STRINGSTRING
MAML2 MAML2 HEYL HEYL DTX4 DTX4 LOC108514577 LOC108514577 PTCRA PTCRA HEY1 HEY1 DLL1 DLL1 JAG2 JAG2 DLL3 DLL3 KAT2A KAT2A LFNG LFNG DTX3 DTX3 ATXN1 ATXN1 RFNG RFNG DVL3 DVL3 NOTCH4 NOTCH4 JAG1 JAG1 ADAM17 ADAM17 NCSTN NCSTN MAML3 MAML3 LOC108527145 LOC108527145 DVL2 DVL2 NUMBL NUMBL DTX2 DTX2 APH1B APH1B PSENEN PSENEN LOC108532941 LOC108532941 HDAC1 HDAC1 HEY2 HEY2 APH1A APH1A HDAC2 HDAC2 MFNG MFNG HES5 HES5 NCOR2 NCOR2 CREBBP CREBBP DTX3L DTX3L PSEN2 PSEN2 RBPJ RBPJ EP300 EP300 CTBP2 CTBP2 NOTCH2 NOTCH2 SNW1 SNW1 RBPJL RBPJL NUMB NUMB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAML2Mastermind like transcriptional coactivator 2. (1147 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
DTX4Deltex E3 ubiquitin ligase 4. (619 aa)
LOC108514577AXH domain-containing protein. (689 aa)
PTCRAPre T cell antigen receptor alpha. (281 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (748 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1075 aa)
DLL3Delta like canonical Notch ligand 3. (618 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (349 aa)
DTX3Deltex E3 ubiquitin ligase 3. (349 aa)
ATXN1Ataxin 1. (804 aa)
RFNGRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (317 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
NOTCH4Notch receptor 4. (2000 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
NCSTNNicastrin. (709 aa)
MAML3Mastermind like transcriptional coactivator 3. (1129 aa)
LOC108527145Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
DVL2Dishevelled segment polarity protein 2. (735 aa)
NUMBLNUMB like endocytic adaptor protein. (606 aa)
DTX2Deltex E3 ubiquitin ligase 2. (622 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
LOC108532941Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (450 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
HES5Hes family bHLH transcription factor 5. (152 aa)
NCOR2Nuclear receptor corepressor 2. (2488 aa)
CREBBPCREB binding protein. (2422 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (744 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (531 aa)
EP300E1A binding protein p300. (2296 aa)
CTBP2C-terminal binding protein 2. (988 aa)
NOTCH2Notch receptor 2. (2532 aa)
SNW1SKIP_SNW domain-containing protein. (536 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (522 aa)
NUMBNUMB endocytic adaptor protein. (652 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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