92 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DLGAP1	DLG associated protein 1. (543 aa)
	GRM3	Glutamate metabotropic receptor 3. (879 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
	PLA2G4B	Phospholipase A2. (781 aa)
	PRKCG	Protein kinase C. (726 aa)
	GRIA4	Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
	PLA2G4F	Phospholipase A2. (827 aa)
	SLC17A7	Solute carrier family 17 member 7. (560 aa)
	GRM7	Glutamate metabotropic receptor 7. (922 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (310 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (524 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
	GRM8	Glutamate metabotropic receptor 8. (908 aa)
	CACNA1A	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2305 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
	TRPC1	Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (724 aa)
	GNB4	G protein subunit beta 4. (340 aa)
	SLC17A8	Solute carrier family 17 member 8. (588 aa)
	HOMER1	Homer scaffold protein 1. (374 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
	ENSRBIP00000007423	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	GRIK4	Glutamate ionotropic receptor kainate type subunit 4. (956 aa)
	GLS	Glutaminase. (669 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	GNG13	G protein subunit gamma 13. (67 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (520 aa)
	GRM2	Glutamate metabotropic receptor 2. (872 aa)
	GRIK1	Glutamate ionotropic receptor kainate type subunit 1. (949 aa)
	PLA2G4C	Phospholipase A2 group IVC. (551 aa)
	KCNJ3	Potassium voltage-gated channel subfamily J member 3. (501 aa)
	SLC1A2	Amino acid transporter. (574 aa)
	PLA2G4A	Phospholipase A2. (738 aa)
	GRM5	Glutamate metabotropic receptor 5. (1212 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	GRIN2C	Glutamate ionotropic receptor NMDA type subunit 2C. (1242 aa)
	GLS2	Glutaminase 2. (602 aa)
	GNB3	G protein subunit beta 3. (340 aa)
	SLC38A2	Solute carrier family 38 member 2. (506 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	GLUL	Glutamine synthetase. (373 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A. (1139 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
	SLC38A1	Solute carrier family 38 member 1. (503 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
	SLC1A1	Amino acid transporter. (524 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (102 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
	SLC1A6	Amino acid transporter. (564 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
	ADCY8	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
	GRK2	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (690 aa)
	PLA2G4E	Phospholipase A2. (869 aa)
	GRIK3	Glutamate ionotropic receptor kainate type subunit 3. (919 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
	GRM4	Glutamate metabotropic receptor 4. (912 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (755 aa)
	HOMER2	Homer scaffold protein 2. (384 aa)
	HOMER3	WH1 domain-containing protein. (361 aa)
	GNAI2	G protein subunit alpha i2. (355 aa)
	GRIA2	Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
	GRIK5	Glutamate ionotropic receptor kainate type subunit 5. (980 aa)
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	SLC38A3	Solute carrier family 38 member 3. (504 aa)
	GNB1	G protein subunit beta 1. (340 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	GRK3	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (687 aa)
	SHANK2	SH3 and multiple ankyrin repeat domains 2. (1850 aa)
	PLA2G4D	Phospholipase A2. (816 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (899 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	GNB5	G protein subunit beta 5. (403 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
	SLC1A3	Amino acid transporter. (542 aa)
	GRIN2D	Glutamate ionotropic receptor NMDA type subunit 2D; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1079 aa)
	GNAS	GNAS complex locus. (1041 aa)
	GNAQ	G protein subunit alpha q. (359 aa)
	PLCB2	Phosphoinositide phospholipase C. (991 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
	GRIN1	Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
	SLC17A6	Solute carrier family 17 member 6. (582 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	PLD1	Phospholipase. (968 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
	LOC108541626	Uncharacterized protein. (246 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSRBIP00000035296	ENSRBIP00000024365	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.458
ADCY1	ADCY3	ENSRBIP00000035296	ENSRBIP00000021747	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.944
ADCY1	ADCY5	ENSRBIP00000035296	ENSRBIP00000034265	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.429
ADCY1	ADCY6	ENSRBIP00000035296	ENSRBIP00000004607	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.429
ADCY1	ADCY7	ENSRBIP00000035296	ENSRBIP00000016019	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.488
ADCY1	ADCY8	ENSRBIP00000035296	ENSRBIP00000023627	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.957
ADCY1	ADCY9	ENSRBIP00000035296	ENSRBIP00000021122	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.672
ADCY1	ENSRBIP00000007423	ENSRBIP00000035296	ENSRBIP00000007423	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.802
ADCY1	GNAI2	ENSRBIP00000035296	ENSRBIP00000030098	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.940
ADCY1	GNAI3	ENSRBIP00000035296	ENSRBIP00000040755	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.942
ADCY1	GNAS	ENSRBIP00000035296	ENSRBIP00000036792	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.970
ADCY1	GNB1	ENSRBIP00000035296	ENSRBIP00000032151	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 1.	0.798
ADCY1	GNB3	ENSRBIP00000035296	ENSRBIP00000017763	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 3.	0.789
ADCY1	GNB4	ENSRBIP00000035296	ENSRBIP00000006724	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 4.	0.798
ADCY1	GNB5	ENSRBIP00000035296	ENSRBIP00000034869	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 5.	0.859
ADCY1	GNG11	ENSRBIP00000035296	ENSRBIP00000019700	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.851
ADCY1	GNG12	ENSRBIP00000035296	ENSRBIP00000030798	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.801
ADCY1	GNG13	ENSRBIP00000035296	ENSRBIP00000010334	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit gamma 13.	0.869
ADCY1	GNG2	ENSRBIP00000035296	ENSRBIP00000022343	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.827
ADCY1	GNG3	ENSRBIP00000035296	ENSRBIP00000026084	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.784