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ND1 ND1 ND2 ND2 ND3 ND3 ND4L ND4L ND4 ND4 ND5 ND5 ND6 ND6 MAPK3 MAPK3 CACNA1B CACNA1B NDUFB5 NDUFB5 PRKCG PRKCG GRIA4 GRIA4 SLC17A7 SLC17A7 DAGLB DAGLB NDUFC2 NDUFC2 NDUFAB1 NDUFAB1 MAPK10 MAPK10 NAPEPLD NAPEPLD NDUFB2 NDUFB2 CACNA1A CACNA1A KCNJ5 KCNJ5 NDUFS1 NDUFS1 ADCY6 ADCY6 GABRB3 GABRB3 NDUFB3 NDUFB3 GABRG3 GABRG3 NDUFS8 NDUFS8 CACNA1S CACNA1S GNB4 GNB4 SLC17A8 SLC17A8 MAPK9 MAPK9 PLCB1 PLCB1 ENSRBIP00000007423 ENSRBIP00000007423 GABRA1 GABRA1 NDUFA4 NDUFA4 NDUFA12 NDUFA12 LOC108526074 LOC108526074 GNG7 GNG7 NDUFS2 NDUFS2 GNG13 GNG13 NDUFC1 NDUFC1 GABRA5 GABRA5 SLC32A1 SLC32A1 NDUFB7 NDUFB7 KCNJ3 KCNJ3 GABRB1 GABRB1 GRM5 GRM5 ADCY7 ADCY7 GABRR3 GABRR3 NDUFA2 NDUFA2 NDUFS4 NDUFS4 GNB3 GNB3 NDUFA8 NDUFA8 GNG4 GNG4 GNG5 GNG5 NDUFV3 NDUFV3 NDUFB1 NDUFB1 GABRR2 GABRR2 FAAH FAAH GABRR1 GABRR1 GNG11 GNG11 PRKCA PRKCA ABHD6 ABHD6 GABRP GABRP RIMS1 RIMS1 ADCY9 ADCY9 CACNA1D CACNA1D ADCY3 ADCY3 KCNJ9 KCNJ9 GNG2 GNG2 ITPR2 ITPR2 NDUFA9 NDUFA9 PTGS2 PTGS2 GABRQ GABRQ ITPR1 ITPR1 ENSRBIP00000023424 ENSRBIP00000023424 ADCY8 ADCY8 GABRG1 GABRG1 DAGLA DAGLA ADCY2 ADCY2 NDUFB8 NDUFB8 GNG3 GNG3 GABRA4 GABRA4 MAPK1 MAPK1 GABRD GABRD MAPK14 MAPK14 NDUFA10-2 NDUFA10-2 NDUFA4L2 NDUFA4L2 GNAI2 GNAI2 NDUFV1 NDUFV1 GRIA2 GRIA2 GNG12 GNG12 KCNJ6 KCNJ6 NDUFV2 NDUFV2 NDUFB9 NDUFB9 GNB1 GNB1 NDUFB6 NDUFB6 GNG8 GNG8 MAPK13 MAPK13 ADCY5 ADCY5 MAPK11 MAPK11 GRIA1 GRIA1 PRKACB PRKACB GNB5 GNB5 CACNA1F CACNA1F ADCY1 ADCY1 GABRA3 GABRA3 NDUFA7 NDUFA7 MGLL MGLL GNAQ GNAQ GABRA2 GABRA2 PLCB2 PLCB2 PLCB4 PLCB4 ENSRBIP00000038945 ENSRBIP00000038945 NDUFA6 NDUFA6 NDUFB4 NDUFB4 CNR1 CNR1 SLC17A6 SLC17A6 GNAI3 GNAI3 GABRA6 GABRA6 ITPR3 ITPR3 NDUFB10 NDUFB10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ND1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (318 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (603 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (174 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2299 aa)
NDUFB5Uncharacterized protein. (189 aa)
PRKCGProtein kinase C. (726 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
DAGLBDiacylglycerol lipase beta. (701 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (119 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
MAPK10Mitogen-activated protein kinase. (528 aa)
NAPEPLDUncharacterized protein. (77 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (105 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2305 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (507 aa)
NDUFB3Uncharacterized protein. (98 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (210 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
GNB4G protein subunit beta 4. (340 aa)
SLC17A8Solute carrier family 17 member 8. (588 aa)
MAPK9Mitogen-activated protein kinase. (407 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
ENSRBIP00000007423Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (81 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
LOC108526074Uncharacterized protein. (89 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
NDUFS2Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (550 aa)
GNG13G protein subunit gamma 13. (67 aa)
NDUFC1NADH:ubiquinone oxidoreductase subunit C1. (76 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
SLC32A1Solute carrier family 32 member 1. (525 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (137 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
GRM5Glutamate metabotropic receptor 5. (1212 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
NDUFA2NADH:ubiquinone oxidoreductase subunit A2. (105 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (133 aa)
GNB3G protein subunit beta 3. (340 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
NDUFV3NADH:ubiquinone oxidoreductase subunit V3. (473 aa)
NDUFB1Uncharacterized protein. (58 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
FAAHFatty acid amide hydrolase. (637 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (479 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
ABHD6Abhydrolase domain containing 6. (336 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1693 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (102 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (377 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (632 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
ENSRBIP00000023424Uncharacterized protein. (64 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (375 aa)
DAGLADiacylglycerol lipase alpha. (1040 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (554 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
NDUFA10-2dNK domain-containing protein. (323 aa)
NDUFA4L2NDUFA4 mitochondrial complex associated like 2. (94 aa)
GNAI2G protein subunit alpha i2. (355 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (414 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (244 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (202 aa)
GNB1G protein subunit beta 1. (340 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (113 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (899 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GNB5G protein subunit beta 5. (403 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1818 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (308 aa)
NDUFA7Uncharacterized protein. (113 aa)
MGLLMonoglyceride lipase. (313 aa)
GNAQG protein subunit alpha q. (359 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (427 aa)
PLCB2Phosphoinositide phospholipase C. (991 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
ENSRBIP00000038945Uncharacterized protein. (141 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (129 aa)
CNR1Uncharacterized protein. (36 aa)
SLC17A6Solute carrier family 17 member 6. (582 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (172 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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