56 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
	SOCS1	Suppressor of cytokine signaling 1. (215 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	SLC2A2	MFS domain-containing protein. (115 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	SRC	Tyrosine-protein kinase. (627 aa)
	PIK3R3	Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
	MAPK10	Mitogen-activated protein kinase. (528 aa)
	SOCS4	Suppressor of cytokine signaling 4. (439 aa)
	MAPK9	Mitogen-activated protein kinase. (407 aa)
	IRF1	Interferon regulatory factor. (325 aa)
	TNFRSF11A	TNF receptor superfamily member 11a. (614 aa)
	SOCS2	Suppressor of cytokine signaling 2. (233 aa)
	SHC2	Uncharacterized protein. (421 aa)
	LHCGR	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (645 aa)
	RAF1	Uncharacterized protein. (668 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (969 aa)
	SOCS5	Suppressor of cytokine signaling 5. (536 aa)
	SOCS3	Uncharacterized protein. (225 aa)
	PRL	Prolactin. (227 aa)
	SHC4	SHC adaptor protein 4. (630 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	ELF5	E74 like ETS transcription factor 5. (265 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	STAT5B	Signal transducer and activator of transcription. (768 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	CSN2	Beta-casein; Important role in determination of the surface properties of the casein micelles. (226 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
	RELA	Uncharacterized protein. (282 aa)
	GCK	Phosphotransferase. (466 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	SOCS7	Suppressor of cytokine signaling 7. (579 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member. (317 aa)
	PRLR	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
	CCND1	Cyclin D1. (156 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	ESR2	Estrogen receptor 2. (530 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	LHB-2	Cys_knot domain-containing protein. (141 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1293 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	AKT3	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
	MAPK11	Mitogen-activated protein kinase. (364 aa)
	FOXO3	Forkhead box O3. (672 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
	CYP17A1	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (508 aa)
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2. (1268 aa)
	STAT1	Signal transducer and activator of transcription. (787 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	CCND2	Uncharacterized protein; Belongs to the cyclin family. (244 aa)
	SHC1	SHC adaptor protein 1. (584 aa)
	SHC3	SHC adaptor protein 3. (596 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT2	AKT3	ENSRBIP00000034007	ENSRBIP00000034274	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily.	0.939
AKT2	FOXO3	ENSRBIP00000034007	ENSRBIP00000034643	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O3.	0.974
AKT2	GSK3B	ENSRBIP00000034007	ENSRBIP00000024352	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.962
AKT2	INS	ENSRBIP00000034007	ENSRBIP00000015729	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.521
AKT2	MAPK1	ENSRBIP00000034007	ENSRBIP00000026426	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.932
AKT2	MAPK11	ENSRBIP00000034007	ENSRBIP00000034454	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.933
AKT2	MAPK13	ENSRBIP00000034007	ENSRBIP00000032970	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.931
AKT2	MAPK14	ENSRBIP00000034007	ENSRBIP00000027919	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.933
AKT2	MAPK3	ENSRBIP00000034007	ENSRBIP00000000532	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.940
AKT2	PIK3CA	ENSRBIP00000034007	ENSRBIP00000017817	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.967
AKT2	PIK3CD	ENSRBIP00000034007	ENSRBIP00000035123	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.954
AKT2	PIK3R1	ENSRBIP00000034007	ENSRBIP00000001603	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase regulatory subunit 1.	0.960
AKT2	PIK3R3	ENSRBIP00000034007	ENSRBIP00000002180	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase regulatory subunit 3.	0.948
AKT2	RAF1	ENSRBIP00000034007	ENSRBIP00000010874	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.926
AKT2	SRC	ENSRBIP00000034007	ENSRBIP00000002089	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.547
AKT2	STAT1	ENSRBIP00000034007	ENSRBIP00000036941	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Signal transducer and activator of transcription.	0.410
AKT3	AKT2	ENSRBIP00000034274	ENSRBIP00000034007	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.939
AKT3	FOXO3	ENSRBIP00000034274	ENSRBIP00000034643	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily.	Forkhead box O3.	0.969
AKT3	GSK3B	ENSRBIP00000034274	ENSRBIP00000024352	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.960
AKT3	INS	ENSRBIP00000034274	ENSRBIP00000015729	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.442