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GPR119 GPR119 PRKCG PRKCG SLC2A2 SLC2A2 CHRM3 CHRM3 CREB3L2 CREB3L2 KCNJ11 KCNJ11 ATP1A1 ATP1A1 GNA11 GNA11 ADCY6 ADCY6 ATF6B ATF6B CACNA1S CACNA1S PLCB1 PLCB1 RYR2 RYR2 ATP1B3 ATP1B3 CAMK2D CAMK2D ABCC8 ABCC8 ATP1A4 ATP1A4 RAB3A RAB3A CREB3L1 CREB3L1 FFAR1 FFAR1 KCNMB1 KCNMB1 INS INS ADCY7 ADCY7 ATF4 ATF4 ADCYAP1 ADCYAP1 PRKCA PRKCA SLC2A1 SLC2A1 ADCY9 ADCY9 CACNA1D CACNA1D GCK GCK ADCY3 ADCY3 ADCY8 ADCY8 CREB3 CREB3 SNAP25 SNAP25 ADCY2 ADCY2 KCNN3 KCNN3 PCLO PCLO GCG GCG CCK CCK TRPM4 TRPM4 ATP1B4 ATP1B4 ADCYAP1R1 ADCYAP1R1 GLP1R GLP1R KCNN1 KCNN1 PDX1 PDX1 CREB5 CREB5 GIP GIP KCNMB2 KCNMB2 STX1A STX1A ATP1B1 ATP1B1 CREB1 CREB1 ADCY5 ADCY5 CAMK2A CAMK2A PRKACB PRKACB CACNA1F CACNA1F ADCY1 ADCY1 KCNN2 KCNN2 GNAS GNAS GNAQ GNAQ PLCB2 PLCB2 RAPGEF4 RAPGEF4 KCNU1 KCNU1 PLCB4 PLCB4 CREB3L3 CREB3L3 ATP1B2 ATP1B2 CCKAR CCKAR LOC108541626 LOC108541626 ITPR3 ITPR3 VAMP2 VAMP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPR119G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa)
PRKCGProtein kinase C. (726 aa)
SLC2A2MFS domain-containing protein. (115 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1034 aa)
GNA11G protein subunit alpha 11. (354 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
ATF6BActivating transcription factor 6 beta. (708 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
RYR2Ryanodine receptor 2. (4866 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (265 aa)
CAMK2DProtein kinase domain-containing protein. (533 aa)
ABCC8ATP binding cassette subfamily C member 8. (1585 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
RAB3ARAB3A, member RAS oncogene family. (187 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (442 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
ATF4Activating transcription factor 4. (351 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
GCKPhosphotransferase. (466 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
CREB3cAMP responsive element binding protein 3. (370 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (749 aa)
PCLOUncharacterized protein. (1217 aa)
GCGGlucagon. (180 aa)
CCKCholecystokinin. (115 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1052 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (577 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (528 aa)
PDX1Pancreatic and duodenal homeobox 1. (284 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (503 aa)
GIPGastric inhibitory polypeptide. (151 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1818 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (845 aa)
GNASGNAS complex locus. (1041 aa)
GNAQG protein subunit alpha q. (359 aa)
PLCB2Phosphoinositide phospholipase C. (991 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (882 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1149 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (483 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
LOC108541626Uncharacterized protein. (246 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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