STRINGSTRING
MAPK3 MAPK3 PLA2G4B PLA2G4B CRH CRH PRKCG PRKCG PLA2G4F PLA2G4F ENSRBIP00000002156 ENSRBIP00000002156 CACNA1A CACNA1A GNA11 GNA11 PLCB1 PLCB1 PPP2R1B PPP2R1B GNAZ GNAZ IGF1 IGF1 ARAF ARAF GNA13 GNA13 PPP2R1A PPP2R1A RAF1 RAF1 PLA2G4C PLA2G4C MAP2K1 MAP2K1 PLA2G4A PLA2G4A GNA12 GNA12 PPP1R17 PPP1R17 PRKCA PRKCA BRAF BRAF HRAS HRAS ITPR2 ITPR2 ITPR1 ITPR1 PRKG2 PRKG2 PLA2G4E PLA2G4E MAPK1 MAPK1 NOS1 NOS1 KRAS KRAS GUCY1A1 GUCY1A1 GNAI2 GNAI2 GRIA2 GRIA2 PLA2G4D PLA2G4D GRIA1 GRIA1 LYN LYN GNAS GNAS GNAQ GNAQ PLCB2 PLCB2 PLCB4 PLCB4 RYR1 RYR1 NRAS NRAS GNAI3 GNAI3 LOC108541626 LOC108541626 ITPR3 ITPR3 IGF1R IGF1R PPP2CA PPP2CA GRID2 GRID2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
PLA2G4BPhospholipase A2. (781 aa)
CRHCorticotropin releasing hormone. (196 aa)
PRKCGProtein kinase C. (726 aa)
PLA2G4FPhospholipase A2. (827 aa)
ENSRBIP00000002156Uncharacterized protein. (366 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2305 aa)
GNA11G protein subunit alpha 11. (354 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
GNAZG protein subunit alpha z. (355 aa)
IGF1Insulin like growth factor 1. (208 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
GNA13G protein subunit alpha 13. (353 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
RAF1Uncharacterized protein. (668 aa)
PLA2G4CPhospholipase A2 group IVC. (551 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PLA2G4APhospholipase A2. (738 aa)
GNA12G protein subunit alpha 12. (322 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (154 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (753 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
PRKG2cGMP-dependent protein kinase. (725 aa)
PLA2G4EPhospholipase A2. (869 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1333 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GNAI2G protein subunit alpha i2. (355 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
PLA2G4DPhospholipase A2. (816 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (899 aa)
LYNTyrosine-protein kinase. (512 aa)
GNASGNAS complex locus. (1041 aa)
GNAQG protein subunit alpha q. (359 aa)
PLCB2Phosphoinositide phospholipase C. (991 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
RYR1Ryanodine receptor 1. (4866 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GNAI3G protein subunit alpha i3. (354 aa)
LOC108541626Uncharacterized protein. (246 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (926 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (10%) [HD]