STRINGSTRING
SREBF1 SREBF1 NR1H3 NR1H3 PPP1R3B PPP1R3B PRKAG3 PRKAG3 OGT OGT PIK3R1 PIK3R1 SLC2A2 SLC2A2 PIK3R3 PIK3R3 PTPN1 PTPN1 MAPK10 MAPK10 CREB3L2 CREB3L2 RPS6KA2 RPS6KA2 MLXIP MLXIP MTOR MTOR FOXO1 FOXO1 SLC27A5 SLC27A5 MAPK9 MAPK9 PPARA PPARA RPS6KA1 RPS6KA1 PRKAG1 PRKAG1 CD36 CD36 PPP1CB PPP1CB PRKAB2 PRKAB2 TNF TNF CREB3L1 CREB3L1 NFKB1 NFKB1 SOCS3 SOCS3 SLC27A1 SLC27A1 IRS1 IRS1 SLC27A3 SLC27A3 RPS6KA3 RPS6KA3 PPP1CC PPP1CC INS INS IRS2 IRS2 PPARGC1A PPARGC1A PCK1 PCK1 PIK3CA PIK3CA PYGM PYGM RELA RELA GYS1 GYS1 GFPT2 GFPT2 SLC2A4 SLC2A4 SLC27A2 SLC27A2 PRKAB1 PRKAB1 SLC2A1 SLC2A1 GYS2 GYS2 CRTC2 CRTC2 G6PC3 G6PC3 NR1H2 NR1H2 PRKCD PRKCD MLX MLX GFPT1 GFPT1 CREB3 CREB3 GSK3B GSK3B PPP1R3D PPP1R3D PRKAA1 PRKAA1 PPARGC1B PPARGC1B IKBKB IKBKB PPP1R3E PPP1R3E PRKCQ PRKCQ CREB5 CREB5 TRIB3 TRIB3 CREB1 CREB1 AKT2 AKT2 NOS3 NOS3 AKT3 AKT3 PTPRF PTPRF PTEN PTEN PIK3CD PIK3CD PCK2 PCK2 ACACB ACACB PPP1R3A PPP1R3A SLC27A6 SLC27A6 OGA OGA PRKAA2 PRKAA2 G6PC G6PC PYGB PYGB TNFRSF1A TNFRSF1A NFKBIA NFKBIA CREB3L3 CREB3L3 PRKCE PRKCE PPP1CA PPP1CA IL6 IL6 PYGL PYGL PPP1R3C PPP1R3C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SREBF1Sterol regulatory element binding transcription factor 1. (1047 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (441 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (285 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (886 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SLC2A2MFS domain-containing protein. (115 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
MAPK10Mitogen-activated protein kinase. (528 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
MLXIPMLX interacting protein. (919 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2527 aa)
FOXO1Forkhead box O1. (539 aa)
SLC27A5Solute carrier family 27 member 5. (690 aa)
MAPK9Mitogen-activated protein kinase. (407 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (442 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
SOCS3Uncharacterized protein. (225 aa)
SLC27A1Solute carrier family 27 member 1. (651 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
SLC27A3Solute carrier family 27 member 3. (730 aa)
RPS6KA3Uncharacterized protein. (66 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
IRS2Insulin receptor substrate 2. (904 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
RELAUncharacterized protein. (282 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
GFPT2Glutamine-fructose-6-phosphate transaminase 2. (688 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
SLC27A2Solute carrier family 27 member 2. (620 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
CRTC2CREB regulated transcription coactivator 2. (699 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
MLXMAX dimerization protein MLX. (298 aa)
GFPT1Glutamine--fructose-6-phosphate transaminase 1. (655 aa)
CREB3cAMP responsive element binding protein 3. (370 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit. (294 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
PPARGC1BPPARG coactivator 1 beta. (1024 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
PPP1R3EProtein phosphatase 1 regulatory subunit 3E. (266 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (503 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
AKT3AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1912 aa)
PTENUncharacterized protein. (555 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1118 aa)
SLC27A6Solute carrier family 27 member 6. (619 aa)
OGAO-GlcNAcase. (942 aa)
PRKAA2Non-specific serine/threonine protein kinase. (539 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (884 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (483 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
IL6Interleukin 6. (214 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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