STRINGSTRING
ATP6V0E1 ATP6V0E1 MAML2 MAML2 HEYL HEYL MAPK3 MAPK3 FN1 FN1 CDKN1B CDKN1B ATP6V1E2 ATP6V1E2 TCF7L2 TCF7L2 WNT6 WNT6 PIK3R1 PIK3R1 OASL OASL COL2A1 COL2A1 WNT3 WNT3 PIK3R3 PIK3R3 JAK1 JAK1 FASLG FASLG RBL2 RBL2 COL1A2 COL1A2 CREB3L2 CREB3L2 LOC108543093 LOC108543093 FZD9 FZD9 CRB3 CRB3 IKBKE IKBKE IFNB1 IFNB1 TBP TBP MTOR MTOR HEY1 HEY1 FZD5 FZD5 DLG1 DLG1 COL6A6 COL6A6 PARD3 PARD3 DLG2 DLG2 FZD10 FZD10 HES7 HES7 RHEB RHEB FOXO1 FOXO1 PPP2R5D PPP2R5D WNT2B WNT2B ATP6V1H ATP6V1H SLC9A3R1 SLC9A3R1 LFNG LFNG LLGL2 LLGL2 LAMA2 LAMA2 TLR3 TLR3 PSMC1 PSMC1 PPP2R1B PPP2R1B IRF1 IRF1 PTGER4 PTGER4 ITGB3 ITGB3 RFNG RFNG PPP2R2A PPP2R2A THBS3 THBS3 DVL3 DVL3 PPP2R1A PPP2R1A RAF1 RAF1 TCF7 TCF7 TNF TNF NOTCH4 NOTCH4 CSNK1A1L CSNK1A1L TCF7L1 TCF7L1 CREB3L1 CREB3L1 EIF4EBP1 EIF4EBP1 NFKB1 NFKB1 JAG1 JAG1 HES2 HES2 LAMC3 LAMC3 IRF3 IRF3 LAMA4 LAMA4 COL4A4 COL4A4 FZD7 FZD7 COL9A2 COL9A2 PPP2R5B PPP2R5B LLGL1 LLGL1 ATP6V1G2 ATP6V1G2 TBPL1 TBPL1 THBS2 THBS2 THBS4 THBS4 ITGA3 ITGA3 COL4A1 COL4A1 MAP2K1 MAP2K1 MPP5 MPP5 TADA3 TADA3 PDGFRB PDGFRB IKBKG IKBKG WNT10B WNT10B HES3 HES3 PXN PXN MAML3 MAML3 ATP6V1C2 ATP6V1C2 ITGA11 ITGA11 LOC108527145 LOC108527145 LAMA1 LAMA1 DVL2 DVL2 EGF EGF GRB2 GRB2 TERT TERT ITGAV ITGAV PIK3CA PIK3CA APC APC RELA RELA PPP2R2C PPP2R2C ITGA5 ITGA5 PARD6B PARD6B TRADD TRADD CDK4 CDK4 RB1 RB1 ATP6V1C1 ATP6V1C1 ATM ATM EIF2AK2 EIF2AK2 ITGB7 ITGB7 COL9A3 COL9A3 ITGB1 ITGB1 LAMC2 LAMC2 ATP6V1B1 ATP6V1B1 HDAC1 HDAC1 TNR TNR HRAS HRAS HEY2 HEY2 PPP2R5E PPP2R5E IBSP IBSP ITGA10 ITGA10 LAMB2 LAMB2 CTNNB1 CTNNB1 RBL1 RBL1 WNT8B WNT8B LAMA3 LAMA3 PTGS2 PTGS2 TYK2 TYK2 ATP6V1A ATP6V1A ITGA2B ITGA2B LOC108539219 LOC108539219 HLA-F HLA-F ITGA9 ITGA9 TSC1 TSC1 ATP6V0A4 ATP6V0A4 CREB3 CREB3 CHUK CHUK HDAC2 HDAC2 MAGI1 MAGI1 CCNA1 CCNA1 ITGA1 ITGA1 GSK3B GSK3B WNT16 WNT16 MFNG MFNG WNT9A WNT9A WNT5B WNT5B HLA-E HLA-E ATP6V0C ATP6V0C IFNAR1 IFNAR1 TCIRG1 TCIRG1 ATP6AP1 ATP6AP1 COL6A3 COL6A3 SPP1 SPP1 ITGA8 ITGA8 CCND1 CCND1 HES5 HES5 FADD FADD WNT8A WNT8A MAPK1 MAPK1 KRAS KRAS WNT9B WNT9B PPP2R2D PPP2R2D ATR ATR FZD4 FZD4 IKBKB IKBKB COL4A2 COL4A2 VWF VWF MX2 MX2 CCND3 CCND3 TP53 TP53 AXIN2 AXIN2 FAS FAS PARD6G PARD6G TUBG2 TUBG2 COL6A2 COL6A2 LAMB3 LAMB3 COL4A3 COL4A3 LOC108522717 LOC108522717 PPP2R3A PPP2R3A ISG15 ISG15 LAMC1 LAMC1 ITGB5 ITGB5 CREBBP CREBBP CREB5 CREB5 COL1A1 COL1A1 COL9A1 COL9A1 TNXB TNXB WNT3A WNT3A TSC2 TSC2 FZD3 FZD3 RBPJ RBPJ WNT1 WNT1 STAT2 STAT2 UBE3A UBE3A EP300 EP300 SOS1 SOS1 WNT7B WNT7B ITGA4 ITGA4 CREB1 CREB1 AKT2 AKT2 CCNE2 CCNE2 AKT3 AKT3 ITGB8 ITGB8 ATP6V0A2 ATP6V0A2 ITGB4 ITGB4 AXIN1 AXIN1 ATP6V0D2 ATP6V0D2 PRKACB PRKACB PTEN PTEN ITGA6 ITGA6 ITGB6 ITGB6 ITGA2 ITGA2 PIK3CD PIK3CD BAX BAX CHD4 CHD4 NOTCH2 NOTCH2 SOS2 SOS2 CCNA2 CCNA2 GNAS GNAS TNN TNN PPP2R2B PPP2R2B STAT1 STAT1 VTN VTN HES6 HES6 BAK1 BAK1 EGFR EGFR CDC42 CDC42 RBPJL RBPJL WNT11 WNT11 LOC108528436 LOC108528436 PRKCI PRKCI TNFRSF1A TNFRSF1A ATP6V1B2 ATP6V1B2 NRAS NRAS CCND2 CCND2 UBR4 UBR4 PPP2R5C PPP2R5C BCAP31 BCAP31 TBPL2 TBPL2 WNT7A WNT7A ATP6V1G1 ATP6V1G1 COL6A5 COL6A5 CREB3L3 CREB3L3 PATJ PATJ WNT5A WNT5A THBS1 THBS1 PARD6A PARD6A PKM PKM LOC108541626 LOC108541626 WNT2 WNT2 BAD BAD ITGA7 ITGA7 CHAD CHAD RELN RELN MX1 MX1 CDK6 CDK6 TRAF3 TRAF3 SCRIB SCRIB FZD6 FZD6 IFNAR2 IFNAR2 CASP8 CASP8 PPP2CA PPP2CA LAMB4 LAMB4 COL6A1 COL6A1 WNT10A WNT10A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
MAML2Mastermind like transcriptional coactivator 2. (1147 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
FN1Fibronectin 1. (2477 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ATP6V1E2ATPase H+ transporting V1 subunit E2. (226 aa)
TCF7L2HMG box domain-containing protein. (376 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
OASL2'-5'-oligoadenylate synthetase like. (449 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
RBL2RB transcriptional corepressor like 2. (1127 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
LOC108543093Ig-like domain-containing protein; Belongs to the MHC class I family. (378 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
CRB3Crumbs cell polarity complex component 3. (123 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
IFNB1Interferon beta 1. (187 aa)
TBPTATA-box binding protein. (338 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2527 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (861 aa)
COL6A6Collagen type VI alpha 6 chain. (2245 aa)
PARD3Par-3 family cell polarity regulator. (1356 aa)
DLG2Uncharacterized protein. (552 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
HES7Hes family bHLH transcription factor 7. (203 aa)
RHEBRas homolog, mTORC1 binding. (183 aa)
FOXO1Forkhead box O1. (539 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (349 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1020 aa)
LAMA2Laminin subunit alpha 2. (3094 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (903 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
IRF1Interferon regulatory factor. (325 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
RFNGRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (317 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
THBS3Thrombospondin 3. (956 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
RAF1Uncharacterized protein. (668 aa)
TCF7Transcription factor 7. (399 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
NOTCH4Notch receptor 4. (2000 aa)
CSNK1A1LCasein kinase 1 alpha 1 like. (243 aa)
TCF7L1Transcription factor 7 like 1. (440 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (442 aa)
EIF4EBP1Uncharacterized protein. (118 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
HES2Uncharacterized protein. (173 aa)
LAMC3Laminin subunit gamma 3. (1535 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (426 aa)
LAMA4Laminin subunit alpha 4. (1816 aa)
COL4A4Collagen type IV alpha 4 chain. (1690 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
COL9A2Collagen type IX alpha 2 chain. (780 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (595 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1042 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
THBS2Thrombospondin 2. (1081 aa)
THBS4Thrombospondin 4. (961 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1087 aa)
COL4A1Collagen type IV alpha 1 chain. (1668 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (665 aa)
TADA3Transcriptional adaptor 3. (432 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
HES3Hes family bHLH transcription factor 3. (220 aa)
PXNPaxillin. (1083 aa)
MAML3Mastermind like transcriptional coactivator 3. (1129 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (427 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1233 aa)
LOC108527145Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
LAMA1Laminin subunit alpha 1. (3080 aa)
DVL2Dishevelled segment polarity protein 2. (735 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1167 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
APCAPC regulator of WNT signaling pathway. (2768 aa)
RELAUncharacterized protein. (282 aa)
PPP2R2CProtein phosphatase 2 regulatory subunit Bgamma. (282 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1051 aa)
PARD6BPar-6 family cell polarity regulator beta. (372 aa)
TRADDTNFRSF1A associated via death domain. (248 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
RB1RB transcriptional corepressor 1. (815 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3026 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (538 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
COL9A3Uncharacterized protein. (684 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (937 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
TNRTenascin R. (1358 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
IBSPIntegrin binding sialoprotein. (317 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1168 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
CTNNB1Catenin beta 1. (781 aa)
RBL1RB transcriptional corepressor like 1. (1069 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
LAMA3Laminin subunit alpha 3. (3324 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
TYK2Tyrosine-protein kinase. (1187 aa)
ATP6V1AUncharacterized protein. (617 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1105 aa)
LOC108539219Protein kinase domain-containing protein. (224 aa)
HLA-FMajor histocompatibility complex, class I, F; Belongs to the MHC class I family. (369 aa)
ITGA9Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (548 aa)
TSC1TSC complex subunit 1. (1164 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (836 aa)
CREB3cAMP responsive element binding protein 3. (370 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
MAGI1Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1160 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (467 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (359 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (553 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (470 aa)
COL6A3Collagen type VI alpha 3 chain. (3172 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
CCND1Cyclin D1. (156 aa)
HES5Hes family bHLH transcription factor 5. (152 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2578 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
COL4A2Collagen type IV alpha 2 chain. (1712 aa)
VWFVon Willebrand factor. (2813 aa)
MX2MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (715 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (286 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
AXIN2Axin 2. (843 aa)
FASFas cell surface death receptor. (331 aa)
PARD6GPar-6 family cell polarity regulator gamma. (376 aa)
TUBG2Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (460 aa)
COL6A2Collagen type VI alpha 2 chain. (919 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
COL4A3Collagen type IV alpha 3 chain. (1644 aa)
LOC108522717Uncharacterized protein. (1434 aa)
PPP2R3AProtein phosphatase 2 regulatory subunit B''alpha. (1098 aa)
ISG15ISG15 ubiquitin like modifier. (167 aa)
LAMC1Laminin subunit gamma 1. (1587 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
CREBBPCREB binding protein. (2422 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (503 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
COL9A1Collagen type IX alpha 1 chain. (920 aa)
TNXBTenascin XB. (672 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
TSC2TSC complex subunit 2. (1805 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (531 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
STAT2Signal transducer and activator of transcription. (844 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
EP300E1A binding protein p300. (2296 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1293 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (403 aa)
AKT3AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (745 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
ITGB4Integrin beta. (1823 aa)
AXIN1Axin 1. (867 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
PTENUncharacterized protein. (555 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (771 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
BAXBCL2 associated X, apoptosis regulator. (197 aa)
CHD4Uncharacterized protein. (1906 aa)
NOTCH2Notch receptor 2. (2532 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1268 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
GNASGNAS complex locus. (1041 aa)
TNNTenascin N. (1299 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
STAT1Signal transducer and activator of transcription. (787 aa)
VTNSMB domain-containing protein. (478 aa)
HES6Hes family bHLH transcription factor 6. (212 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
CDC42Uncharacterized protein. (191 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (522 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
LOC108528436Ig-like domain-containing protein; Belongs to the MHC class I family. (394 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (581 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (540 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CCND2Uncharacterized protein; Belongs to the cyclin family. (244 aa)
UBR4Ubiquitin protein ligase E3 component n-recognin 4. (5187 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (571 aa)
BCAP31B cell receptor associated protein 31. (306 aa)
TBPL2TATA-box binding protein like 2. (375 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (344 aa)
ATP6V1G1V-type H+-transporting ATPase subunit G. (118 aa)
COL6A5Collagen type VI alpha 5 chain. (2566 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (483 aa)
PATJPATJ crumbs cell polarity complex component. (1883 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
THBS1Thrombospondin 1. (1170 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
LOC108541626Uncharacterized protein. (246 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
BADBCL2 associated agonist of cell death. (167 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
CHADChondroadherin. (359 aa)
RELNReelin. (3471 aa)
MX1MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (646 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
TRAF3TNF receptor-associated factor. (477 aa)
SCRIBScribble planar cell polarity protein. (1660 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (647 aa)
IFNAR2Uncharacterized protein. (516 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (542 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
LAMB4Laminin subunit beta 4. (1711 aa)
COL6A1Collagen type VI alpha 1 chain. (1027 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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