44 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

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protein homology

Your Input:
	ABHD5	Abhydrolase domain containing 5. (349 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	PIK3R3	Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
	PNPLA2	Patatin like phospholipase domain containing 2. (872 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
	ADORA1	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
	LIPE	Lipase E, hormone sensitive type. (929 aa)
	TSHB	Thyroid stimulating hormone subunit beta. (138 aa)
	IRS1	Insulin receptor substrate 1. (1241 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	PLAAT3	Phospholipase A and acyltransferase 3. (161 aa)
	IRS2	Insulin receptor substrate 2. (904 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
	PTGS1	Prostaglandin-endoperoxide synthase 1. (632 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
	PTGER3	Prostaglandin E receptor 3. (418 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (604 aa)
	FABP9	Fatty acid binding protein 9; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
	ADCY8	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
	PRKG2	cGMP-dependent protein kinase. (725 aa)
	GNAI2	G protein subunit alpha i2. (355 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
	NPR1	Guanylate cyclase. (1061 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
	AKT3	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
	MGLL	Monoglyceride lipase. (313 aa)
	GNAS	GNAS complex locus. (1041 aa)
	IRS4	Insulin receptor substrate 4. (1247 aa)
	PLIN1	Perilipin; Belongs to the perilipin family. (513 aa)
	PLAAT2	Phospholipase A and acyltransferase 2. (164 aa)
	NPY1R	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
	FABP4	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (112 aa)
	AQP7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (348 aa)
	NPY	Neuropeptide Y. (97 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	LOC108541626	Uncharacterized protein. (246 aa)
	ADRB2	Adrenoceptor beta 2. (399 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD5	LIPE	ENSRBIP00000001040	ENSRBIP00000006128	Abhydrolase domain containing 5.	Lipase E, hormone sensitive type.	0.582
ABHD5	MGLL	ENSRBIP00000001040	ENSRBIP00000036456	Abhydrolase domain containing 5.	Monoglyceride lipase.	0.445
ABHD5	PLIN1	ENSRBIP00000001040	ENSRBIP00000037162	Abhydrolase domain containing 5.	Perilipin; Belongs to the perilipin family.	0.933
ABHD5	PNPLA2	ENSRBIP00000001040	ENSRBIP00000003217	Abhydrolase domain containing 5.	Patatin like phospholipase domain containing 2.	0.973
ADCY1	ADCY2	ENSRBIP00000035296	ENSRBIP00000024365	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.458
ADCY1	ADCY3	ENSRBIP00000035296	ENSRBIP00000021747	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.944
ADCY1	ADCY5	ENSRBIP00000035296	ENSRBIP00000034265	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.429
ADCY1	ADCY6	ENSRBIP00000035296	ENSRBIP00000004607	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.429
ADCY1	ADCY7	ENSRBIP00000035296	ENSRBIP00000016019	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.488
ADCY1	ADCY8	ENSRBIP00000035296	ENSRBIP00000023627	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.957
ADCY1	ADCY9	ENSRBIP00000035296	ENSRBIP00000021122	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.672
ADCY1	AKT2	ENSRBIP00000035296	ENSRBIP00000034007	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.911
ADCY1	AKT3	ENSRBIP00000035296	ENSRBIP00000034274	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily.	0.911
ADCY1	GNAI2	ENSRBIP00000035296	ENSRBIP00000030098	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.940
ADCY1	GNAI3	ENSRBIP00000035296	ENSRBIP00000040755	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.942
ADCY1	GNAS	ENSRBIP00000035296	ENSRBIP00000036792	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.970
ADCY1	LOC108541626	ENSRBIP00000035296	ENSRBIP00000041615	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.903
ADCY1	PRKACB	ENSRBIP00000035296	ENSRBIP00000034769	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.939
ADCY2	ADCY1	ENSRBIP00000024365	ENSRBIP00000035296	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.458
ADCY2	ADCY5	ENSRBIP00000024365	ENSRBIP00000034265	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.778