STRINGSTRING
LOC108524923 LOC108524923 LOC108535521 LOC108535521 TLR2 TLR2 MAPK3 MAPK3 LY96 LY96 SOCS1 SOCS1 HSPA1L HSPA1L JAK1 JAK1 TGFB2 TGFB2 MAPK10 MAPK10 LOC108533297 LOC108533297 CCR5 CCR5 LOC108523439 LOC108523439 BIRC3 BIRC3 MAP3K7 MAP3K7 TAB1 TAB1 IL12B IL12B TLR4 TLR4 TGFB1 TGFB1 MAPK9 MAPK9 LAMA2 LAMA2 MYD88 MYD88 BCL2 BCL2 TNF TNF BIRC2 BIRC2 PPIF PPIF NFKB1 NFKB1 TAB2 TAB2 LAMC3 LAMC3 LAMA4 LAMA4 CASP9 CASP9 PIK3R6 PIK3R6 IKBKG IKBKG LOC108512973 LOC108512973 HLA-DQA1 HLA-DQA1 HLA-DQB1 HLA-DQB1 ALOX5 ALOX5 LAMA1 LAMA1 HLA-DRA HLA-DRA IFNGR2 IFNGR2 MAP2K3 MAP2K3 IL10RA IL10RA RELA RELA HLA-DPA1 HLA-DPA1 LDLR LDLR NFKBIB NFKBIB ENSRBIP00000019541 ENSRBIP00000019541 LOC108519884 LOC108519884 IL10RB IL10RB MAP2K6 MAP2K6 ITGB1 ITGB1 LAMC2 LAMC2 LAMB2 LAMB2 IFNGR1 IFNGR1 CD40LG CD40LG LAMA3 LAMA3 TYK2 TYK2 CHUK CHUK MAPK1 MAPK1 TGFB3 TGFB3 CIITA CIITA IKBKB IKBKB MAPK14 MAPK14 LAMB3 LAMB3 LOC108519885 LOC108519885 GNAI2 GNAI2 LAMC1 LAMC1 HLA-DOB HLA-DOB IFNG IFNG IL12A IL12A MAPK13 MAPK13 HLA-DPB1 HLA-DPB1 AKT2 AKT2 AKT3 AKT3 MAPK11 MAPK11 ITGA6 ITGA6 HLA-DOA HLA-DOA CD40 CD40 TRAF6 TRAF6 STAT1 STAT1 IRAK4 IRAK4 TNFRSF1A TNFRSF1A NFKBIA NFKBIA GNAI3 GNAI3 PIK3CG PIK3CG IL10 IL10 NOS2 NOS2 BAD BAD CASP8 CASP8 HSPA2 HSPA2 LAMB4 LAMB4 PIK3R5 PIK3R5 BIRC7 BIRC7
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC108524923Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC108535521Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TLR2Toll-like receptor. (784 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
LY96Lymphocyte antigen 96. (160 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MAPK10Mitogen-activated protein kinase. (528 aa)
LOC108533297Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
CCR5C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (352 aa)
LOC108523439Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (512 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
MAPK9Mitogen-activated protein kinase. (407 aa)
LAMA2Laminin subunit alpha 2. (3094 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (206 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
LAMC3Laminin subunit gamma 3. (1535 aa)
LAMA4Laminin subunit alpha 4. (1816 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (372 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (754 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa)
LOC108512973Ig-like domain-containing protein. (263 aa)
HLA-DQA1Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (254 aa)
HLA-DQB1Ig-like domain-containing protein. (261 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
LAMA1Laminin subunit alpha 1. (3080 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
IFNGR2Interferon gamma receptor 2. (347 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa)
IL10RAInterleukin 10 receptor subunit alpha. (578 aa)
RELAUncharacterized protein. (282 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
LDLRLow density lipoprotein receptor. (819 aa)
NFKBIBNFKB inhibitor beta. (338 aa)
ENSRBIP00000019541Ig-like domain-containing protein. (264 aa)
LOC108519884Ig-like domain-containing protein. (266 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (937 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
IFNGR1Interferon gamma receptor 1. (489 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)
LAMA3Laminin subunit alpha 3. (3324 aa)
TYK2Tyrosine-protein kinase. (1187 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CIITAClass II major histocompatibility complex transactivator. (1125 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
LOC108519885Ig-like domain-containing protein. (266 aa)
GNAI2G protein subunit alpha i2. (355 aa)
LAMC1Laminin subunit gamma 1. (1587 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (273 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (159 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
AKT3AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
CD40CD40 molecule. (278 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
STAT1Signal transducer and activator of transcription. (787 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (461 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1106 aa)
IL10Interleukin 10. (178 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1126 aa)
BADBCL2 associated agonist of cell death. (167 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (542 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (619 aa)
LAMB4Laminin subunit beta 4. (1711 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (879 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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