STRINGSTRING
PLA2G4B PLA2G4B PLA2G4F PLA2G4F ADCY6 ADCY6 LOC108536227 LOC108536227 CYP1B1 CYP1B1 IGF1 IGF1 AKR1C3 AKR1C3 LHCGR LHCGR BMP6 BMP6 HSD17B1 HSD17B1 PLA2G4C PLA2G4C CYP11A1 CYP11A1 BMP15 BMP15 PLA2G4A PLA2G4A AKR1C8P AKR1C8P ALOX5 ALOX5 INS INS ADCY7 ADCY7 STAR STAR LDLR LDLR HSD3B1 HSD3B1 CYP2J2 CYP2J2 ADCY9 ADCY9 HSD17B7 HSD17B7 ADCY3 ADCY3 PTGS2 PTGS2 ADCY8 ADCY8 ADCY2 ADCY2 PLA2G4E PLA2G4E FSHB FSHB LHB-2 LHB-2 HSD17B2 HSD17B2 HSD3B2 HSD3B2 PLA2G4D PLA2G4D ADCY5 ADCY5 PRKACB PRKACB CYP17A1 CYP17A1 ADCY1 ADCY1 SCARB1 SCARB1 GNAS GNAS CYP1A1 CYP1A1 CYP19A1 CYP19A1 LOC108541626 LOC108541626 IGF1R IGF1R
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLA2G4BPhospholipase A2. (781 aa)
PLA2G4FPhospholipase A2. (827 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
LOC108536227Uncharacterized protein. (415 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
IGF1Insulin like growth factor 1. (208 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (343 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (645 aa)
BMP6Bone morphogenetic protein 6. (440 aa)
HSD17B1Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)
PLA2G4CPhospholipase A2 group IVC. (551 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
PLA2G4APhospholipase A2. (738 aa)
AKR1C8PAldo-keto reductase family 1 member C8, pseudogene. (323 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
STARSteroidogenic acute regulatory protein. (294 aa)
LDLRLow density lipoprotein receptor. (819 aa)
HSD3B1Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (373 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
HSD17B7Hydroxysteroid 17-beta dehydrogenase 7. (369 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PLA2G4EPhospholipase A2. (869 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
LHB-2Cys_knot domain-containing protein. (141 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa)
HSD3B2Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2; Belongs to the 3-beta-HSD family. (373 aa)
PLA2G4DPhospholipase A2. (816 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
CYP17A1Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (508 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (553 aa)
GNASGNAS complex locus. (1041 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
LOC108541626Uncharacterized protein. (246 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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