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
	MAPK11	Mitogen-activated protein kinase. (364 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (716 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
	AURKA	Protein kinase domain-containing protein. (393 aa)
	SPDYA	Speedy/RINGO cell cycle regulator family member A. (313 aa)
	PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (571 aa)
	SPDYE4	Speedy/RINGO cell cycle regulator family member E4. (237 aa)
	RBX1	Ring-box 1. (108 aa)
	ANAPC4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (807 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
	SMC3	Structural maintenance of chromosomes protein. (1208 aa)
	STAG3	Stromal antigen 3. (1227 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1335 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
	ANAPC1	Anaphase promoting complex subunit 1. (1944 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (498 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	CDC26	Cell division cycle 26. (85 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSRBIP00000035296	ENSRBIP00000024365	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.458
ADCY1	ADCY3	ENSRBIP00000035296	ENSRBIP00000021747	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.944
ADCY1	ADCY5	ENSRBIP00000035296	ENSRBIP00000034265	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.429
ADCY1	ADCY6	ENSRBIP00000035296	ENSRBIP00000004607	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.429
ADCY1	ADCY7	ENSRBIP00000035296	ENSRBIP00000016019	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.488
ADCY1	ADCY8	ENSRBIP00000035296	ENSRBIP00000023627	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.957
ADCY1	ADCY9	ENSRBIP00000035296	ENSRBIP00000021122	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.672
ADCY1	CALM1	ENSRBIP00000035296	ENSRBIP00000008940	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 1; Belongs to the calmodulin family.	0.975
ADCY1	CALM3	ENSRBIP00000035296	ENSRBIP00000033152	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.945
ADCY1	CALML3	ENSRBIP00000035296	ENSRBIP00000000722	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 3; Belongs to the calmodulin family.	0.948
ADCY1	CALML4	ENSRBIP00000035296	ENSRBIP00000005029	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.937
ADCY1	CAMK2A	ENSRBIP00000035296	ENSRBIP00000034331	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily.	0.694
ADCY1	CAMK2D	ENSRBIP00000035296	ENSRBIP00000008494	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase domain-containing protein.	0.694
ADCY1	PRKACB	ENSRBIP00000035296	ENSRBIP00000034769	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.939
ADCY2	ADCY1	ENSRBIP00000024365	ENSRBIP00000035296	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.458
ADCY2	ADCY5	ENSRBIP00000024365	ENSRBIP00000034265	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.778
ADCY2	ADCY6	ENSRBIP00000024365	ENSRBIP00000004607	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.772
ADCY2	ADCY7	ENSRBIP00000024365	ENSRBIP00000016019	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.416
ADCY2	ADCY8	ENSRBIP00000024365	ENSRBIP00000023627	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.450
ADCY2	ADCY9	ENSRBIP00000024365	ENSRBIP00000021122	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.541