STRINGSTRING
PRKAG3 PRKAG3 POMC POMC MAPK10 MAPK10 MTOR MTOR STK11 STK11 MAPK9 MAPK9 PPARA PPARA PRKAG1 PRKAG1 CD36 CD36 ACSL3 ACSL3 PRKAB2 PRKAB2 TNF TNF ACSL6 ACSL6 ADIPOQ ADIPOQ ACSBG2 ACSBG2 NFKB1 NFKB1 SOCS3 SOCS3 IRS1 IRS1 IKBKG IKBKG IRS2 IRS2 PPARGC1A PPARGC1A ACSBG1 ACSBG1 PCK1 PCK1 RELA RELA TRADD TRADD NFKBIB NFKBIB SLC2A4 SLC2A4 PRKAB1 PRKAB1 SLC2A1 SLC2A1 CPT1C CPT1C ADIPOR1 ADIPOR1 G6PC3 G6PC3 ACSL1 ACSL1 CHUK CHUK TNFRSF1B TNFRSF1B PRKAA1 PRKAA1 IKBKB IKBKB LEPR LEPR RXRG RXRG PRKCQ PRKCQ TRAF2 TRAF2 RXRB RXRB ACSL5 ACSL5 AKT2 AKT2 AKT3 AKT3 PCK2 PCK2 ACACB ACACB ADIPOR2 ADIPOR2 IRS4 IRS4 PRKAA2 PRKAA2 RXRA RXRA G6PC G6PC TNFRSF1A TNFRSF1A NFKBIA NFKBIA NPY NPY LEP LEP CAMKK2 CAMKK2 AGRP AGRP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
POMCProopiomelanocortin. (251 aa)
MAPK10Mitogen-activated protein kinase. (528 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2527 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
MAPK9Mitogen-activated protein kinase. (407 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (704 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ACSL6AMP-binding domain-containing protein. (722 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (275 aa)
ACSBG2Acyl-CoA synthetase bubblegum family member 2. (705 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
SOCS3Uncharacterized protein. (225 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa)
IRS2Insulin receptor substrate 2. (904 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (758 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
RELAUncharacterized protein. (282 aa)
TRADDTNFRSF1A associated via death domain. (248 aa)
NFKBIBNFKB inhibitor beta. (338 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (766 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (721 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
LEPRLeptin receptor. (1169 aa)
RXRGRetinoid X receptor gamma. (463 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
RXRBRetinoid X receptor beta. (508 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (600 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
AKT3AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
ADIPOR2Adiponectin receptor 2. (337 aa)
IRS4Insulin receptor substrate 4. (1247 aa)
PRKAA2Non-specific serine/threonine protein kinase. (539 aa)
RXRARetinoid X receptor alpha. (492 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
NPYNeuropeptide Y. (97 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (588 aa)
AGRPAgouti related neuropeptide. (132 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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