99 items (Rhinopithecus bieti) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	CACNA1B	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2299 aa)
	PRKCG	Protein kinase C. (726 aa)
	GRIA4	Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
	LOC108523462	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (446 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (310 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (524 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
	ARRB2	Arrestin beta 2. (466 aa)
	MAPK10	Mitogen-activated protein kinase. (528 aa)
	CREB3L2	cAMP responsive element binding protein 3 like 2. (520 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	CACNA1A	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2305 aa)
	KCNJ5	Potassium voltage-gated channel subfamily J member 5. (419 aa)
	CALML4	Calmodulin like 4. (192 aa)
	ATF6B	Activating transcription factor 6 beta. (708 aa)
	GSK3A	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (444 aa)
	GNB4	G protein subunit beta 4. (340 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
	MAPK9	Mitogen-activated protein kinase. (407 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
	ENSRBIP00000007423	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	PPP2R1B	Protein phosphatase 2 scaffold subunit Abeta. (667 aa)
	CAMK2D	Protein kinase domain-containing protein. (533 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (149 aa)
	PPP2R2A	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (589 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	GNG13	G protein subunit gamma 13. (67 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (520 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (442 aa)
	DDC	Dopa decarboxylase. (494 aa)
	SLC18A1	Solute carrier family 18 member A1. (525 aa)
	PPP2R5B	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (595 aa)
	CALY	Calcyon neuron specific vesicular protein. (217 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
	KCNJ3	Potassium voltage-gated channel subfamily J member 3. (501 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	GNB3	G protein subunit beta 3. (340 aa)
	SCN1A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1943 aa)
	PPP2R2C	Protein phosphatase 2 regulatory subunit Bgamma. (282 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
	KIF5A	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1033 aa)
	PPP2R5E	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
	KCNJ9	Potassium voltage-gated channel subfamily J member 9. (393 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (102 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
	COMT	Catechol-O-methyltransferase. (373 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
	CREB3	cAMP responsive element binding protein 3. (370 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	PPP2R2D	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa)
	LOC108543739	Uncharacterized protein. (282 aa)
	KIF5C	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	GNAI2	G protein subunit alpha i2. (355 aa)
	PPP2R3A	Protein phosphatase 2 regulatory subunit B''alpha. (1098 aa)
	GRIA2	Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	KCNJ6	Potassium voltage-gated channel subfamily J member 6. (414 aa)
	CREB5	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (503 aa)
	GNB1	G protein subunit beta 1. (340 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	CALM3	Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
	AKT3	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
	CAMK2A	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
	MAPK11	Mitogen-activated protein kinase. (364 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (899 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	GNB5	G protein subunit beta 5. (403 aa)
	CLOCK	Clock circadian regulator. (847 aa)
	ARRB1	Arrestin beta 1. (418 aa)
	GNAS	GNAS complex locus. (1041 aa)
	GNAQ	G protein subunit alpha q. (359 aa)
	PPP2R2B	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
	PLCB2	Phosphoinositide phospholipase C. (991 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
	PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (571 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	CREB3L3	cAMP responsive element binding protein 3 like 3. (483 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
	LOC108541626	Uncharacterized protein. (246 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	AKT2	ENSRBIP00000034265	ENSRBIP00000034007	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.916
ADCY5	AKT3	ENSRBIP00000034265	ENSRBIP00000034274	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily.	0.911
ADCY5	CALM1	ENSRBIP00000034265	ENSRBIP00000008940	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 1; Belongs to the calmodulin family.	0.705
ADCY5	CALM3	ENSRBIP00000034265	ENSRBIP00000033152	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.705
ADCY5	CALML3	ENSRBIP00000034265	ENSRBIP00000000722	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 3; Belongs to the calmodulin family.	0.718
ADCY5	CALML4	ENSRBIP00000034265	ENSRBIP00000005029	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.722
ADCY5	CAMK2A	ENSRBIP00000034265	ENSRBIP00000034331	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily.	0.667
ADCY5	CAMK2D	ENSRBIP00000034265	ENSRBIP00000008494	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase domain-containing protein.	0.667
ADCY5	ENSRBIP00000007423	ENSRBIP00000034265	ENSRBIP00000007423	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.936
ADCY5	GNAI2	ENSRBIP00000034265	ENSRBIP00000030098	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.935
ADCY5	GNAI3	ENSRBIP00000034265	ENSRBIP00000040755	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.934
ADCY5	GNAS	ENSRBIP00000034265	ENSRBIP00000036792	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.974
ADCY5	GNB1	ENSRBIP00000034265	ENSRBIP00000032151	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 1.	0.933
ADCY5	GNB3	ENSRBIP00000034265	ENSRBIP00000017763	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 3.	0.935
ADCY5	GNB4	ENSRBIP00000034265	ENSRBIP00000006724	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 4.	0.933
ADCY5	GNB5	ENSRBIP00000034265	ENSRBIP00000034869	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 5.	0.944
ADCY5	GNG11	ENSRBIP00000034265	ENSRBIP00000019700	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.949
ADCY5	GNG12	ENSRBIP00000034265	ENSRBIP00000030798	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.936
ADCY5	GNG13	ENSRBIP00000034265	ENSRBIP00000010334	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit gamma 13.	0.943
ADCY5	GNG2	ENSRBIP00000034265	ENSRBIP00000022343	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.944