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UBE2G1 UBE2G1 LOC108541777 LOC108541777 BTRC BTRC RPS27A RPS27A RHOBTB2 RHOBTB2 MAP3K1 MAP3K1 SMURF2 SMURF2 SOCS1 SOCS1 ENSRBIP00000001317 ENSRBIP00000001317 UBE2E3 UBE2E3 UBE2I UBE2I UBE2O UBE2O KLHL13 KLHL13 UBE2W UBE2W CDC20 CDC20 LOC108544295 LOC108544295 BIRC3 BIRC3 RHOBTB1 RHOBTB1 CBLB CBLB ELOB ELOB HERC4 HERC4 LOC108540530 LOC108540530 LOC108520651 LOC108520651 UBE2G2 UBE2G2 UBE2F-SCLY UBE2F-SCLY PRKN PRKN CDC16 CDC16 UBA52 UBA52 KLHL9 KLHL9 UBE2Q1 UBE2Q1 UBE2M UBE2M CUL3 CUL3 ANAPC10 ANAPC10 STUB1 STUB1 LOC108531561 LOC108531561 LOC108525766 LOC108525766 BIRC2 BIRC2 HERC3 HERC3 UBOX5 UBOX5 UBE2S UBE2S TRIM32 TRIM32 SOCS3 SOCS3 CUL1 CUL1 CBLC CBLC UBE2L3 UBE2L3 UBE2L6 UBE2L6 PIAS3 PIAS3 UBE2QL1 UBE2QL1 CUL5 CUL5 UBA2 UBA2 UBE2D1 UBE2D1 UBE2D2 UBE2D2 KEAP1 KEAP1 SIAH1 SIAH1 UBE2R2 UBE2R2 DDB1 DDB1 ENSRBIP00000020047 ENSRBIP00000020047 UBA1 UBA1 UBE2E1 UBE2E1 VHL VHL UBE2H UBE2H HUWE1 HUWE1 AIRE AIRE HERC1 HERC1 BIRC6 BIRC6 LOC108523192 LOC108523192 PIAS1 PIAS1 FANCL FANCL UBE3C UBE3C FBXW7 FBXW7 CDC23 CDC23 ITCH ITCH DDB2 DDB2 UBA6 UBA6 ERCC8 ERCC8 MID1 MID1 ANAPC5 ANAPC5 NEDD4L NEDD4L SAE1 SAE1 PIAS2 PIAS2 UBE2Z UBE2Z FBXO2 FBXO2 ELOC ELOC UBR5 UBR5 SKP2 SKP2 CUL7 CUL7 WWP1 WWP1 UBE4A UBE4A UBE2D4 UBE2D4 UBE3A UBE3A FZR1 FZR1 UBE2J1 UBE2J1 ANAPC2 ANAPC2 PML PML TRAF6 TRAF6 UBE2Q2 UBE2Q2 TRIP12 TRIP12 SYVN1 SYVN1 TRIM37 TRIM37 PIAS4 PIAS4 FBXO4 FBXO4 UBE2A UBE2A UBE3B UBE3B UBE4B UBE4B WWP2 WWP2 RBX1 RBX1 ANAPC4 ANAPC4 BRCA1 BRCA1 UBA7 UBA7 COP1 COP1 UBA3 UBA3 ANAPC1 ANAPC1 UBE2U UBE2U DET1 DET1 RNF7 RNF7 ANAPC7 ANAPC7 CDC26 CDC26 BIRC7 BIRC7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
LOC108541777UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
RHOBTB2Rho related BTB domain containing 2. (749 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1374 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (719 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
UBE2E3Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (231 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1324 aa)
KLHL13Kelch like family member 13. (537 aa)
UBE2WUBIQUITIN_CONJUGAT_2 domain-containing protein. (209 aa)
CDC20Cell division cycle 20. (499 aa)
LOC108544295Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
RHOBTB1Rho related BTB domain containing 1. (696 aa)
CBLBCbl proto-oncogene B. (1018 aa)
ELOBUbiquitin-like domain-containing protein. (195 aa)
HERC4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (964 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
LOC108520651UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
UBE2F-SCLYUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
CDC16Cell division cycle 16. (620 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
KLHL9Kelch like family member 9. (612 aa)
UBE2Q1Ubiquitin conjugating enzyme E2 Q1. (411 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
CUL3Cullin 3; Belongs to the cullin family. (715 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (184 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
LOC108531561Ubiquitin-like domain-containing protein. (118 aa)
LOC108525766Uncharacterized protein. (80 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
HERC3HECT domain-containing protein. (1050 aa)
UBOX5U-box domain containing 5. (541 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
TRIM32Tripartite motif containing 32. (653 aa)
SOCS3Uncharacterized protein. (225 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
CBLCCbl proto-oncogene C. (436 aa)
UBE2L3Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (211 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PIAS3Protein inhibitor of activated STAT 3. (634 aa)
UBE2QL1Ubiquitin conjugating enzyme E2 Q family like 1. (161 aa)
CUL5Cullin 5; Belongs to the cullin family. (774 aa)
UBA2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (635 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
KEAP1Kelch like ECH associated protein 1. (368 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
UBE2R2Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (234 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
ENSRBIP00000020047Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
UBA1Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1058 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
VHLVon Hippel-Lindau tumor suppressor. (213 aa)
UBE2HUbiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4151 aa)
AIREAutoimmune regulator. (523 aa)
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4758 aa)
BIRC6Baculoviral IAP repeat containing 6. (4838 aa)
LOC108523192UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (101 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
FANCLFA complementation group L. (383 aa)
UBE3CUbiquitin protein ligase E3C. (1076 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
CDC23Cell division cycle 23. (597 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
UBA6Ubiquitin like modifier activating enzyme 6. (849 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (370 aa)
MID1Midline 1. (667 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1227 aa)
SAE1SUMO1 activating enzyme subunit 1. (346 aa)
PIAS2Protein inhibitor of activated STAT 2. (620 aa)
UBE2ZUbiquitin conjugating enzyme E2 Z. (227 aa)
FBXO2F-box protein 2. (298 aa)
ELOCSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2727 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
CUL7Cullin 7; Belongs to the cullin family. (1763 aa)
WWP1E3 ubiquitin-protein ligase. (810 aa)
UBE4AUbiquitination factor E4A. (1072 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (173 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
FZR1Fizzy and cell division cycle 20 related 1. (496 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (317 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
PMLPromyelocytic leukemia. (932 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
UBE2Q2Ubiquitin conjugating enzyme E2 Q2. (375 aa)
TRIP12Thyroid hormone receptor interactor 12. (2048 aa)
SYVN1Synoviolin 1. (616 aa)
TRIM37Tripartite motif containing 37. (951 aa)
PIAS4Protein inhibitor of activated STAT 4. (508 aa)
FBXO4F-box protein 4. (375 aa)
UBE2AUBIQUITIN_CONJUGAT_2 domain-containing protein. (63 aa)
UBE3BUbiquitin protein ligase E3B. (1068 aa)
UBE4BUbiquitination factor E4B. (1265 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
RBX1Ring-box 1. (108 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (807 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1818 aa)
UBA7Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1013 aa)
COP1COP1 E3 ubiquitin ligase. (725 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (463 aa)
ANAPC1Anaphase promoting complex subunit 1. (1944 aa)
UBE2UUbiquitin conjugating enzyme E2 U; Belongs to the ubiquitin-conjugating enzyme family. (318 aa)
DET1Uncharacterized protein. (561 aa)
RNF7RING-type domain-containing protein. (113 aa)
ANAPC7Anaphase promoting complex subunit 7. (498 aa)
CDC26Cell division cycle 26. (85 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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