STRINGSTRING
PDE1B PDE1B CACNA1B CACNA1B PRKCG PRKCG LOC108523462 LOC108523462 PDE2A PDE2A ARRB2 ARRB2 CACNA1A CACNA1A KCNJ5 KCNJ5 ADCY6 ADCY6 GABRB3 GABRB3 ADORA1 ADORA1 PDE10A PDE10A PDE8B PDE8B GABRG3 GABRG3 GNB4 GNB4 ENSRBIP00000007423 ENSRBIP00000007423 GABRA1 GABRA1 LOC108534220 LOC108534220 GNG7 GNG7 GNG13 GNG13 PDE1C PDE1C GRK6 GRK6 GABRA5 GABRA5 SLC32A1 SLC32A1 KCNJ3 KCNJ3 GABRB1 GABRB1 ADCY7 ADCY7 GABRR3 GABRR3 GNB3 GNB3 GNG4 GNG4 GNG5 GNG5 GABRR2 GABRR2 GABRR1 GABRR1 GNG11 GNG11 GRK5 GRK5 PRKCA PRKCA GABRP GABRP ADCY9 ADCY9 GRK4 GRK4 ADCY3 ADCY3 KCNJ9 KCNJ9 GNG2 GNG2 GABRQ GABRQ ADCY8 ADCY8 GABRG1 GABRG1 ADCY2 ADCY2 PDE4A PDE4A GRK2 GRK2 GNG3 GNG3 GABRA4 GABRA4 GABRD GABRD PDE1A PDE1A GNAI2 GNAI2 GNG12 GNG12 KCNJ6 KCNJ6 PDE7A PDE7A OPRM1 OPRM1 GNB1 GNB1 GABBR1 GABBR1 GNG8 GNG8 GRK3 GRK3 ADCY5 ADCY5 PRKACB PRKACB GNB5 GNB5 ADCY1 ADCY1 ARRB1 ARRB1 GABRA3 GABRA3 GNAS GNAS GABBR2 GABBR2 GABRA2 GABRA2 PDE4B PDE4B PDE11A PDE11A PDE8A PDE8A GNAI3 GNAI3 GABRA6 GABRA6 PDE4D PDE4D LOC108541626 LOC108541626 PDE7B PDE7B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDE1BPhosphodiesterase. (536 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2299 aa)
PRKCGProtein kinase C. (726 aa)
LOC108523462G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PDE2APhosphodiesterase. (944 aa)
ARRB2Arrestin beta 2. (466 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2305 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (507 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
PDE10APhosphodiesterase. (789 aa)
PDE8BPhosphodiesterase. (885 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
GNB4G protein subunit beta 4. (340 aa)
ENSRBIP00000007423Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
LOC108534220Phosphodiesterase. (693 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG13G protein subunit gamma 13. (67 aa)
PDE1CPhosphodiesterase. (768 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (672 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
SLC32A1Solute carrier family 32 member 1. (525 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
GNB3G protein subunit beta 3. (340 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (479 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
GRK4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (571 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (102 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (632 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (375 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PDE4APhosphodiesterase. (928 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (690 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (554 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
PDE1APhosphodiesterase. (501 aa)
GNAI2G protein subunit alpha i2. (355 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (414 aa)
PDE7APhosphodiesterase. (482 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
GNB1G protein subunit beta 1. (340 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1046 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (687 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GNB5G protein subunit beta 5. (403 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
ARRB1Arrestin beta 1. (418 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (308 aa)
GNASGNAS complex locus. (1041 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (883 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (427 aa)
PDE4BPhosphodiesterase. (736 aa)
PDE11APhosphodiesterase. (933 aa)
PDE8APhosphodiesterase. (827 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
PDE4DPhosphodiesterase. (809 aa)
LOC108541626Uncharacterized protein. (246 aa)
PDE7BPhosphodiesterase. (505 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (22%) [HD]