STRINGSTRING
PLA2G4B PLA2G4B CALML3 CALML3 PRKCG PRKCG PLA2G4F PLA2G4F PIK3R1 PIK3R1 SRC SRC PIK3R3 PIK3R3 MAPK10 MAPK10 HRH1 HRH1 ASIC4 ASIC4 ADCY6 ADCY6 CALML4 CALML4 MAPK9 MAPK9 PLCB1 PLCB1 KNG1 KNG1 CAMK2D CAMK2D TRPA1 TRPA1 PTGER4 PTGER4 IGF1 IGF1 CALM1 CALM1 IL1R1 IL1R1 PPP1CB PPP1CB LOC108543807 LOC108543807 PLCG2 PLCG2 PLA2G4C PLA2G4C PPP1CC PPP1CC PLA2G4A PLA2G4A ADCY7 ADCY7 MAP2K3 MAP2K3 IL1B IL1B PIK3CA PIK3CA PRKCA PRKCA CYP2J2 CYP2J2 MAP2K6 MAP2K6 ADCY9 ADCY9 ADCY3 ADCY3 ASIC3 ASIC3 ITPR2 ITPR2 PRKCD PRKCD ASIC5 ASIC5 ITPR1 ITPR1 ADCY8 ADCY8 ADCY2 ADCY2 PLA2G4E PLA2G4E F2RL1 F2RL1 MAPK14 MAPK14 LOC108535621 LOC108535621 HTR2A HTR2A TRPM8 TRPM8 PRKCQ PRKCQ ASIC2 ASIC2 MAPK13 MAPK13 CALM3 CALM3 PLA2G4D PLA2G4D ADCY5 ADCY5 CAMK2A CAMK2A MAPK11 MAPK11 PRKACB PRKACB PIK3CD PIK3CD ADCY1 ADCY1 IL1RAP IL1RAP TRPV4 TRPV4 GNAS GNAS GNAQ GNAQ PLCB2 PLCB2 PLCB4 PLCB4 PLCG1 PLCG1 PLA2G6 PLA2G6 TRPV3 TRPV3 NTRK1 NTRK1 TRPV1 TRPV1 PRKCE PRKCE NGF NGF PPP1CA PPP1CA LOC108541626 LOC108541626 ITPR3 ITPR3 HTR2B HTR2B PTGER2 PTGER2 PRKCH PRKCH ALOX12 ALOX12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLA2G4BPhospholipase A2. (781 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
PRKCGProtein kinase C. (726 aa)
PLA2G4FPhospholipase A2. (827 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SRCTyrosine-protein kinase. (627 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
MAPK10Mitogen-activated protein kinase. (528 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (489 aa)
ASIC4Acid sensing ion channel subunit family member 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (594 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
CALML4Calmodulin like 4. (192 aa)
MAPK9Mitogen-activated protein kinase. (407 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
KNG1Kininogen 1. (644 aa)
CAMK2DProtein kinase domain-containing protein. (533 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1084 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
IGF1Insulin like growth factor 1. (208 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
IL1R1Interleukin 1 receptor type 1. (568 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
LOC108543807Uncharacterized protein. (474 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PLA2G4CPhospholipase A2 group IVC. (551 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
PLA2G4APhospholipase A2. (738 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (541 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ASIC5Acid sensing ion channel subunit family member 5; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (505 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PLA2G4EPhospholipase A2. (869 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
LOC108535621Uncharacterized protein; Belongs to the cytochrome P450 family. (519 aa)
HTR2A5-hydroxytryptamine receptor 2A. (472 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
ASIC2Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (512 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
CALM3Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
PLA2G4DPhospholipase A2. (816 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
IL1RAPInterleukin 1 receptor accessory protein. (680 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
GNASGNAS complex locus. (1041 aa)
GNAQG protein subunit alpha q. (359 aa)
PLCB2Phosphoinositide phospholipase C. (991 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
NTRK1Tyrosine-protein kinase receptor. (816 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (839 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (123 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
LOC108541626Uncharacterized protein. (246 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (663 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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