STRINGSTRING
MAPK3 MAPK3 CALML3 CALML3 TCF7L2 TCF7L2 PRKCG PRKCG WNT6 WNT6 WNT3 WNT3 POMC POMC CREB3L2 CREB3L2 MITF MITF FZD9 FZD9 ADCY6 ADCY6 FZD5 FZD5 CALML4 CALML4 FZD10 FZD10 WNT2B WNT2B PLCB1 PLCB1 TYRP1 TYRP1 CAMK2D CAMK2D CALM1 CALM1 LEF1 LEF1 DVL3 DVL3 RAF1 RAF1 TCF7 TCF7 TCF7L1 TCF7L1 CREB3L1 CREB3L1 FZD7 FZD7 MAP2K1 MAP2K1 WNT10B WNT10B DVL2 DVL2 ADCY7 ADCY7 PRKCA PRKCA ADCY9 ADCY9 EDNRB EDNRB ADCY3 ADCY3 HRAS HRAS CTNNB1 CTNNB1 WNT8B WNT8B ADCY8 ADCY8 CREB3 CREB3 GSK3B GSK3B ADCY2 ADCY2 WNT16 WNT16 WNT9A WNT9A WNT5B WNT5B WNT8A WNT8A MAPK1 MAPK1 KRAS KRAS EDN1 EDN1 WNT9B WNT9B FZD4 FZD4 KIT KIT GNAI2 GNAI2 CREBBP CREBBP ASIP ASIP WNT3A WNT3A CALM3 CALM3 FZD3 FZD3 WNT1 WNT1 EP300 EP300 WNT7B WNT7B TYR TYR CREB1 CREB1 MC1R MC1R ADCY5 ADCY5 CAMK2A CAMK2A PRKACB PRKACB ADCY1 ADCY1 GNAS GNAS GNAQ GNAQ PLCB2 PLCB2 PLCB4 PLCB4 WNT11 WNT11 NRAS NRAS WNT7A WNT7A GNAI3 GNAI3 CREB3L3 CREB3L3 WNT5A WNT5A LOC108541626 LOC108541626 WNT2 WNT2 FZD6 FZD6 WNT10A WNT10A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
TCF7L2HMG box domain-containing protein. (376 aa)
PRKCGProtein kinase C. (726 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
POMCProopiomelanocortin. (251 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
MITFMelanocyte inducing transcription factor. (517 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
CALML4Calmodulin like 4. (192 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
TYRP1Tyrosinase related protein 1. (519 aa)
CAMK2DProtein kinase domain-containing protein. (533 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
LEF1Lymphoid enhancer binding factor 1. (398 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
RAF1Uncharacterized protein. (668 aa)
TCF7Transcription factor 7. (399 aa)
TCF7L1Transcription factor 7 like 1. (440 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (442 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
DVL2Dishevelled segment polarity protein 2. (735 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (507 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CTNNB1Catenin beta 1. (781 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
CREB3cAMP responsive element binding protein 3. (370 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (467 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
EDN1Endothelin 1. (211 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
GNAI2G protein subunit alpha i2. (355 aa)
CREBBPCREB binding protein. (2422 aa)
ASIPAgouti signaling protein. (132 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CALM3Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
EP300E1A binding protein p300. (2296 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
TYRTyrosinase. (530 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (304 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
GNASGNAS complex locus. (1041 aa)
GNAQG protein subunit alpha q. (359 aa)
PLCB2Phosphoinositide phospholipase C. (991 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (344 aa)
GNAI3G protein subunit alpha i3. (354 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (483 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LOC108541626Uncharacterized protein. (246 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (647 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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