STRINGSTRING
PRKCG PRKCG DUOX2 DUOX2 IYD IYD CREB3L2 CREB3L2 ATP1A1 ATP1A1 GPX5 GPX5 SLC5A5 SLC5A5 ADCY6 ADCY6 GPX6 GPX6 ATF6B ATF6B PLCB1 PLCB1 ATP1B3 ATP1B3 ATP1A4 ATP1A4 GPX2 GPX2 LRP2 LRP2 CREB3L1 CREB3L1 SLC26A4 SLC26A4 TSHB TSHB DUOX1 DUOX1 ADCY7 ADCY7 ATF4 ATF4 TPO TPO HSP90B1 HSP90B1 GPX7 GPX7 PAX8 PAX8 PRKCA PRKCA ADCY9 ADCY9 ADCY3 ADCY3 TG TG ITPR2 ITPR2 ITPR1 ITPR1 ADCY8 ADCY8 CREB3 CREB3 SERPINA7 SERPINA7 GPX8 GPX8 ADCY2 ADCY2 ASGR1 ASGR1 ATP1B4 ATP1B4 GPX1 GPX1 CREB5 CREB5 TSHR TSHR PDIA4 PDIA4 ATP1B1 ATP1B1 CREB1 CREB1 ADCY5 ADCY5 PRKACB PRKACB ADCY1 ADCY1 DUOXA2 DUOXA2 GNAS GNAS GNAQ GNAQ PLCB2 PLCB2 TTF2 TTF2 PLCB4 PLCB4 CREB3L3 CREB3L3 ATP1B2 ATP1B2 LOC108541626 LOC108541626 ITPR3 ITPR3 HSPA5 HSPA5 GPX3 GPX3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCGProtein kinase C. (726 aa)
DUOX2Dual oxidase 2. (1548 aa)
IYDIodotyrosine deiodinase. (292 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1034 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (643 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
GPX6Glutathione peroxidase 6. (219 aa)
ATF6BActivating transcription factor 6 beta. (708 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (265 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (150 aa)
LRP2LDL receptor related protein 2. (4655 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (442 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
TSHBThyroid stimulating hormone subunit beta. (138 aa)
DUOX1Dual oxidase 1. (1551 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
ATF4Activating transcription factor 4. (351 aa)
TPOThyroid peroxidase. (933 aa)
HSP90B1Heat shock protein 90 beta family member 1. (799 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (193 aa)
PAX8Paired box 8. (484 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
TGThyroglobulin. (2750 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
CREB3cAMP responsive element binding protein 3. (370 aa)
SERPINA7Serpin family A member 7; Belongs to the serpin family. (415 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
ASGR1Asialoglycoprotein receptor 1. (291 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (200 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (503 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
PDIA4Protein disulfide-isomerase. (657 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
DUOXA2Dual oxidase maturation factor 2. (320 aa)
GNASGNAS complex locus. (1041 aa)
GNAQG protein subunit alpha q. (359 aa)
PLCB2Phosphoinositide phospholipase C. (991 aa)
TTF2Transcription termination factor 2. (1170 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (483 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
LOC108541626Uncharacterized protein. (246 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
HSPA5Heat shock protein family A (Hsp70) member 5. (467 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (225 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: medium (52%) [HD]