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| | TICAM2 | Toll like receptor adaptor molecule 2. (235 aa) |
| | LOC108524923 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC108535521 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TLR2 | Toll-like receptor. (784 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1374 aa) |
| | PRKCG | Protein kinase C. (726 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | SRC | Tyrosine-protein kinase. (627 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (528 aa) |
| | LOC108533297 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | LOC108523439 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | MMP9 | Matrix metallopeptidase 9. (703 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | YWHAQ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (253 aa) |
| | ATF6B | Activating transcription factor 6 beta. (708 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1228 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (512 aa) |
| | EGR3 | Early growth response 3. (387 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | ELK1 | ETS domain-containing protein. (428 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (407 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (903 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (909 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (194 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (925 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1056 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (1014 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (442 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | IRF3 | IRF tryptophan pentad repeat domain-containing protein. (426 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (372 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa) |
| | STAT4 | Signal transducer and activator of transcription. (748 aa) |
| | STAT5B | Signal transducer and activator of transcription. (768 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | DDX3Y | DEAD-box helicase 3 Y-linked; Belongs to the DEAD box helicase family. (543 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa) |
| | RELA | Uncharacterized protein. (282 aa) |
| | TIRAP | TIR domain containing adaptor protein. (233 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1140 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (539 aa) |
| | RB1 | RB transcriptional corepressor 1. (815 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (522 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (753 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | TYK2 | Tyrosine-protein kinase. (1187 aa) |
| | YWHAZ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (151 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (370 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (427 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (553 aa) |
| | IRF7 | Interferon regulatory factor 7. (503 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (470 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | BIRC5 | Baculoviral IAP repeat containing 5. (142 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (989 aa) |
| | JAK3 | Tyrosine-protein kinase. (1124 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (789 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | FAS | Fas cell surface death receptor. (331 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (408 aa) |
| | CREBBP | CREB binding protein. (2422 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (503 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | DDX58 | DExD/H-box helicase 58. (914 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | STAT2 | Signal transducer and activator of transcription. (844 aa) |
| | EP300 | E1A binding protein p300. (2296 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1293 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (403 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa) |
| | AKT3 | AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (197 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1268 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (414 aa) |
| | STAT1 | Signal transducer and activator of transcription. (787 aa) |
| | DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (625 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (461 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | E2F3 | E2F transcription factor 3. (465 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (483 aa) |
| | SLC10A1 | Solute carrier family 10 member 1. (349 aa) |
| | IL6 | Interleukin 6. (214 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | TRAF3 | TNF receptor-associated factor. (477 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (542 aa) |
